Abstract
Almost 40 years ago, Leonard Hayflick discovered that cultured normal human cells have limited capacity to divide, after which they become senescent - a phenomenon now known as the 'Hayflick limit'. Hayflick's findings were strongly challenged at the time, and continue to be questioned in a few circles, but his achievements have enabled others to make considerable progress towards understanding and manipulating the molecular mechanisms of ageing.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 72-76 |
| Number of pages | 5 |
| Journal | Nature Reviews Molecular Cell Biology |
| Volume | 1 |
| Issue number | 1 |
| DOIs | |
| State | Published - Oct 2000 |
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology