Int Med - Touchstone Diab Ctr – Research output — University of Texas Southwestern Medical Center

2023

Adipose tissue fibrosis: the unwanted houseguest invited by obesity

Gliniak, C. M., Pedersen, L. & Scherer, P. E., 2023, In: Journal of Endocrinology. 259, 3, e230180.

Research output: Contribution to journal › Review article › peer-review

Open Access

3 Scopus citations

Pathophysiology of cellulite: Possible involvement of selective endotoxemia

Kruglikov, I. L. & Scherer, P. E., Jan 2023, In: Obesity Reviews. 24, 1, e13517.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

Update on Adipose Tissue and Cancer

Brown, K. A. & Scherer, P. E., Dec 1 2023, In: Endocrine reviews. 44, 6, p. 961-974 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

9 Scopus citations

2022

Adiponectin and cardiometabolic trait and mortality: where do we go?

Jang, A. Y., Scherer, P. E., Kim, J. Y., Lim, S. & Koh, K. K., May 1 2022, In: Cardiovascular Research. 118, 9, p. 2074-2084 11 p.

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Crosstalk between adipose tissue and the heart: An update

Li, C., Sun, X. N., Zhao, S. & Scherer, P. E., Sep 1 2022, In: Journal of Translational Internal Medicine. 10, 3, p. 219-226 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

6 Scopus citations

Intercellular and interorgan crosstalk through adipocyte extracellular vesicles

Crewe, C. & Scherer, P. E., Feb 2022, In: Reviews in Endocrine and Metabolic Disorders. 23, 1, p. 61-69 9 p.

Research output: Contribution to journal › Review article › peer-review

29 Scopus citations

Mitochondrial regulation and white adipose tissue homeostasis

Zhu, Q., An, Y. A. & Scherer, P. E., Apr 2022, In: Trends in Cell Biology. 32, 4, p. 351-364 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

24 Scopus citations

Phenotypical Conversions of Dermal Adipocytes as Pathophysiological Steps in Inflammatory Cutaneous Disorders

Kruglikov, I. L., Zhang, Z. & Scherer, P. E., Apr 1 2022, In: International journal of molecular sciences. 23, 7, 3828.

Research output: Contribution to journal › Review article › peer-review

Open Access

5 Scopus citations

The metabolic syndrome, thiazolidinediones, and implications for intersection of chronic and inflammatory disease

Colca, J. R. & Scherer, P. E., Jan 2022, In: Molecular Metabolism. 55, 101409.

Research output: Contribution to journal › Review article › peer-review

Open Access

14 Scopus citations

Why does obesity cause diabetes?

Klein, S., Gastaldelli, A., Yki-Järvinen, H. & Scherer, P. E., Jan 4 2022, In: Cell Metabolism. 34, 1, p. 11-20 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

190 Scopus citations

2021

Adiponectin, Leptin and Cardiovascular Disorders

Zhao, S., Kusminski, C. M. & Scherer, P. E., Jan 8 2021, In: Circulation research. 128, 1, p. 136-149 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

154 Scopus citations

Alternate therapeutic pathways for PARP inhibitors and potential mechanisms of resistance

Kim, D. S., Camacho, C. V. & Kraus, W. L., Jan 2021, In: Experimental and Molecular Medicine. 53, 1, p. 42-51 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

90 Scopus citations

Metabolic Functions of G Protein-Coupled Receptors and β-Arrestin-Mediated Signaling Pathways in the Pathophysiology of Type 2 Diabetes and Obesity

Oliveira de Souza, C., Sun, X. & Oh, D., Aug 23 2021, In: Frontiers in Endocrinology. 12, 715877.

Research output: Contribution to journal › Review article › peer-review

Open Access

12 Scopus citations

Obesity, diabetes, and increased cancer progression

Kim, D. S. & Scherer, P. E., Nov 2021, In: Diabetes and Metabolism Journal. 45, 6, p. 799-812 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

75 Scopus citations

Preexisting and inducible endotoxemia as crucial contributors to the severity of COVID-19 outcomes

Kruglikov, I. L. & Scherer, P. E., Feb 18 2021, In: PLoS pathogens. 17, 2, e1009306.

Research output: Contribution to journal › Review article › peer-review

Open Access

26 Scopus citations

Supercritical fluid chromatography hyphenated to mass spectrometry for metabolomics applications

Gordillo, R., Jan 2021, In: Journal of Separation Science. 44, 1, p. 448-463 16 p.

Research output: Contribution to journal › Review article › peer-review

18 Scopus citations

2020

Caveolin as a universal target in dermatology

Kruglikov, I. L. & Scherer, P. E., Jan 1 2020, In: International journal of molecular sciences. 21, 1, 80.

Research output: Contribution to journal › Review article › peer-review

Open Access

11 Scopus citations

Obesity and diabetes as comorbidities for COVID-19: Underlying mechanisms and the role of viral–bacterial interactions

Kruglikov, I. L., Shah, M. & Scherer, P. E., Sep 2020, In: eLife. 9, p. 1-21 21 p., e61330.

Research output: Contribution to journal › Review article › peer-review

Open Access

67 Scopus citations

PARPs and ADP-ribosylation in RNA biology: From RNA expression and processing to protein translation and proteostasis

Kim, D. S., Challa, S., Jones, A. & Kraus, W. L., Mar 1 2020, In: Genes and Development. 34, 5, p. 302-320 19 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

78 Scopus citations

Revisiting PPARγ as a new friend of GPR120 in the treatment of metabolic disorders

Paschoal, V. A. & Oh, D. Y., Jan 1 2020, In: Adipocyte. 9, 1, p. 649-652 4 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

5 Scopus citations

The Role of Ceramides in Diabetes and Cardiovascular Disease Regulation of Ceramides by Adipokines

Field, B. C., Gordillo, R. & Scherer, P. E., Oct 2 2020, In: Frontiers in Endocrinology. 11, 569250.

Research output: Contribution to journal › Review article › peer-review

Open Access

42 Scopus citations

2019

Adipogenesis and metabolic health

Ghaben, A. L. & Scherer, P. E., Apr 1 2019, In: Nature Reviews Molecular Cell Biology. 20, 4, p. 242-258 17 p.

Research output: Contribution to journal › Review article › peer-review

798 Scopus citations

Beyond adiponectin and leptin: Adipose tissue-derived mediators of inter-organ communication

Funcke, J. B. & Scherer, P. E., 2019, In: Journal of lipid research. 60, 10, p. 1648-1697 50 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

179 Scopus citations

Caveolin-1 as a pathophysiological factor and target in psoriasis

Kruglikov, I. L. & Scherer, P. E., Dec 1 2019, In: npj Aging and Mechanisms of Disease. 5, 1, 4.

Research output: Contribution to journal › Review article › peer-review

Open Access

24 Scopus citations

Caveolin-1 in skin aging – From innocent bystander to major contributor

Kruglikov, I. L., Zhang, Z. & Scherer, P. E., Nov 2019, In: Ageing Research Reviews. 55, 100959.

Research output: Contribution to journal › Review article › peer-review

25 Scopus citations

Critical lipids link breastfeeding to healthy adipose tissue in infancy and adulthood

Gliniak, C. M. & Scherer, P. E., Jun 3 2019, In: Journal of Clinical Investigation. 129, 6, p. 2198-2200 3 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

3 Scopus citations

Hyaluronan in adipogenesis, adipose tissue physiology and systemic metabolism

Zhu, Y., Kruglikov, I. L., Akgul, Y. & Scherer, P. E., May 2019, In: Matrix Biology. 78-79, p. 284-291 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

38 Scopus citations

Imaging metabolically active fat: A literature review and mechanistic insights

Frankl, J., Sherwood, A., Clegg, D. J., Scherer, P. E. & Öz, O. K., Nov 2019, In: International journal of molecular sciences. 20, 21, 5509.

Research output: Contribution to journal › Review article › peer-review

Open Access

11 Scopus citations

Lowering ceramides to overcome diabetes

Kusminski, C. M. & Scherer, P. E., Jul 26 2019, In: Science. 365, 6451, p. 319-320 2 p.

Research output: Contribution to journal › Review article › peer-review

21 Scopus citations

Remodeling of Murine Mammary Adipose Tissue during Pregnancy, Lactation, and Involution

Wang, Q. A. & Scherer, P. E., Sep 1 2019, In: Journal of mammary gland biology and neoplasia. 24, 3, p. 207-212 6 p.

Research output: Contribution to journal › Review article › peer-review

21 Scopus citations

The many secret lives of adipocytes: implications for diabetes

Scherer, P. E., Feb 1 2019, In: Diabetologia. 62, 2, p. 223-232 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

107 Scopus citations

The Role of Immature and Mature Adipocytes in Hair Cycling

Kruglikov, I. L., Zhang, Z. & Scherer, P. E., Feb 2019, In: Trends in Endocrinology and Metabolism. 30, 2, p. 93-105 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

30 Scopus citations

Transcriptional brakes on the road to adipocyte thermogenesis

Shao, M. & Gupta, R. K., Jan 2019, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1864, 1, p. 20-28 9 p.

Research output: Contribution to journal › Review article › peer-review

18 Scopus citations

Unfolded protein response as a therapeutic target in cardiovascular disease

Zhang, G., Wang, X., Gillette, T. G., Deng, Y. & Wang, Z. V., 2019, In: Current topics in medicinal chemistry. 19, 21, p. 1902-1917 16 p.

Research output: Contribution to journal › Review article › peer-review

29 Scopus citations

2018

Immunologic and endocrine functions of adipose tissue: implications for kidney disease

Zhu, Q. & Scherer, P. E., Feb 1 2018, In: Nature Reviews Nephrology. 14, 2, p. 105-120 16 p.

Research output: Contribution to journal › Review article › peer-review

116 Scopus citations

2017

Adipose Tissue: A Safe Haven for Parasites?

Tanowitz, H. B., Scherer, P. E., Mota, M. M. & Figueiredo, L. M., Apr 1 2017, In: Trends in Parasitology. 33, 4, p. 276-284 9 p.

Research output: Contribution to journal › Review article › peer-review

67 Scopus citations

Alterations in pancreatic β cell function and Trypanosoma cruzi infection: evidence from human and animal studies

Dufurrena, Q., Amjad, F. M., Scherer, P. E., Weiss, L. M., Nagajyothi, J., Roth, J., Tanowitz, H. B. & Kuliawat, R., Mar 1 2017, In: Parasitology Research. 116, 3, p. 827-838 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

8 Scopus citations

Insulin and glucagon: Partners for life

Holst, J. J., Holland, W. L., Gromada, J., Lee, Y. H., Unger, R. H., Yan, H., Sloop, K. W., Kieffer, T. J., Damond, N. & Herrera, P. L., Apr 1 2017, In: Endocrinology. 158, 4, p. 696-701 6 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

74 Scopus citations

Na_v1.8 neurons are involved in limiting acute phase responses to dietary fat

Udit, S., Burton, M., Rutkowski, J. M., Lee, S., Bookout, A. L., Scherer, P. E., Elmquist, J. K. & Gautron, L., Oct 2017, In: Molecular Metabolism. 6, 10, p. 1081-1091 11 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

16 Scopus citations

Pas de Deux: Glucagon and Thyroid Hormone Moving in Perfect Synchrony

Ghaben, A. L. & Scherer, P. E., Mar 3 2017, In: Circulation research. 120, 5, p. 762-764 3 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

Sorting out adipocyte precursors and their role in physiology and disease

Hepler, C., Vishvanath, L. & Gupta, R. K., Jan 15 2017, In: Genes and Development. 31, 2, p. 127-140 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

98 Scopus citations

The ominous triad of adipose tissue dysfunction: Inflammation, fibrosis, and impaired angiogenesis

Crewe, C., An, Y. A. & Scherer, P. E., Jan 3 2017, In: Journal of Clinical Investigation. 127, 1, p. 74-82 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

470 Scopus citations

2016

Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk

Stern, J. H., Rutkowski, J. M. & Scherer, P. E., May 10 2016, In: Cell Metabolism. 23, 5, p. 770-784 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

699 Scopus citations

Adiponectin, the past two decades

Wang, Z. V. & Scherer, P. E., Apr 1 2016, In: Journal of molecular cell biology. 8, 2, p. 93-100 8 p.

Research output: Contribution to journal › Review article › peer-review

409 Scopus citations

Dermal Adipocytes: From Irrelevance to Metabolic Targets?

Kruglikov, I. L. & Scherer, P. E., Jan 1 2016, In: Trends in Endocrinology and Metabolism. 27, 1, p. 1-10 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

90 Scopus citations

Glucagon is the key factor in the development of diabetes

Lee, Y. H., Wang, M-Y., Yu, X. X. & Unger, R. H., Jul 1 2016, In: Diabetologia. 59, 7, p. 1372-1375 4 p.

Research output: Contribution to journal › Review article › peer-review

118 Scopus citations

Glucagon therapeutics: Dawn of a new era for diabetes care

Davidson, J. A., Holland, W. L., Roth, M. G., Wang, M-Y., Lee, Y. H., Yu, X., McCorkle, S. K., Scherer, P. E. & Unger, R. H., Oct 1 2016, In: Diabetes/Metabolism Research and Reviews. 32, 7, p. 660-665 6 p.

Research output: Contribution to journal › Review article › peer-review