Research output per year
Research output per year
- 38 results
Search results
-
2018
Comparison of telomere length measurement methods
Lai, T. P., Wright, W. E. & Shay, J. W., Mar 5 2018, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 373, 1741, 20160451.Research output: Contribution to journal › Review article › peer-review
Open Access170 Scopus citations -
2014
Alternative splicing regulation of telomerase: A new paradigm?
Wong, M. S., Wright, W. E. & Shay, J. W., Oct 1 2014, In: Trends in Genetics. 30, 10, p. 430-438 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access70 Scopus citations -
Telomeropathies: An emerging spectrum disorder
Holohan, B., Wright, W. E. & Shay, J. W., 2014, In: Journal of Cell Biology. 205, 3, p. 289-299 11 p.Research output: Contribution to journal › Review article › peer-review
132 Scopus citations -
2012
Is telomerase a viable target in cancer?
Buseman, C. M., Wright, W. E. & Shay, J. W., Feb 1 2012, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 730, 1-2, p. 90-97 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access119 Scopus citations -
2011
Role of telomeres and telomerase in cancer
Shay, J. W. & Wright, W. E., Dec 2011, In: Seminars in Cancer Biology. 21, 6, p. 349-353 5 p.Research output: Contribution to journal › Review article › peer-review
401 Scopus citations -
Targeting telomerase-expressing cancer cells
Ouellette, M. M., Wright, W. E. & Shay, J. W., Jul 2011, In: Journal of Cellular and Molecular Medicine. 15, 7, p. 1433-1442 10 p.Research output: Contribution to journal › Review article › peer-review
63 Scopus citations -
2010
Telomere biology in Metazoa
Gomes, N. M. V., Shay, J. W. & Wright, W. E., Sep 2010, In: FEBS Letters. 584, 17, p. 3741-3751 11 p.Research output: Contribution to journal › Review article › peer-review
Open Access143 Scopus citations -
Telomeres and telomerase in normal and cancer stem cells
Shay, J. W. & Wright, W. E., Sep 2010, In: FEBS Letters. 584, 17, p. 3819-3825 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access184 Scopus citations -
2009
Is telomerase a novel target for metastatic colon cancer?
Roig, A. I., Wright, W. E. & Shay, J. W., Oct 2009, In: Current Colorectal Cancer Reports. 5, 4, p. 203-208 6 p.Research output: Contribution to journal › Review article › peer-review
11 Scopus citations -
2007
Hallmarks of telomeres in ageing research
Shay, J. W. & Wright, W. E., Jan 2007, In: Journal of Pathology. 211, 2, p. 114-123 10 p.Research output: Contribution to journal › Review article › peer-review
165 Scopus citations -
Human diseases of telomerase dysfunction: Insights into tissue aging
Garcia, C. K., Wright, W. E. & Shay, J. W., Dec 2007, In: Nucleic acids research. 35, 22, p. 7406-7416 11 p.Research output: Contribution to journal › Review article › peer-review
129 Scopus citations -
2006
Telomerase therapeutics for cancer: Challenges and new directions
Shay, J. W. & Wright, W. E., Jul 2006, In: Nature Reviews Drug Discovery. 5, 7, p. 577-584 8 p.Research output: Contribution to journal › Review article › peer-review
387 Scopus citations -
2005
Fine-tuning the chromosome ends: The last base of human telomeres
Sfeir, A. J., Shay, J. W. & Wright, W. E., Nov 2005, In: Cell Cycle. 4, 11, p. 1467-1470 4 p.Research output: Contribution to journal › Review article › peer-review
Open Access12 Scopus citations -
Mechanism-based combination telomerase inhibition therapy
Shay, J. W. & Wright, W. E., Jan 2005, In: Cancer Cell. 7, 1, p. 1-2 2 p.Research output: Contribution to journal › Review article › peer-review
45 Scopus citations -
Senescence and immortalization: Role of telomeres and telomerase
Shay, J. W. & Wright, W. E., 2005, In: Carcinogenesis. 26, 5, p. 867-874 8 p.Research output: Contribution to journal › Review article › peer-review
576 Scopus citations -
Telomerase as a therapeutic target in cancer
Gellert, G. C., Jackson, S. R., Dikmen, Z. G., Wright, W. E. & Shay, J. W., 2005, In: Drug Discovery Today: Disease Mechanisms. 2, 2, p. 159-164 6 p.Research output: Contribution to journal › Review article › peer-review
27 Scopus citations -
The longevity gender gap: are telomeres the explanation?
Aviv, A., Shay, J., Christensen, K. & Wright, W., Jun 8 2005, In: Science of aging knowledge environment : SAGE KE. 2005, 23, p. pe16Research output: Contribution to journal › Review article › peer-review
58 Scopus citations -
2004
Telomeres are double-strand DNA breaks hidden from DNA damage responses
Shay, J. W. & Wright, W. E., May 21 2004, In: Molecular cell. 14, 4, p. 420-421 2 p.Research output: Contribution to journal › Review article › peer-review
22 Scopus citations -
2002
A model for heterogeneous nuclear ribonucleoproteins in telomere and telomerase regulation
Ford, L. P., Wright, W. E. & Shay, J. W., Jan 21 2002, In: Oncogene. 21, 4 REV. ISS. 1, p. 580-583 4 p.Research output: Contribution to journal › Review article › peer-review
130 Scopus citations -
Historical claims and current interpretations of replicative aging
Wright, W. E. & Shay, J. W., 2002, In: Nature biotechnology. 20, 7, p. 682-688 7 p.Research output: Contribution to journal › Review article › peer-review
303 Scopus citations -
Is there an antiaging medicine?
Butler, R. N., Fossel, M., Harman, S. M., Heward, C. B., Olshansky, S. J., Perls, T. T., Rothman, D. J., Rothman, S. M., Warner, H. R., West, M. D. & Wright, W. E., Sep 2002, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 57, 9, p. B333-B338Research output: Contribution to journal › Review article › peer-review
Open Access55 Scopus citations -
Telomerase: A target for cancer therapeutics
Shay, J. W. & Wright, W. E., Oct 2002, In: Cancer Cell. 2, 4, p. 257-265 9 p.Research output: Contribution to journal › Review article › peer-review
303 Scopus citations -
Telomerase and differentiation in multicellular organisms: Turn it off, turn it on, and turn it off again
Forsyth, N. R., Wright, W. E. & Shay, J. W., Jan 2002, In: Differentiation. 69, 4-5, p. 188-197 10 p.Research output: Contribution to journal › Review article › peer-review
298 Scopus citations -
Telomerase in cancer and aging
Granger, M. P., Wright, W. E. & Shay, J. W., 2002, In: Critical Reviews in Oncology/Hematology. 41, 1, p. 29-40 12 p.Research output: Contribution to journal › Review article › peer-review
140 Scopus citations -
Telomerase regulation: Not just flipping the switch
Aisner, D. L., Wright, W. E. & Shay, J. W., Feb 1 2002, In: Current Opinion in Genetics and Development. 12, 1, p. 80-85 6 p.Research output: Contribution to journal › Review article › peer-review
136 Scopus citations -
2001
Cellular senescence as a tumor-protection mechanism: The essential role of counting
Wright, W. E. & Shay, J. W., Feb 1 2001, In: Current Opinion in Genetics and Development. 11, 1, p. 98-103 6 p.Research output: Contribution to journal › Review article › peer-review
262 Scopus citations -
Forward: Aging and cancer: Are telomeres and telomerase the connection?
Shay, J. W. & Wright, W. E., 2001, In: Advances in Cell Aging and Gerontology. 8, C, p. 1-13 13 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Telomerase and cancer
Shay, J. W., Zou, Y., Hiyama, E. & Wright, W. E., 2001, In: Human molecular genetics. 10, 7, p. 677-685 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access362 Scopus citations -
Telomerase inhibitors
White, L. K., Wright, W. E. & Shay, J. W., Mar 1 2001, In: Trends in Biotechnology. 19, 3, p. 114-120 7 p.Research output: Contribution to journal › Review article › peer-review
200 Scopus citations -
2000
Hayflick, his limit, and cellular ageing
Shay, J. W. & Wright, W. E., Oct 2000, In: Nature Reviews Molecular Cell Biology. 1, 1, p. 72-76 5 p.Research output: Contribution to journal › Review article › peer-review
525 Scopus citations -
Implications of mapping the human telomerase gene (hTERT) as the most distal gene on chromosome 5p
Shay, J. W. & Wright, W. E., 2000, In: Neoplasia. 2, 3, p. 195-196 2 p.Research output: Contribution to journal › Review article › peer-review
Open Access26 Scopus citations -
Telomere dynamics in cancer progression and prevention: Fundamental differences in human and mouse telomere biology
Wright, W. E. & Shay, J. W., Aug 2000, In: Nature medicine. 6, 8, p. 849-851 3 p.Research output: Contribution to journal › Review article › peer-review
339 Scopus citations -
1996
Telomerase activity in human cancer
Shay, J. W. & Wright, W. E., 1996, In: Current Opinion in Oncology. 8, 1, p. 66-71 6 p.Research output: Contribution to journal › Review article › peer-review
393 Scopus citations -
Telomeres and telomerase: A simple picture becomes complex
Lundblad, V. & Wright, W. E., Nov 1 1996, In: Cell. 87, 3, p. 369-375 7 p.Research output: Contribution to journal › Review article › peer-review
86 Scopus citations -
1993
Loss of telomeric DNA during aging may predispose cells to cancer (review)
Shay, J. W., Wright, W. E. & Werbin, H., Jan 1 1993, In: International journal of oncology. 3, 4, p. 559-563 5 p.Research output: Contribution to journal › Review article › peer-review
45 Scopus citations -
1991
Molecular biology of myogenic regulatory factors
Funk, W. D., Ouellette, M. & Wright, W. E., Dec 1 1991, In: Molecular Biology and Medicine. 8, 2, p. 185-195 11 p.Research output: Contribution to journal › Review article › peer-review
34 Scopus citations -
1986
Cloning of muscle regulatory factors.
Wright, W. E., Dec 1 1986, In: Progress in clinical and biological research. 226, p. 455-465 11 p.Research output: Contribution to journal › Review article › peer-review
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1985
BUdR, probability and cell variants: Towards a molecular understanding of the decision to differentiate
Wright, W. E., Dec 1985, In: BioEssays. 3, 6, p. 245-248 4 p.Research output: Contribution to journal › Review article › peer-review
5 Scopus citations