Research output per year
Research output per year
- 45 results
Search results
-
2024
Molecular determinants of lipid droplet subpopulations and their fates
Henne, W. M., 2024, (Accepted/In press) In: FEBS Letters.Research output: Contribution to journal › Article › peer-review
Open Access -
Tld1 is a regulator of triglyceride lipolysis that demarcates a lipid droplet subpopulation
Speer, N. O., Jay Braun, R., Reynolds, E. G., Brudnicka, A., Swanson, J. M. J. & Mike Henne, W., Jan 1 2024, In: Journal of Cell Biology. 223, 1, e202303026.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2023
The fat body cortical actin network regulates Drosophila inter-organ nutrient trafficking, signaling, and adipose cell size
Ugrankar-Banerjee, R., Tran, S., Bowerman, J., Kovalenko, A., Paul, B. & Henne, W. M., 2023, In: eLife. 12, e81170.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2022
An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma
Zhou, J., Simon, J. M., Liao, C., Zhang, C., Hu, L., Zurlo, G., Liu, X., Fan, C., Hepperla, A., Jia, L., Tcheuyap, V. T., Zhong, H., Elias, R., Ye, J., Henne, W. M., Kapur, P., Nijhawan, D., Brugarolas, J. & Zhang, Q., Aug 18 2022, In: Molecular cell. 82, 16, p. 3030-3044.e8Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
ER-localized phosphatidylethanolamine synthase plays a conserved role in lipid droplet formation
Gok, M. O., Speer, N. O., Henne, W. M. & Friedman, J. R., Jan 1 2022, In: Molecular biology of the cell. 33, 1, ar11.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Filling in the gaps: SNX-RGS proteins as multiorganelle tethers
Hariri, H. & Henne, W. M., May 2 2022, In: Journal of Cell Biology. 221, 5, e202203061.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Snazarus and its human ortholog SNX25 modulate autophagic flux
Lauzier, A., Bossanyi, M. F., Larcher, R., Nassari, S., Ugrankar, R., Henne, W. M. & Jean, S., 2022, In: Journal of cell science. 135, 5, jcs258733.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Structural Predictions of the SNX-RGS Proteins Suggest They Belong to a New Class of Lipid Transfer Proteins
Paul, B., Weeratunga, S., Tillu, V. A., Hariri, H., Henne, W. M. & Collins, B. M., Feb 3 2022, In: Frontiers in Cell and Developmental Biology. 10, 826688.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Triglyceride lipolysis triggers liquid crystalline phases in lipid droplets and alters the LD proteome
Rogers, S., Gui, L., Kovalenko, A., Zoni, V., Carpentier, M., Ramji, K., Mbarek, K. B., Bacle, A., Fuchs, P., Campomanes, P., Reetz, E., Speer, N. O., Reynolds, E., Thiam, A. R., Vanni, S., Nicastro, D. & Mike Henne, W., Nov 7 2022, In: Journal of Cell Biology. 221, 11, e202205053.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Vacuole-Specific Lipid Release for Tracking Intracellular Lipid Metabolism and Transport in Saccharomyces cerevisiae
Girik, V., Feng, S., Hariri, H., Henne, W. M. & Riezman, H., Jun 17 2022, In: ACS chemical biology. 17, 6, p. 1485-1494 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2021
Analysis of neutral lipid synthesis in saccharomyces cerevisiae by metabolic labeling and thin layer chromatography
Rogers, S. & Mike Henne, W., 2021, In: Journal of Visualized Experiments. 2021, 168, p. 1-9 9 p., e62201.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Glucose restriction drives spatial reorganization of mevalonate metabolism
Rogers, S., Hariri, H., Wood, N. E., Speer, N. O. & Henne, W. M., 2021, In: eLife. 10, e62591.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
How NPC1 Loss Twists the TORCque of Lysosomes
Henne, W. M., Feb 8 2021, In: Developmental cell. 56, 3, p. 251-252 2 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
How the vacuole escrts its own proteins to their final destination
Henne, W. M., Aug 2 2021, In: Journal of Cell Biology. 220, 8, e202105177.Research output: Contribution to journal › Article › peer-review
Open Access -
Organelle homeostasis principles: How organelle quality control and inter-organelle crosstalk promote cell survival
Henne, W. M., Apr 5 2021, In: Developmental cell. 56, 7, p. 878-880 3 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2020
Diverse species-specific phenotypic consequences of loss of function sorting nexin 14 mutations
Bryant, D., Seda, M., Peskett, E., Maurer, C., Pomeranz, G., Ghosh, M., Hawkins, T. A., Cleak, J., Datta, S., Hariri, H., Eckert, K. M., Jafree, D. J., Walsh, C., Demetriou, C., Ishida, M., Alemán-Charlet, C., Vestito, L., Seselgyte, R., McDonald, J. G., Bitner-Glindzicz, M., & 7 others, Dec 1 2020, In: Scientific reports. 10, 1, 13763.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Nutrient Signaling, Stress Response, and Inter-organelle Communication Are Non-canonical Determinants of Cell Fate
Wood, N. E., Kositangool, P., Hariri, H., Marchand, A. J. & Henne, W. M., Dec 1 2020, In: Cell Reports. 33, 9, 108446.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Snx14 proximity labeling reveals a role in saturated fatty acid metabolism and ER homeostasis defective in SCAR20 disease
Datta, S., Bowerman, J., Hariri, H., Ugrankar, R., Eckert, K. M., Corley, C., Vale, G., McDonald, J. G. & Mike Henne, W., Dec 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 52, p. 33282-33294 13 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2019
Cerebellar ataxia disease-associated Snx14 promotes lipid droplet growth at ER-droplet contacts
Datta, S., Liu, Y., Hariri, H., Bowerman, J. & Henne, W. M., 2019, In: Journal of Cell Biology. 218, 4, p. 1335-1351 17 p.Research output: Contribution to journal › Article › peer-review
Open Access80 Scopus citations -
Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities
Chandra, M., Chin, Y. K. Y., Mas, C., Feathers, J. R., Paul, B., Datta, S., Chen, K. E., Jia, X., Yang, Z., Norwood, S. J., Mohanty, B., Bugarcic, A., Teasdale, R. D., Henne, W. M., Mobli, M. & Collins, B. M., Dec 1 2019, In: Nature communications. 10, 1, 1528.Research output: Contribution to journal › Article › peer-review
Open Access87 Scopus citations -
Drosophila Snazarus Regulates a Lipid Droplet Population at Plasma Membrane-Droplet Contacts in Adipocytes
Ugrankar, R., Bowerman, J., Hariri, H., Chandra, M., Chen, K., Bossanyi, M. F., Datta, S., Rogers, S., Eckert, K. M., Vale, G., Victoria, A., Fresquez, J., McDonald, J. G., Jean, S., Collins, B. M. & Henne, W. M., Sep 9 2019, In: Developmental cell. 50, 5, p. 557-572.e5Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
Mdm1 maintains endoplasmic reticulum homeostasis by spatially regulating lipid droplet biogenesis
Hariri, H., Speer, N., Bowerman, J., Rogers, S., Fu, G., Reetz, E., Datta, S., Feathers, J. R., Ugrankar, R., Nicastro, D. & Henne, W. M., 2019, In: Journal of Cell Biology. 218, 4, p. 1319-1334 16 p.Research output: Contribution to journal › Article › peer-review
Open Access80 Scopus citations -
2018
Circulating glucose levels inversely correlate with Drosophila larval feeding through insulin signaling and SLC5A11
Ugrankar, R., Theodoropoulos, P., Akdemir, F., Henne, W. M. & Graff, J. M., Dec 1 2018, In: Communications Biology. 1, 1, 110.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Endoplasmic Reticulum-Vacuole Contact Sites “Bloom” With Stress-Induced Lipid Droplets
Henne, W. M. & Hariri, H., Jan 1 2018, In: Contact. 1Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Lipid droplet biogenesis is spatially coordinated at ER–vacuole contacts under nutritional stress
Hariri, H., Rogers, S., Ugrankar, R., Liu, Y. L., Feathers, J. R. & Henne, W. M., 2018, In: EMBO Reports. 19, 1, p. 57-72 16 p.Research output: Contribution to journal › Article › peer-review
Open Access123 Scopus citations -
Organelles in metabolism and stress responses
Ferguson, S. M. & Henne, W. M., Mar 15 2018, In: Molecular biology of the cell. 29, 6, p. 691 1 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
SNX14 mutations affect endoplasmic reticulumassociated neutral lipid metabolism in autosomal recessive spinocerebellar ataxia 20
Bryant, D., Liu, Y., Datta, S., Hariri, H., Seda, M., Anderson, G., Peskett, E., Demetriou, C., Sousa, S., Jenkins, D., Clayton, P., Bitner-Glindzicz, M., Moore, G. E., Henne, W. M. & Stanier, P., Jun 1 2018, In: Human molecular genetics. 27, 11, p. 1927-1940 14 p.Research output: Contribution to journal › Article › peer-review
Open Access50 Scopus citations -
2016
ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesis
Tang, S., Buchkovich, N. J., Mike Henne, W., Banjade, S., Kim, Y. J. & Emr, S. D., Apr 13 2016, In: eLife. 5, April 2016, e15507.Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations -
Organelle remodeling at membrane contact sites
Henne, W. M., Oct 1 2016, In: Journal of Structural Biology. 196, 1, p. 15-19 5 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
2015
Mdm1/Snx13 is a novel ER-endolysosomal interorganelle tethering protein
Henne, W. M., Zhu, L., Balogi, Z., Stefan, C., Pleiss, J. A. & Emr, S. D., Aug 17 2015, In: Journal of Cell Biology. 210, 4, p. 541-551 11 p.Research output: Contribution to journal › Article › peer-review
Open Access114 Scopus citations -
Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments
Tang, S., Henne, W. M., Borbat, P. P., Buchkovich, N. J., Freed, J. H., Mao, Y., Fromme, J. C. & Emr, S. D., Dec 15 2015, In: eLife. 4, DECEMBER2015, e12548.Research output: Contribution to journal › Article › peer-review
Open Access96 Scopus citations -
2013
Essential N-Terminal insertion motif anchors the ESCRT-III filament during MVB vesicle formation
Buchkovich, N. J., Henne, W. M., Tang, S. & Emr, S. D., Oct 28 2013, In: Developmental cell. 27, 2, p. 201-214 14 p.Research output: Contribution to journal › Article › peer-review
73 Scopus citations -
Molecular mechanisms of the membrane sculpting ESCRT pathway
Henne, W. M., Stenmark, H. & Emr, S. D., Oct 14 2013, In: Cold Spring Harbor Perspectives in Medicine. 3, 10, a016766.Research output: Contribution to journal › Article › peer-review
119 Scopus citations -
Molecular mechanisms of the membrane sculpting ESCRT pathway
Henne, W. M., Stenmark, H. & Emr, S. D., Sep 2013, In: Cold Spring Harbor Perspectives in Biology. 5, 9Research output: Contribution to journal › Article › peer-review
230 Scopus citations -
2012
PSTPIP2 deficiency in mice causes osteopenia and increased differentiation of multipotent myeloid precursors into osteoclasts
Chitu, V., Nacu, V., Charles, J. F., Henne, W. M., McMahon, H. T., Nandi, S., Ketchum, H., Harris, R., Nakamura, M. C. & Stanley, E. R., Oct 11 2012, In: Blood. 120, 15, p. 3126-3135 10 p.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations -
The endosomal sorting complex ESCRT-II mediates the assembly and architecture of ESCRT-III helices
Henne, W. M., Buchkovich, N. J., Zhao, Y. & Emr, S. D., Oct 12 2012, In: Cell. 151, 2, p. 356-371 16 p.Research output: Contribution to journal › Article › peer-review
168 Scopus citations -
2011
Intracellular curvature-generating proteins in cell-to-cell fusion
Richard, J. P., Leikina, E., Langen, R., Henne, W. M., Popova, M., Balla, T., Mcmahon, H. T., Kozlov, M. M. & Chernomordik, L. V., Dec 1 2011, In: Biochemical Journal. 440, 2, p. 185-193 9 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
2010
Dissecting BAR domain function in the yeast amphiphysins Rvs161 and Rvs167 during endocytosis
Youn, J. Y., Friesen, H., Kishimoto, T., Henne, W. M., Kurat, C. F., Ye, W., Ceccarelli, D. F., Sicheri, F., Kohlwein, S. D., McMahon, H. T. & Andrews, B. J., Sep 1 2010, In: Molecular biology of the cell. 21, 17, p. 3054-3069 16 p.Research output: Contribution to journal › Article › peer-review
Open Access62 Scopus citations -
FCHo proteins are nucleators of Clathrin-Mediated endocytosis
Henne, W. M., Boucrot, E., Meinecke, M., Evergren, E., Vallis, Y., Mittal, R. & McMahon, H. T., Jun 4 2010, In: Science. 328, 5983, p. 1281-1284 4 p.Research output: Contribution to journal › Article › peer-review
345 Scopus citations -
2008
AMPA-induced dark cell degeneration is associated with activation of caspases in pyramidal neurons of the rat hippocampus
Coles, J., Oomman, S. K., Henne, W. M., Bliss, R. M., Hoffman, T. C., Finckbone, V., Strahlendorf, H. & Strahlendorf, J., May 16 2008, In: Neuroscience letters. 436, 3, p. 294-299 6 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
2007
Involvement of calpain in AMPA-induced toxicity to rat cerebellar Purkinje neurons
Mansouri, B., Henne, W. M., Oomman, S. K., Bliss, R., Attridge, J., Finckbone, V., Zeitouni, T., Hoffman, T., Bahr, B. A., Strahlendorf, H. K. & Strahlendorf, J. C., Feb 28 2007, In: European Journal of Pharmacology. 557, 2-3, p. 106-114 9 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
Structure and Analysis of FCHo2 F-BAR Domain: A Dimerizing and Membrane Recruitment Module that Effects Membrane Curvature
Henne, W. M., Kent, H. M., Ford, M. G. J., Hegde, B. G., Daumke, O., Butler, P. J. G., Mittal, R., Langen, R., Evans, P. R. & McMahon, H. T., Jul 18 2007, In: Structure. 15, 7, p. 839-852 14 p.Research output: Contribution to journal › Article › peer-review
237 Scopus citations -
2006
AMPA-induced excitotoxicity increases nuclear levels of CAD, Endonuclease G, and acinus and induces chromatin condensation in rat hippocampal pyramidal neurons
Henne, W. M., Oomman, S., Attridge, J., Finckbone, V., Coates, P., Bliss, R., Strahlendorf, H. & Strahlendorf, J., May 2006, In: Cellular and Molecular Neurobiology. 26, 3, p. 321-339 19 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
2004
Active caspase-3 expression during postnatal development of rat cerebellum is not systematically or consistently associated with apoptosis
Oomman, S., Finckbone, V., Dertien, J., Attridge, J., Henne, W., Medina, M., Mansouri, B., Singh, H., Strahlendorf, H. & Strahlendorf, J., Aug 16 2004, In: Journal of Comparative Neurology. 476, 2, p. 154-173 20 p.Research output: Contribution to journal › Article › peer-review
52 Scopus citations -
2003
AMPA-induced dark cell degeneration of cerebellar Purkinje neurons involves activation of caspases and apparent mitochondrial dysfunction
Strahlendorf, J., Box, C., Attridge, J., Diertien, J., Finckbone, V., Henne, W. M., Medina, M. S., Miles, R., Oomman, S., Schneider, M., Singh, H., Veliyaparabil, M. & Strahlendorf, H., Dec 24 2003, In: Brain Research. 994, 2, p. 146-159 14 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations