Research output per year
Research output per year
- 1 - 50 out of 52 results
Search results
-
2022
Dual-target inhibitors of bromodomain and extra-terminal proteins in cancer: A review from medicinal chemistry perspectives
Feng, L., Wang, G., Chen, Y., He, G., Liu, B., Liu, J., Chiang, C. M. & Ouyang, L., Mar 2022, In: Medicinal Research Reviews. 42, 2, p. 710-743 34 p.Research output: Contribution to journal › Review article › peer-review
24 Scopus citations -
2021
Polyvalent design in the cGAS-STING pathway
Bennett, Z. T., Li, S., Sumer, B. D. & Gao, J., Aug 2021, In: Seminars in Immunology. 56, 101580.Research output: Contribution to journal › Review article › peer-review
Open Access8 Scopus citations -
Targeting Bromodomain and Extraterminal Proteins for Drug Discovery: From Current Progress to Technological Development
Tang, P., Zhang, J., Liu, J., Chiang, C. M. & Ouyang, L., Mar 11 2021, In: Journal of Medicinal Chemistry. 64, 5, p. 2419-2435 17 p.Research output: Contribution to journal › Review article › peer-review
Open Access72 Scopus citations -
2020
Exploiting nanoscale cooperativity for precision medicine
Wilhelm, J., Wang, Z., Sumer, B. D. & Gao, J., Jan 2020, In: Advanced Drug Delivery Reviews. 158, p. 63-72 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access18 Scopus citations -
2019
Targeting NAD + Metabolism to Enhance Radiation Therapy Responses
Lewis, J. E., Singh, N., Holmila, R. J., Sumer, B. D., Williams, N. S., Furdui, C. M., Kemp, M. L. & Boothman, D. A., Jan 2019, In: Seminars in Radiation Oncology. 29, 1, p. 6-15 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access18 Scopus citations -
2018
Antibody targeting of phosphatidylserine for the detection and immunotherapy of cancer
Belzile, O., Huang, X., Gong, J., Carlson, J., Schroit, A. J., Brekken, R. A. & Freimark, B. D., 2018, In: ImmunoTargets and Therapy. 7, p. 1-14 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access23 Scopus citations -
Cooperativity Principles in Self-Assembled Nanomedicine
Li, Y., Wang, Y., Huang, G. & Gao, J., Jun 13 2018, In: Chemical Reviews. 118, 11, p. 5359-5391 33 p.Research output: Contribution to journal › Review article › peer-review
121 Scopus citations -
Design of synthetic materials for intracellular delivery of RNAs: From siRNA-mediated gene silencing to CRISPR/Cas gene editing
Miller, J. B. & Siegwart, D. J., Oct 1 2018, In: Nano Research. 11, 10, p. 5310-5337 28 p.Research output: Contribution to journal › Review article › peer-review
29 Scopus citations -
Emerging Contributions of Cancer/Testis Antigens to Neoplastic Behaviors
Gibbs, Z. A. & Whitehurst, A. W., Oct 2018, In: Trends in Cancer. 4, 10, p. 701-712 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access74 Scopus citations -
Modulators of redox metabolism in head and neck cancer
Chen, X., Mims, J., Huang, X., Singh, N., Motea, E., Planchon, S. M., Beg, M. S., Tsang, A. W., Porosnicu, M., Kemp, M. L., Boothman, D. A. & Furdui, C. M., Dec 1 2018, In: Antioxidants and Redox Signaling. 29, 16, p. 1660-1690 31 p.Research output: Contribution to journal › Review article › peer-review
Open Access13 Scopus citations -
Optical molecular imaging for tumor detection and image-guided surgery
Wang, C., Wang, Z., Zhao, T., Li, Y., Huang, G., Sumer, B. D. & Gao, J., Mar 2018, In: Biomaterials. 157, p. 62-75 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access167 Scopus citations -
Translational research to enable personalized treatment of cystic fibrosis
Hagemeijer, M. C., Siegwart, D. J., Strug, L. J., Cebotaru, L., Torres, M. J., Sofoluwe, A. & Beekman, J. M., Mar 2018, In: Journal of Cystic Fibrosis. 17, 2, p. S46-S51Research output: Contribution to journal › Review article › peer-review
Open Access17 Scopus citations -
2017
Investigation of endosome and lysosome biology by ultra pH-sensitive nanoprobes
Wang, C., Zhao, T., Li, Y., Huang, G., White, M. A. & Gao, J., Apr 2017, In: Advanced Drug Delivery Reviews. 113, p. 87-96 10 p.Research output: Contribution to journal › Review article › peer-review
124 Scopus citations -
Involvement of Brd4 in different steps of the papillomavirus life cycle
Iftner, T., Haedicke-Jarboui, J., Wu, S. Y. & Chiang, C. M., Mar 2 2017, In: Virus Research. 231, p. 76-82 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access42 Scopus citations -
2016
Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer
Birge, R. B., Boeltz, S., Kumar, S., Carlson, J., Wanderley, J., Calianese, D., Barcinski, M., Brekken, R. A., Huang, X., Hutchins, J. T., Freimark, B., Empig, C., Mercer, J., Schroit, A. J., Schett, G. & Herrmann, M., Jun 1 2016, In: Cell Death and Differentiation. 23, 6, p. 962-978 17 p.Research output: Contribution to journal › Review article › peer-review
Open Access455 Scopus citations -
Phospho-BRD4: transcription plasticity and drug targeting
Chiang, C. M., Mar 1 2016, In: Drug Discovery Today: Technologies. 19, p. 17-22 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access40 Scopus citations -
2015
Nanotechnology-enabled delivery of NQO1 bioactivatable drugs
Ma, X., Moore, Z. R., Huang, G., Huang, X., Boothman, D. A. & Gao, J., Sep 14 2015, In: Journal of Drug Targeting. 23, 7-8, p. 672-680 9 p.Research output: Contribution to journal › Review article › peer-review
26 Scopus citations -
2014
Cause and consequence of cancer/testis antigen activation in cancer
Whitehurst, A. W., Jan 2014, In: Annual review of pharmacology and toxicology. 54, p. 251-272 22 p.Research output: Contribution to journal › Review article › peer-review
193 Scopus citations -
Tumor-selective, futile redox cycle-induced bystander effects elicited by NQO1 bioactivatable radiosensitizing drugs in triple-negative breast cancers
Cao, L., Li, L. S., Spruell, C., Xiao, L., Chakrabarti, G., Bey, E. A., Reinicke, K. E., Srougi, M. C., Moore, Z., Dong, Y., Vo, P., Kabbani, W., Yang, C. R., Wang, X., Fattah, F., Morales, J. C., Motea, E. A., Bornmann, W. G., Yordy, J. S. & Boothman, D. A., Jul 10 2014, In: Antioxidants and Redox Signaling. 21, 2, p. 237-250 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access34 Scopus citations -
2012
ATRP in the design of functional materials for biomedical applications
Siegwart, D. J., Oh, J. K. & Matyjaszewski, K., Jan 2012, In: Progress in Polymer Science (Oxford). 37, 1, p. 18-37 20 p.Research output: Contribution to journal › Review article › peer-review
Open Access503 Scopus citations -
2011
Nanonization strategies for poorly water-soluble drugs
Chen, H., Khemtong, C., Yang, X., Chang, X. & Gao, J., Apr 2011, In: Drug Discovery Today. 16, 7-8, p. 354-360 7 p.Research output: Contribution to journal › Review article › peer-review
556 Scopus citations -
Shape-specific polymeric nanomedicine: Emerging opportunities and challenges
Tao, L., Hu, W., Liu, Y., Huang, G., Sumer, B. D. & Gao, J., Jan 2011, In: Experimental Biology and Medicine. 236, 1, p. 20-29 10 p.Research output: Contribution to journal › Review article › peer-review
132 Scopus citations -
2009
DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets
Li, L. S., Morales, J. C., Veigl, M., Sedwick, D., Greer, S., Meyers, M., Wagner, M., Fishel, R. & Boothman, D. A., Oct 2009, In: British Journal of Pharmacology. 158, 3, p. 679-692 14 p.Research output: Contribution to journal › Review article › peer-review
65 Scopus citations -
p53 sumoylation: Mechanistic insights from reconstitution studies
Wu, S. Y. & Chiang, C. M., Oct 1 2009, In: Epigenetics. 4, 7, p. 445-451 7 p.Research output: Contribution to journal › Review article › peer-review
27 Scopus citations -
Polymeric nanomedicine for cancer MR imaging and drug delivery
Khemtong, C., Kessinger, C. W. & Gao, J., 2009, In: Chemical Communications. 24, p. 3497-3510 14 p.Research output: Contribution to journal › Review article › peer-review
166 Scopus citations -
2008
Polymer implants for intratumoral drug delivery and cancer therapy
Weinberg, B. D., Blanco, E. & Gao, J., May 2008, In: Journal of Pharmaceutical Sciences. 97, 5, p. 1681-1702 22 p.Research output: Contribution to journal › Review article › peer-review
131 Scopus citations -
Stress-induced premature senescence (SIPS) - Influence of sips on radiotherapy
Suzuki, M. & Boothman, D. A., 2008, In: Journal of radiation research. 49, 2, p. 105-112 8 p.Research output: Contribution to journal › Review article › peer-review
106 Scopus citations -
The development of microgels/nanogels for drug delivery applications
Oh, J. K., Drumright, R., Siegwart, D. J. & Matyjaszewski, K., Apr 2008, In: Progress in Polymer Science (Oxford). 33, 4, p. 448-477 30 p.Research output: Contribution to journal › Review article › peer-review
1412 Scopus citations -
2007
Functionalized micellar systems for cancer targeted drug delivery
Sutton, D., Nasongkla, N., Blanco, E. & Gao, J., Jun 2007, In: Pharmaceutical Research. 24, 6, p. 1029-1046 18 p.Research output: Contribution to journal › Review article › peer-review
492 Scopus citations -
2006
Challenge and promise: Roles for clusterin in pathogenesis, progression and therapy of cancer
Shannan, B., Seifert, M., Leskov, K., Willis, J., Boothman, D., Tilgen, W. & Reichrath, J., Jan 2006, In: Cell Death and Differentiation. 13, 1, p. 12-19 8 p.Research output: Contribution to journal › Review article › peer-review
292 Scopus citations -
Clusterin and DNA repair: A new function in cancer for a key player in apoptosis and cell cycle control
Shannan, B., Seifert, M., Boothman, D. A., Tilgen, W. & Reichrath, J., Sep 2006, In: Journal of Molecular Histology. 37, 5-7, p. 183-188 6 p.Research output: Contribution to journal › Review article › peer-review
67 Scopus citations -
Harnessing RNAi for Analyses of Ras Signaling and Transformation
Whitehurst, A. W. & White, M. A., Jan 1 2006, In: Methods in Enzymology. 407, p. 259-268 10 p.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
New tricks for old drugs: The anticarcinogenic potential of DNA repair inhibitors
Bentle, M. S., Bey, E. A., Dong, Y., Reinicke, K. E. & Boothman, D. A., Sep 2006, In: Journal of Molecular Histology. 37, 5-7, p. 203-218 16 p.Research output: Contribution to journal › Review article › peer-review
63 Scopus citations -
The general transcription machinery and general cofactors.
Thomas, M. C. & Chiang, C. M., 2006, In: Critical reviews in biochemistry and molecular biology. 41, 3, p. 105-178 74 p.Research output: Contribution to journal › Review article › peer-review
644 Scopus citations -
2004
IR-inducible clusterin gene expression: A protein with potential roles in ionizing radiation-induced adaptive responses, genomic instability, and bystander effects
Klokov, D., Criswell, T., Leskov, K. S., Araki, S., Mayo, L. & Boothman, D. A., Dec 2 2004, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 568, 1 SPEC. ISS., p. 97-110 14 p.Research output: Contribution to journal › Review article › peer-review
73 Scopus citations -
Role of DNA mismatch repair in apoptotic responses to therapeutic agents
Meyers, M., Hwang, A., Wagner, M. W. & Boothman, D. A., 2004, In: Environmental and Molecular Mutagenesis. 44, 4, p. 249-264 16 p.Research output: Contribution to journal › Review article › peer-review
54 Scopus citations -
Thiol Oxidation Enforces Phosphatidylserine Externalization in Apoptosis-Sensitive and -Resistant Cells Through a Δψm/Cytochrome c Release-Dependent Mechanism
Forsberg, A. J., Kagan, V. E. & Schroit, A. J., Apr 2004, In: Antioxidants and Redox Signaling. 6, 2, p. 203-208 6 p.Research output: Contribution to journal › Review article › peer-review
10 Scopus citations -
Vitamin E Inhibits Anti-Fas-Induced Phosphatidylserine Oxidation but Does Not Affect Its Externalization during Apoptosis in Jurkat T Cells and Their Phagocytosis by J774A.1 Macrophages
Serinkan, B. F., Tyurina, Y. Y., Babu, H., Djukic, M., Quinn, P. J., Schroit, A. & Kagan, V. E., Apr 2004, In: Antioxidants and Redox Signaling. 6, 2, p. 227-236 10 p.Research output: Contribution to journal › Review article › peer-review
11 Scopus citations -
2003
Aminophospholipid Asymmetry: A Matter of Life and Death
Balasubramanian, K. & Schroit, A. J., 2003, In: Annual review of physiology. 65, p. 701-734 34 p.Research output: Contribution to journal › Review article › peer-review
333 Scopus citations -
Mesenchymal stem cells and tissue engineering for orthopaedic surgery.
Gao, J. & Caplan, A. I., 2003, In: La Chirurgia degli organi di movimento. 88, 3, p. 305-316 12 p.Research output: Contribution to journal › Review article › peer-review
57 Scopus citations -
Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation
Criswell, T., Leskov, K., Miyamoto, S., Luo, G. & Boothman, D. A., Sep 1 2003, In: Oncogene. 22, 37 REV. ISS. 3, p. 5813-5827 15 p.Research output: Contribution to journal › Review article › peer-review
221 Scopus citations -
2002
Sp1 and AP2 regulate but do not constitute TATA-less human TAFII55 core promoter activity
Zhou, T. & Chiang, C. M., Oct 1 2002, In: Nucleic acids research. 30, 19, p. 4145-4157 13 p.Research output: Contribution to journal › Review article › peer-review
Open Access25 Scopus citations -
2001
Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
Pearson, G., Robinson, F., Gibson, T. B., Xu, B. E., Karandikar, M., Berman, K. & Cobb, M. H., 2001, In: Endocrine reviews. 22, 2, p. 153-183 31 p.Research output: Contribution to journal › Review article › peer-review
3667 Scopus citations -
1999
Cell membrane lipids as experimental therapeutic targets
Killion, J. J. & Schroit, A. J., Sep 1 1999, In: Expert Opinion on Therapeutic Targets. 3, 3, p. 453-468 16 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
1997
Pathophysiologic implications of membrane phospholipid asymmetry in blood cells
Zwaal, R. F. A. & Schroit, A. J., Feb 15 1997, In: Blood. 89, 4, p. 1121-1132 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access1238 Scopus citations -
1996
Membrane phospholipid asymmetry: Host response to the externalization of phosphatidylserine
Bruckheimer, E. M. & Schroit, A. J., Jun 1996, In: Journal of Leukocyte Biology. 59, 6, p. 784-788 5 p.Research output: Contribution to journal › Review article › peer-review
27 Scopus citations -
Role of translocases in the generation of phosphatidylserine asymmetry
Diaz, C. & Schroit, A. J., 1996, In: Journal of Membrane Biology. 151, 1, p. 1-9 9 p.Research output: Contribution to journal › Review article › peer-review
121 Scopus citations -
1994
Immediate X-ray-inducible responses from mammalian cells
Boothman, D. A., Majmudar, G. & Johnson, T., 1994, In: Radiation research. 138, 1 SUPPL., p. S44-S46Research output: Contribution to journal › Review article › peer-review
29 Scopus citations -
1991
Transbilayer movement of phospholipids in red cell and platelet membranes
Schroit, A. J. & Zwaal, R. F. A., Nov 13 1991, In: BBA - Reviews on Biomembranes. 1071, 3, p. 313-329 17 p.Research output: Contribution to journal › Review article › peer-review
298 Scopus citations -
1990
The role of X-ray-induced DNA repair processes in mutagenesis and carcinogenesis.
Boothman, D. A., Hughes, E. N. & Pardee, A. B., 1990, In: Progress in clinical and biological research. 340 E, p. 319-327 9 p.Research output: Contribution to journal › Review article › peer-review
4 Scopus citations