Research output per year
Research output per year
- 1 - 50 out of 97 results
Search results
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2021
TMEM16F and dynamins control expansive plasma membrane reservoirs
Deisl, C., Hilgemann, D. W., Syeda, R. & Fine, M., Dec 1 2021, In: Nature communications. 12, 1, 4990.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2020
Control of cardiac contraction by sodium: Promises, reckonings, and new beginnings
Hilgemann, D. W., Jan 2020, In: Cell Calcium. 85, 102129.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Spatiotemporal regulation of NADP(H) phosphatase Nocturnin and its role in oxidative stress response
Laothamatas, I., Gao, P., Wickramaratne, A., Quintanilla, C. G., Dino, A., Khan, C. A., Liou, J. & Green, C. B., Jan 14 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 2, p. 993-999 7 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
2019
Hypertrophy of human embryonic stem cell–derived cardiomyocytes supported by positive feedback between Ca2+ and diacylglycerol signals
Deisl, C., Fine, M., Moe, O. W. & Hilgemann, D. W., Aug 1 2019, In: Pflugers Archiv European Journal of Physiology. 471, 8, p. 1143-1157 15 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Myristoylation-Dependent Palmitoylation of the Receptor Tyrosine Kinase Adaptor FRS2α
Barylko, B., Chen, Y. J., Hennen, J., Angert, I., Chen, Y., Mueller, J. D., Sun, H. Q., Taylor, C. A., Liou, J., Yin, H. & Albanesi, J. P., Jun 25 2019, In: Biochemistry. 58, 25, p. 2809-2813 5 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death
Wu, J., Chen, Y. J., Dobbs, N., Sakai, T., Liou, J., Miner, J. J. & Yan, N., Apr 1 2019, In: Journal of Experimental Medicine. 216, 4, p. 867-883 17 p.Research output: Contribution to journal › Article › peer-review
Open Access172 Scopus citations -
TMEM16F activation by Ca2+ triggers plasma membrane expansion and directs PD-1 trafficking
Bricogne, C., Fine, M., Pereira, P. M., Sung, J., Tijani, M., Wang, Y., Henriques, R., Collins, M. K. & Hilgemann, D., Dec 1 2019, In: Scientific reports. 9, 1, 619.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
2018
EB1 binding restricts STIM1 translocation to ER-PM junctions and regulates store-operated Ca2+ entry
Chang, C. L., Chen, Y. J., Quintanilla, C. G., Hsieh, T. S. & Liou, J., Jun 1 2018, In: Journal of Cell Biology. 217, 6, p. 2047-2058 12 p.Research output: Contribution to journal › Article › peer-review
Open Access53 Scopus citations -
Lipid signaling to membrane proteins: From second messengers to membrane domains and adapter-free endocytosis
Hilgemann, D. W., Dai, G., Collins, A., Lariccia, V., Magi, S., Deisl, C. & Fine, M., Feb 1 2018, In: Journal of General Physiology. 150, 2, p. 211-224 14 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Structural analyses of FERM domain-mediated membrane localization of FARP1
Kuo, Y. C., He, X., Coleman, A. J., Chen, Y. J., Dasari, P., Liou, J., Biederer, T. & Zhang, X., Dec 1 2018, In: Scientific reports. 8, 1, 10477.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
2017
Cortical actin contributes to spatial organization of ER-PM junctions
Hsieh, T. S., Chen, Y. J., Chang, C. L., Lee, W. R. & Liou, J., Nov 7 2017, In: Molecular biology of the cell. 28, 23, p. 3171-3180 10 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Na/K pump inactivation, subsarcolemmal Na measurements, and cytoplasmic ion turnover kinetics contradict restricted Na spaces in murine cardiac myocytes
Lu, F. M. & Hilgemann, D. W., Jul 1 2017, In: Journal of General Physiology. 149, 7, p. 727-749 23 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
RAS SF4 controls SOCE and ER-PM junctions through regulation of PI(4,5)P2
Chen, Y. J., Chang, C. L., Lee, W. R. & Liou, J., Jul 1 2017, In: Journal of Cell Biology. 216, 7, p. 2011-2025 15 p.Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
Soluble klotho binds monosialoganglioside to regulate membrane microdomains and growth factor signaling
Dalton, G., An, S. W., Al-Juboori, S. I., Nischan, N., Yoon, J., Dobrinskikh, E., Hilgemann, D. W., Xie, J., Luby-Phelps, K., Kohler, J. J., Birnbaumer, L. & Huang, C. L., Jan 24 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 4, p. 752-757 6 p.Research output: Contribution to journal › Article › peer-review
Open Access66 Scopus citations -
2016
Profound regulation of Na/K pump activity by transient elevations of cytoplasmic calcium in murine cardiac myocytes
Lu, F. M., Deisl, C. & Hilgemann, D. W., 2016, In: eLife. 5, e19267.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
S-palmitoylation and the regulation of NCX1
Fuller, W., Reilly, L. & Hilgemann, D. W., Jan 1 2016, In: Channels. 10, 2, p. 75-77 3 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
2015
A micropeptide encoded by a putative long noncoding RNA regulates muscle performance
Anderson, D. M., Anderson, K. M., Chang, C. L., Makarewich, C. A., Nelson, B. R., McAnally, J. R., Kasaragod, P., Shelton, J. M., Liou, J., Bassel-Duby, R. & Olson, E. N., Feb 12 2015, In: Cell. 160, 4, p. 595-606 12 p.Research output: Contribution to journal › Article › peer-review
862 Scopus citations -
Palmitoylation of the Na/Ca exchanger cytoplasmic loop controls its inactivation and internalization during stress signaling
Reilly, L., Howie, J., Wypijewski, K., Ashford, M. L. J., Hilgemann, D. W. & Fuller, W., Nov 1 2015, In: FASEB Journal. 29, 11, p. 4532-4543 12 p.Research output: Contribution to journal › Article › peer-review
Open Access53 Scopus citations -
Phosphatidylinositol 4, 5-bisphosphate homeostasis regulated by Nir2 and Nir3 proteins at endoplasmic reticulum-plasma membrane junctions
Chang, C. L. & Liou, J., Jun 5 2015, In: Journal of Biological Chemistry. 290, 23, p. 14289-14301 13 p.Research output: Contribution to journal › Article › peer-review
96 Scopus citations -
2013
Feedback regulation of receptor-induced ca2+ signaling mediated by e-syt1 and nir2 at endoplasmic reticulum-plasma membrane junctions
Chang, C. L., Hsieh, T. S., Yang, T. T., Rothberg, K. G., Azizoglu, D. B., Volk, E., Liao, J. C. & Liou, J., 2013, In: Cell Reports. 5, 3, p. 813-825 13 p.Research output: Contribution to journal › Article › peer-review
238 Scopus citations -
Human-induced pluripotent stem cell-derived cardiomyocytes for studies of cardiac ion transporters
Fine, M., Lu, F. M., Lin, M. J., Moe, O., Wang, H. R. & Hilgemann, D. W., Sep 1 2013, In: American Journal of Physiology - Cell Physiology. 305, 5, p. C481-C491Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
Massive endocytosis triggered by surface membrane palmitoylation under mitochondrial control in BHK fibroblasts
Hilgmann, D. W., Fine, M., Linder, M. E., Jennings, B. C. & Lin, M. J., Nov 26 2013, In: eLife. 2013, 2, e01293.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
Massive palmitoylation-dependent endocytosis during reoxygenation of anoxic cardiac muscle
Lin, M. J., Fine, M., Lu, J. Y., Hofmann, S. L., Frazier, G. & Hilgemann, D. W., Nov 26 2013, In: eLife. 2013, 2, e01295.Research output: Contribution to journal › Article › peer-review
60 Scopus citations -
2011
Massive calcium-activated endocytosis without involvement of classical endocytic proteins
Lariccia, V., Fine, M., Magi, S., Lin, M. J., Yaradanakul, A., Llaguno, M. C. & Hilgemann, D. W., Jan 2011, In: Journal of General Physiology. 137, 1, p. 111-132 22 p.Research output: Contribution to journal › Article › peer-review
82 Scopus citations -
Massive endocytosis driven by lipidic forces originating in the outer plasmalemmal monolayer: A new approach to membrane recycling and lipid domains
Fine, M., Llaguno, M. C., Lariccia, V., Lin, M. J., Yaradanakul, A. & Hilgemann, D. W., Feb 2011, In: Journal of General Physiology. 137, 2, p. 137-154 18 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
Mechanistic analysis of massive endocytosis in relation to functionally defned surface membrane domains
Hilgemann, D. W. & Fine, M., Feb 2011, In: Journal of General Physiology. 137, 2, p. 155-172 18 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development
Limnander, A., Depeille, P., Freedman, T. S., Liou, J., Leitges, M., Kurosaki, T., Roose, J. P. & Weiss, A., May 2011, In: Nature immunology. 12, 5, p. 425-433 9 p.Research output: Contribution to journal › Article › peer-review
Open Access105 Scopus citations -
2008
Ca-dependent nonsecretory vesicle fusion in a secretory cell
Wang, T. M. & Hilgemann, D. W., Jul 2008, In: Journal of General Physiology. 132, 1, p. 51-65 15 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
Massive Ca-induced membrane fusion and phospholipid changes triggered by reverse Na/Ca exchange in BHK fibroblasts
Yaradanakul, A., Wang, T. M., Lariccia, V., Lin, M. J., Shen, C., Liu, X. & Hilgemann, D. W., Jul 2008, In: Journal of General Physiology. 132, 1, p. 29-50 22 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
Steady-state function of the ubiquitous mammalian Na/H exchanger (NHE1) in relation to dimer coupling models with 2Na/2H stoichiometry
Fuster, D., Moe, O. W. & Hilgemann, D. W., Oct 2008, In: Journal of General Physiology. 132, 4, p. 465-480 16 p.Research output: Contribution to journal › Article › peer-review
48 Scopus citations -
2007
Dual control of cardiac Na+-Ca2+ exchange by PIP2: Analysis of the surface membrane fraction by extracellular cysteine PEGylation
Shen, C., Lin, M. J., Yaradanakul, A., Lariccia, V., Hill, J. A. & Hilgemann, D. W., Aug 1 2007, In: Journal of Physiology. 582, 3, p. 1011-1026 16 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Dual control of cardiac Na+-Ca2+ exchange by PIP2: Electrophysiological analysis of direct and indirect mechanisms
Yaradanakul, A., Feng, S., Shen, C., Lariccia, V., Lin, M. J., Yang, J., Dong, P., Yin, H. L., Albanesi, J. P. & Hilgemann, D. W., Aug 1 2007, In: Journal of Physiology. 582, 3, p. 991-1010 20 p.Research output: Contribution to journal › Article › peer-review
Open Access53 Scopus citations -
Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion
Liou, J., Fivaz, M., Inoue, T. & Meyer, T., May 29 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 22, p. 9301-9306 6 p.Research output: Contribution to journal › Article › peer-review
540 Scopus citations -
On the physiological roles of PIP2 at cardiac Na+- Ca2+ exchangers and KATP channels: A long journey from membrane biophysics into cell biology
Hilgemann, D. W., Aug 1 2007, In: Journal of Physiology. 582, 3, p. 903-909 7 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
siRNA screen of the human signaling proteome identifies the PtdIns(3,4,5)P3-mTOR signaling pathway as a primary regulator of transferrin uptake
Galvez, T., Teruel, M. N., Heo, W. D., Jones, J. T., Kim, M. L., Liou, J., Myers, J. W. & Meyer, T., Jul 19 2007, In: Genome biology. 8, 7, R142.Research output: Contribution to journal › Article › peer-review
48 Scopus citations -
STIM2 Is a Feedback Regulator that Stabilizes Basal Cytosolic and Endoplasmic Reticulum Ca2+ Levels
Brandman, O., Liou, J., Park, W. S. & Meyer, T., Dec 28 2007, In: Cell. 131, 7, p. 1327-1339 13 p.Research output: Contribution to journal › Article › peer-review
576 Scopus citations -
Unrestricted diffusion of exogenous and endogenous PIP2 in baby hamster kidney and Chinese hamster ovary cell plasmalemma
Yaradanakul, A. & Hilgemann, D. W., Dec 2007, In: Journal of Membrane Biology. 220, 1-3, p. 53-67 15 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
2006
Angiotensin II regulates neuronal excitability via phosphatidylinositol 4,5-bisphosphate-dependent modulation of Kv7 (M-type) K+ channels
Zaika, O., Lara, L. S., Gamper, N., Hilgemann, D. W., Jaffe, D. B. & Shapiro, M. S., Aug 2006, In: Journal of Physiology. 575, 1, p. 49-67 19 p.Research output: Contribution to journal › Article › peer-review
Open Access79 Scopus citations -
Molecular control of cardiac sodium homeostasis in health and disease
Hilgemann, D. W., Yaradanakul, A., Wang, Y. & Fuster, D., May 2006, In: Journal of Cardiovascular Electrophysiology. 17, SUPPL. 1, p. S47-S56Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
2005
Phospholipase C in living cells: Activation, inhibition, Ca2+ requirement, and regulation of M current
Horowitz, L. F., Hirdes, W., Suh, B. C., Hilgemann, D. W., Mackie, K. & Hille, B., Sep 2005, In: Journal of General Physiology. 126, 3, p. 243-262 20 p.Research output: Contribution to journal › Article › peer-review
275 Scopus citations -
Regulation of Kv7 (KCNQ) K+ channel open probability by phosphatidylinositol 4,5-bisphosphate
Li, Y., Gamper, N., Hilgemann, D. W. & Shapiro, M. S., Oct 26 2005, In: Journal of Neuroscience. 25, 43, p. 9825-9835 11 p.Research output: Contribution to journal › Article › peer-review
216 Scopus citations -
STIM is a Ca2+ sensor essential for Ca2+-store- depletion-triggered Ca2+ influx
Liou, J., Kim, M. L., Won, D. H., Jones, J. T., Myers, J. W., Ferrell, J. E. & Meyer, T., Jul 12 2005, In: Current Biology. 15, 13, p. 1235-1241 7 p.Research output: Contribution to journal › Article › peer-review
1820 Scopus citations -
2004
Lipid- and mechanosensitivities of sodium/hydrogen exchangers analyzed by electrical methods
Fuster, D., Moe, O. W. & Hilgemann, D. W., Jul 13 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 28, p. 10482-10487 6 p.Research output: Contribution to journal › Article › peer-review
Open Access71 Scopus citations -
Multiple transport modes of the cardiac Na+/Ca2+ exchanger
Kang, T. M. & Hilgemann, D. W., Feb 5 2004, In: Nature. 427, 6974, p. 544-548 5 p.Research output: Contribution to journal › Article › peer-review
128 Scopus citations -
2003
Ion fluxes in giant excised cardiac membrane patches detected and quantified with ion-selective microelectrodes
Kang, T. M., Markin, V. S. & Hilgemann, D. W., Apr 1 2003, In: Journal of General Physiology. 121, 4, p. 325-347 23 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
Protein kinase C inhibits ROMK1 channel activity via a phosphatidylinositol 4,5-bisphosphate-dependent mechanism
Zeng, W. Z., Li, X. J., Hilgemann, D. W. & Huang, C. L., May 9 2003, In: Journal of Biological Chemistry. 278, 19, p. 16852-16856 5 p.Research output: Contribution to journal › Article › peer-review
68 Scopus citations -
2002
Modulation of cardiac PIP2 by cardioactive hormones and other physiologically relevant interventions
Nasuhoglu, C., Feng, S., Mao, Y., Shammat, I., Yamamato, M., Earnest, S., Lemmon, M. & Hilgemann, D. W., 2002, In: American Journal of Physiology - Cell Physiology. 283, 1 52-1, p. C223-C234Research output: Contribution to journal › Article › peer-review
77 Scopus citations -
Nonradioactive analysis of phosphatidylinositides and other anionic phospholipids by anion-exchange high-performance liquid chromatography with suppressed conductivity detection
Nasuhoglu, C., Feng, S., Mao, J., Yamamoto, M., Yin, H. L., Earnest, S., Barylko, B., Albanesi, J. P. & Hilgemann, D. W., Feb 15 2002, In: Analytical biochemistry. 301, 2, p. 243-254 12 p.Research output: Contribution to journal › Article › peer-review
114 Scopus citations -
Sodium-calcium exchange stoichiometry: Is the noose tightening?
Kang, T. M., Steciuk, M. & Hilgemann, D. W., 2002, In: Annals of the New York Academy of Sciences. 976, p. 142-151 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Stoichiometry: A discussion
Philipson, K., Hilgemann, D., Bers, D., Lederer, J., Noble, D., Blaustein, M., Kimura, J. & DiPolo, R., 2002, In: Annals of the New York Academy of Sciences. 976, p. 152-153 2 p.Research output: Contribution to journal › Article › peer-review