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1996 …2024

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  • Apoptotic cell death in disease—Current understanding of the NCCD 2023

    Vitale, I., Pietrocola, F., Guilbaud, E., Aaronson, S. A., Abrams, J. M., Adam, D., Agostini, M., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Aqeilan, R. I., Arama, E., Baehrecke, E. H., Balachandran, S., Bano, D., Barlev, N. A., Bartek, J., Bazan, N. G., & 208 othersBecker, C., Bernassola, F., Bertrand, M. J. M., Bianchi, M. E., Blagosklonny, M. V., Blander, J. M., Blandino, G., Blomgren, K., Borner, C., Bortner, C. D., Bove, P., Boya, P., Brenner, C., Broz, P., Brunner, T., Damgaard, R. B., Calin, G. A., Campanella, M., Candi, E., Carbone, M., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chen, G. Q., Chen, Q., Chen, Y. H., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Ciliberto, G., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D’Angiolella, V., Daugaard, M., Dawson, T. M., Dawson, V. L., De Maria, R., De Strooper, B., Debatin, K. M., Deberardinis, R. J., Degterev, A., Del Sal, G., Deshmukh, M., Di Virgilio, F., Diederich, M., Dixon, S. J., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Engeland, K., Fimia, G. M., Galassi, C., Ganini, C., Garcia-Saez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Gerlic, M., Ghosh, S., Green, D. R., Greene, L. A., Gronemeyer, H., Häcker, G., Hajnóczky, G., Hardwick, J. M., Haupt, Y., He, S., Heery, D. M., Hengartner, M. O., Hetz, C., Hildeman, D. A., Ichijo, H., Inoue, S., Jäättelä, M., Janic, A., Joseph, B., Jost, P. J., Kanneganti, T. D., Karin, M., Kashkar, H., Kaufmann, T., Kelly, G. L., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Kluck, R., Krysko, D. V., Kulms, D., Kumar, S., Lavandero, S., Lavrik, I. N., Lemasters, J. J., Liccardi, G., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Luedde, T., MacFarlane, M., Madeo, F., Malorni, W., Manic, G., Mantovani, R., Marchi, S., Marine, J. C., Martin, S. J., Martinou, J. C., Mastroberardino, P. G., Medema, J. P., Mehlen, P., Meier, P., Melino, G., Melino, S., Miao, E. A., Moll, U. M., Muñoz-Pinedo, C., Murphy, D. J., Niklison-Chirou, M. V., Novelli, F., Núñez, G., Oberst, A., Ofengeim, D., Opferman, J. T., Oren, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pentimalli, F., Pereira, D. M., Pervaiz, S., Peter, M. E., Pinton, P., Porta, G., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rajalingam, K., Ravichandran, K. S., Rehm, M., Ricci, J. E., Rizzuto, R., Robinson, N., Rodrigues, C. M. P., Rotblat, B., Rothlin, C. V., Rubinsztein, D. C., Rudel, T., Rufini, A., Ryan, K. M., Sarosiek, K. A., Sawa, A., Sayan, E., Schroder, K., Scorrano, L., Sesti, F., Shao, F., Shi, Y., Sica, G. S., Silke, J., Simon, H. U., Sistigu, A., Stephanou, A., Stockwell, B. R., Strapazzon, F., Strasser, A., Sun, L., Sun, E., Sun, Q., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Troy, C. M., Turk, B., Urbano, N., Vandenabeele, P., Vanden Berghe, T., Vander Heiden, M. G., Vanderluit, J. L., Verkhratsky, A., Villunger, A., von Karstedt, S., Voss, A. K., Vousden, K. H., Vucic, D., Vuri, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, R., Wang, Y., Weber, A., Wood, W., Yamazaki, T., Yang, H. T., Zakeri, Z., Zawacka-Pankau, J. E., Zhang, L., Zhang, H., Zhivotovsky, B., Zhou, W., Piacentini, M., Kroemer, G. & Galluzzi, L., May 2023, In: Cell Death and Differentiation. 30, 5, p. 1097-1154 58 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    69 Scopus citations
  • Applications of metabolomics to study cancer metabolism

    Kaushik, A. K. & DeBerardinis, R. J., Aug 2018, In: Biochimica et Biophysica Acta - Reviews on Cancer. 1870, 1, p. 2-14 13 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    129 Scopus citations
  • A roadmap for interpreting 13C metabolite labeling patterns from cells

    Buescher, J. M., Antoniewicz, M. R., Boros, L. G., Burgess, S. C., Brunengraber, H., Clish, C. B., DeBerardinis, R. J., Feron, O., Frezza, C., Ghesquiere, B., Gottlieb, E., Hiller, K., Jones, R. G., Kamphorst, J. J., Kibbey, R. G., Kimmelman, A. C., Locasale, J. W., Lunt, S. Y., Maddocks, O. D. K., Malloy, C., & 17 othersMetallo, C. M., Meuillet, E. J., Munger, J., Nöh, K., Rabinowitz, J. D., Ralser, M., Sauer, U., Stephanopoulos, G., St-Pierre, J., Tennant, D. A., Wittmann, C., Vander Heiden, M. G., Vazquez, A., Vousden, K., Young, J. D., Zamboni, N. & Fendt, S. M., Aug 1 2015, In: Current Opinion in Biotechnology. 34, p. 189-201 13 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    439 Scopus citations
  • Autophagy in metazoans: Cell survival in the land of plenty

    Lum, J. J., DeBerardinis, R. J. & Thompson, C. B., Jun 2005, In: Nature Reviews Molecular Cell Biology. 6, 6, p. 439-448 10 p.

    Research output: Contribution to journalReview articlepeer-review

    669 Scopus citations
  • Brick by brick: metabolism and tumor cell growth

    DeBerardinis, R. J., Sayed, N., Ditsworth, D. & Thompson, C. B., Feb 2008, In: Current Opinion in Genetics and Development. 18, 1, p. 54-61 8 p.

    Research output: Contribution to journalReview articlepeer-review

    836 Scopus citations
  • Cellular metabolism and disease: What do metabolic outliers teach us?

    Deberardinis, R. J. & Thompson, C. B., Mar 16 2012, In: Cell. 148, 6, p. 1132-1144 13 p.

    Research output: Contribution to journalReview articlepeer-review

    624 Scopus citations
  • Designing a broad-spectrum integrative approach for cancer prevention and treatment

    Block, K. I., Gyllenhaal, C., Lowe, L., Amedei, A., Ruhul Amin, A. R. M., Amin, A., Aquilano, K., Arbiser, J., Arreola, A., Arzumanyan, A., Salman Ashraf, S., Azmi, A. S., Benencia, F., Bhakta, D., Bilsland, A., Bishayee, A., Blain, S. W., Block, P. B., Boosani, C. S., Carey, T. E., & 160 othersCarnero, A., Carotenuto, M., Casey, S. C., Chakrabarti, M., Chaturvedi, R., Chen, G. Z., Chen, H., Chen, S., Chen, Y. C., Choi, B. K., Ciriolo, M. R., Coley, H. M., Collins, A. R., Connell, M., Crawford, S., Curran, C. S., Dabrosin, C., Damia, G., Dasgupta, S., DeBerardinis, R. J., Decker, W. K., Dhawan, P., Diehl, A. M. E., Dong, J. T., Dou, Q. P., Drewa, J. E., Elkord, E., El-Rayes, B., Feitelson, M. A., Felsheru, D. W., Ferguson, L. R., Fimognari, C., Firestone, G. L., Frezza, C., Fujii, H., Fuster, M. M., Generali, D., Georgakilas, A. G., Gieseler, F., Gilbertson, M., Green, M. F., Grue, B., Guhal, G., Halicka, D., Helferich, W. G., Heneberg, P., Hentosh, P., Hirschey, M. D., Hofseth, L. J., Holcombe, R. F., Honoki, K., Hsu, H. Y., Huang, G. S., Jensen, L. D., Jiang, W. G., Jones, L. W., Karpowicz, P. A., Keith, W. N., Kerkar, S. P., Khan, G. N., Khatami, M., Ko, Y. H., Kucuk, O., Kulathinal, R. J., Kumar, N. B., Kwon, B. S., Leb, A., Leab, M. A., Lee, H. Y., Lichtor, T., Lin, L. T., Locasale, J. W., Lokeshwar, B. L., Longo, V. D., Lyssiotis, C. A., MacKenzie, K. L., Malhotra, M., Marino, M., Martinez-Chantar, M. L., Matheu, A., Maxwellx, C., McDonnell, E., Meeker, A. K., Mehrmohamadi, M., Mehta, K., Michelotti, G. A., Mohammad, R. M., Mohammed, S. I., Morre, D. J., Muqbil, I., Muralidharcq, V., Murphy, M. P., Nagaraju, G. P., Nahta, R., Niccolai, E., Nowsheen, S., Panis, C., Pantano, F., Parslow, V. R., Pawelec, G., Pedersen, P. L., Poore, B., Poudyal, D., Prakash, S., Prince, M., Raffaghello, L., Rathmell, J. C., Rathmell, W. K., Ray, S. K., Reichrath, J., Rezazadeh, S., Ribatti, D., Ricciardiello, L., Robeydf, R. B., Rodierdh, F., Rupasinghe, H. P. V., Russo, G. L., Ryan, E. P., Samadi, A. K., Sanchez-Garcia, I., Sanders, A. J., Santini, D., Sarkar, M., Sasada, T., Saxena, N. K., Shackelford, R. E., Shantha Kumara, H. M. C., Sharma, D., Shin, D. M., Sidransky, D., Siegelin, M. D., Signori, E., Singh, N., Sivanand, S., Sliva, D., Smythe, C., Spagnuolo, C., Stafforini, D. M., Stagg, J., Subbarayan, P. R., Sundin, T., Talib, W. H., Thompson, S. K., Tran, P. T., Ungefroren, H., Vander Heiden, M. G., Venkateswaran, V., Vinay, D. S., Vlachostergios, P. J., Wang, Z., Wellen, K. E., Whelan, R. L., Yang, E. S., Yang, H., Yang, X., Yaswen, P., Yedjou, C., Yin, X., Zhu, J. & Zollo, M., 2015, In: Seminars in Cancer Biology. 35, p. S276-S304

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    250 Scopus citations
  • DiGeorge anomaly in a patient with isochromosome 18p born to a diabetic mother

    DeBerardinis, R. J., Medne, L., Spinner, N. B. & Zackai, E. H., Oct 1 2005, In: American Journal of Medical Genetics. 138 A, 2, p. 155-159 5 p.

    Research output: Contribution to journalReview articlepeer-review

    7 Scopus citations
  • Dysregulated metabolism contributes to oncogenesis

    Target Validation Team, Dec 1 2015, In: Seminars in Cancer Biology. 35, p. S129-S150

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    219 Scopus citations
  • Fundamentals of cancer metabolism

    DeBerardinis, R. J. & Chandel, N. S., May 2016, In: Science Advances. 2, 5, e1600200.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    1856 Scopus citations
  • Genetically-defined metabolic reprogramming in cancer

    Mullen, A. R. & DeBerardinis, R. J., Nov 2012, In: Trends in Endocrinology and Metabolism. 23, 11, p. 552-559 8 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    67 Scopus citations
  • Glutamine: Pleiotropic roles in tumor growth and stress resistance

    Shanware, N. P., Mullen, A. R., DeBerardinis, R. J. & Abraham, R. T., Mar 2011, In: Journal of Molecular Medicine. 89, 3, p. 229-236 8 p.

    Research output: Contribution to journalReview articlepeer-review

    153 Scopus citations
  • Glutamine and cancer: Cell biology, physiology, and clinical opportunities

    Hensley, C. T., Wasti, A. T. & DeBerardinis, R. J., Sep 3 2013, In: Journal of Clinical Investigation. 123, 9, p. 3678-3684 7 p.

    Research output: Contribution to journalReview articlepeer-review

    933 Scopus citations
  • In vivo analysis of lung cancer metabolism: Nothing like the real thing

    Hensley, C. T. & De Berardinis, R. J., Feb 2 2015, In: Journal of Clinical Investigation. 125, 2, p. 495-497 3 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    17 Scopus citations
  • Is cancer a disease of abnormal cellular metabolism? New angles on an old idea

    DeBerardinis, R. J., Nov 2008, In: Genetics in Medicine. 10, 11, p. 767-777 11 p.

    Research output: Contribution to journalReview articlepeer-review

    173 Scopus citations
  • Lipoic acid metabolism and mitochondrial redox regulation

    Solmonson, A. & DeBerardinis, R. J., May 18 2018, In: Journal of Biological Chemistry. 293, 20, p. 7522-7530 9 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    220 Scopus citations
  • Mechanisms and Implications of Metabolic Heterogeneity in Cancer

    Kim, J. & DeBerardinis, R. J., Sep 3 2019, In: Cell Metabolism. 30, 3, p. 434-446 13 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    325 Scopus citations
  • Metabolic analysis as a driver for discovery, diagnosis, and therapy

    DeBerardinis, R. J. & Keshari, K. R., Jul 21 2022, In: Cell. 185, 15, p. 2678-2689 12 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    51 Scopus citations
  • Metabolic dysregulation in monogenic disorders and cancer-finding method in madness

    Erez, A. & Deberardinis, R. J., Jul 26 2015, In: Nature Reviews Cancer. 15, 7, p. 440-448 9 p.

    Research output: Contribution to journalReview articlepeer-review

    84 Scopus citations
  • Metabolic pathway analysis using stable isotopes in patients with cancer

    Bartman, C. R., Faubert, B., Rabinowitz, J. D. & DeBerardinis, R. J., Dec 2023, In: Nature Reviews Cancer. 23, 12, p. 863-878 16 p.

    Research output: Contribution to journalReview articlepeer-review

    5 Scopus citations
  • Metabolic pathways promoting cancer cell survival and growth

    Boroughs, L. K. & Deberardinis, R. J., Apr 30 2015, In: Nature cell biology. 17, 4, p. 351-359 9 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    1043 Scopus citations
  • Metabolic Plasticity of Neutrophils: Relevance to Pathogen Responses and Cancer

    Rogers, T. & DeBerardinis, R. J., Aug 2021, In: Trends in Cancer. 7, 8, p. 700-713 14 p.

    Research output: Contribution to journalReview articlepeer-review

    28 Scopus citations
  • Metabolic reprogramming and cancer progression

    Faubert, B., Solmonson, A. & DeBerardinis, R. J., Apr 10 2020, In: Science. 368, 6487, eaaw5473.

    Research output: Contribution to journalReview articlepeer-review

    962 Scopus citations
  • Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications

    Fischer, G. M., Vashisht Gopal, Y. N., McQuade, J. L., Peng, W., DeBerardinis, R. J. & Davies, M. A., Jan 2018, In: Pigment Cell and Melanoma Research. 31, 1, p. 11-30 20 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    123 Scopus citations
  • Molecular mechanisms of cell death: Recommendations of the Nomenclature Committee on Cell Death 2018

    Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Annicchiarico-Petruzzelli, M., Antonov, A. V., Arama, E., Baehrecke, E. H., Barlev, N. A., Bazan, N. G., Bernassola, F., Bertrand, M. J. M., Bianchi, K., Blagosklonny, M. V., & 149 othersBlomgren, K., Borner, C., Boya, P., Brenner, C., Campanella, M., Candi, E., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Cohen, G. M., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D'Angiolella, V., Dawson, T. M., Dawson, V. L., De Laurenzi, V., De Maria, R., Debatin, K. M., Deberardinis, R. J., Deshmukh, M., Di Daniele, N., Di Virgilio, F., Dixit, V. M., Dixon, S. J., Duckett, C. S., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Fimia, G. M., Fulda, S., García-Sáez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Golstein, P., Gottlieb, E., Green, D. R., Greene, L. A., Gronemeyer, H., Gross, A., Hajnoczky, G., Hardwick, J. M., Harris, I. S., Hengartner, M. O., Hetz, C., Ichijo, H., Jäättelä, M., Joseph, B., Jost, P. J., Juin, P. P., Kaiser, W. J., Karin, M., Kaufmann, T., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Knight, R. A., Kumar, S., Lee, S. W., Lemasters, J. J., Levine, B., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Lowe, S. W., Luedde, T., Lugli, E., MacFarlane, M., Madeo, F., Malewicz, M., Malorni, W., Manic, G., Marine, J. C., Martin, S. J., Martinou, J. C., Medema, J. P., Mehlen, P., Meier, P., Melino, S., Miao, E. A., Molkentin, J. D., Moll, U. M., Muñoz-Pinedo, C., Nagata, S., Nuñez, G., Oberst, A., Oren, M., Overholtzer, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pereira, D. M., Pervaiz, S., Peter, M. E., Piacentini, M., Pinton, P., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rehm, M., Rizzuto, R., Rodrigues, C. M. P., Rubinsztein, D. C., Rudel, T., Ryan, K. M., Sayan, E., Scorrano, L., Shao, F., Shi, Y., Silke, J., Simon, H. U., Sistigu, A., Stockwell, B. R., Strasser, A., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Thorburn, A., Tsujimoto, Y., Turk, B., Vanden Berghe, T., Vandenabeele, P., Vander Heiden, M. G., Villunger, A., Virgin, H. W., Vousden, K. H., Vucic, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, Y., Wells, J. A., Wood, W., Yuan, J., Zakeri, Z., Zhivotovsky, B., Zitvogel, L., Melino, G. & Kroemer, G., Mar 1 2018, In: Cell Death and Differentiation. 25, 3, p. 486-541 56 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    3886 Scopus citations
  • Q's next: The diverse functions of glutamine in metabolism, cell biology and cancer

    Deberardinis, R. J. & Cheng, T., Jan 2010, In: Oncogene. 29, 3, p. 313-324 12 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    1002 Scopus citations
  • Role of glutamine in cancer: Therapeutic and imaging implications

    Rajagopalan, K. N. & DeBerardinis, R. J., Jul 1 2011, In: Journal of Nuclear Medicine. 52, 7, p. 1005-1008 4 p.

    Research output: Contribution to journalReview articlepeer-review

    99 Scopus citations
  • Stable isotope tracing to assess tumor metabolism in vivo

    Faubert, B., Tasdogan, A., Morrison, S. J., Mathews, T. P. & DeBerardinis, R. J., Nov 2021, In: Nature Protocols. 16, 11, p. 5123-5145 23 p.

    Research output: Contribution to journalReview articlepeer-review

    32 Scopus citations
  • The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

    DeBerardinis, R. J., Lum, J. J., Hatzivassiliou, G. & Thompson, C. B., Jan 9 2008, In: Cell Metabolism. 7, 1, p. 11-20 10 p.

    Research output: Contribution to journalReview articlepeer-review

    3124 Scopus citations
  • Understanding the Intersections between Metabolism and Cancer Biology

    Vander Heiden, M. G. & DeBerardinis, R. J., Feb 9 2017, In: Cell. 168, 4, p. 657-669 13 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    1408 Scopus citations