Telomerase inhibitors

Laura K. White, Woodring E. Wright, Jerry W. Shay

Research output: Contribution to journalReview articlepeer-review

90 Scopus citations


There has been a vast increase in telomerase research over the past several years, with many different pre-clinical approaches being tested for inhibiting the activity of this enzyme as a novel therapeutic modality to treat malignancy. In this review, we will provide some basic background information about telomeres and telomerase and then discuss the pros, cons and challenges of the approaches that are currently under investigation, and what we might expect in the future of this emerging field.

Original languageEnglish (US)
Pages (from-to)114-120
Number of pages7
JournalTrends in Biotechnology
Issue number3
StatePublished - Mar 1 2001

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering


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