Office of the Associate Dean - Southwestern Medical School - Administration

Research output

Research output per year 1973 1974 1975 1981 1982 1987 1988 1991 2018 2022

• 64 Article
• 2 Review article
• 1 Comment/debate

Research output per year

Research output per year

Search results

• 2022

  Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90

  Alzheimer's Disease Genetics Consortium, Dec 2022, In: Scientific reports. 12, 1, 6117.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Alzheimer Disease 100%
  • Single Nucleotide Polymorphism 48%
  • Genome-Wide Association Study 29%
  • Meta-Analysis 21%
  • Alleles 20%
  10 Scopus citations

• New insights into the genetic etiology of Alzheimer’s disease and related dementias

  EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC & CHARGE, Apr 1 2022, In: Nature genetics. 54, 4, p. 412-436 25 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dementia 100%
  • Alzheimer Disease 92%
  • Proxy 17%
  • Genome-Wide Association Study 17%
  • Microglia 17%
  549 Scopus citations
• 2020

  Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

  The Alzheimer’s Disease Genetics Consortium, Dec 1 2020, In: Nature communications. 11, 1, 667.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apolipoprotein 100%
  • Homozygote 89%
  • Alzheimer Disease 63%
  • Apolipoprotein E4 55%
  • genes 31%
  223 Scopus citations
• 2019

  Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

  Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Mar 1 2019, In: Nature genetics. 51, 3, p. 414-430 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Immunity 100%
  • Alzheimer Disease 95%
  • Meta-Analysis 91%
  • Lipids 80%
  • Serum Amyloid A Protein 35%
  1510 Scopus citations
• 2018

  Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

  ARUK Consortium, GERAD/PERADES, CHARGE, ADGC, EADI, International Genomics of Alzheimer's Project (IGAP), ARUK Consortium & GERAD/PERADES, CHARGE, ADGC, EADI, Jan 1 2018, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 595-598 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cholesterol Ester Transfer Proteins 100%
  • HDL Cholesterol 63%
  • Alzheimer Disease 55%
  • Genes 28%
  • Single Nucleotide Polymorphism 17%
  2 Scopus citations

• Sex-specific association of apolipoprotein e with cerebrospinal fluid levels of tau

  Alzheimer's Disease Genetics Consortium and the Alzheimer's Disease Neuroimaging Initiative, Aug 1 2018, In: JAMA neurology. 75, 8, p. 989-998 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apolipoproteins 100%
  • Apolipoproteins E 89%
  • Cerebrospinal Fluid 73%
  • Neurofibrillary Tangles 37%
  • Sex Characteristics 35%
  196 Scopus citations

• Sex-specific genetic predictors of Alzheimer’s disease biomarkers

  Alzheimer’S Disease Neuroimaging Initiative (Adni) & The Alzheimer Disease Genetics Consortium (Adgc), Dec 1 2018, In: Acta Neuropathologica. 136, 6, p. 857-872 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Alzheimer Disease 100%
  • Biomarkers 83%
  • Genome-Wide Association Study 67%
  • Amyloid 61%
  • Endophenotypes 57%
  69 Scopus citations
• 2017

  Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

  Sims, R., Van Der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R., & 429 othersHoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Jr, W. T. L., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J., Sotolongo-Grau, O., Katz, M. J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Fairén, M. D., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J. T., Lord, J., Turton, J., Hartmann, A. M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleó, A., Fortea, J., Blesa, R., Barber, I. S., Brookes, K., Cupidi, C., Maletta, R. G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N. C., Hardy, J., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barnes, L. L., Barral, S., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Diaz, C. C., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Decarli, C., Dick, M., Duara, R., Evans, D. A., Faber, K. M., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Galasko, D. R., Gearing, M., Geschwind, D. H., Gilbert, J. R., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Abner, E., Jin, L. W., Jun, G., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Laferla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lunetta, K. L., Lyketsos, C. G., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Paulson, H. L., Perry, W., Peskind, E., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C. E., Yu, L., Garzia, F., Golamaully, F., Septier, G., Engelborghs, S., Vandenberghe, R., De Deyn, P. P., Fernadez, C. M., Benito, Y. A., Thonberg, H., Forsell, C., Lilius, L., Kinhult-Stählbom, A., Kilander, L., Brundin, R., Concari, L., Helisalmi, S., Koivisto, A. M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J. J., Keene, C. D., Tschanz, J., Fitzpatrick, A. L., Kukull, W. A., Norton, M., Aspelund, T., Larson, E. B., Munger, R., Rotter, J. I., Lipton, R. B., Bullido, M. J., Hofman, A., Montine, T. J., Coto, E., Boerwinkle, E., Petersen, R. C., Alvarez, V., Rivadeneira, F., Reiman, E. M., Gallo, M., O'Donnell, C. J., Reisch, J. S., Bruni, A. C., Royall, D. R., Dichgans, M., Sano, M., Galimberti, D., St George-Hyslop, P., Scarpini, E., Tsuang, D. W., Mancuso, M., Bonuccelli, U., Winslow, A. R., Daniele, A., Wu, C. K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D. C., Bras, J., Guerreiro, R., Al-Chalabi, A., Shaw, C. E., Collinge, J., Mann, D., Tsolaki, M., Clarimón, J., Sussams, R., Lovestone, S., O'Donovan, M. C., Owen, M. J., Behrens, T. W., Mead, S., Goate, A. M., Uitterlinden, A. G., Holmes, C., Cruchaga, C., Ingelsson, M., Bennett, D. A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Holmans, P. A., Pericak-Vance, M. A., Amouyel, P., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., Sep 1 2017, In: Nature genetics. 49, 9, p. 1373-1384 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gene Frequency 100%
  • Innate Immunity 94%
  • Alzheimer Disease 79%
  • Microglia 34%
  • Odds Ratio 32%
  625 Scopus citations

• Transethnic genome-wide scan identifies novel Alzheimer's disease loci

  Alzheimer's Disease Genetics Consortium, Jul 1 2017, In: Alzheimer's and Dementia. 13, 7, p. 727-738 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • dementia 100%
  • Alzheimer Disease 77%
  • Genome 67%
  • Single Nucleotide Polymorphism 50%
  • Genome-Wide Association Study 41%
  123 Scopus citations
• 2016

  A novel Alzheimer disease locus located near the gene encoding tau protein

  Genetic and Environmental Risk in Alzheimer's Disease (GERAD) Consortium & IGAP Consortium, Jan 1 2016, In: Molecular psychiatry. 21, 1, p. 108-117 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • tau Proteins 100%
  • Single Nucleotide Polymorphism 66%
  • Alzheimer Disease 61%
  • Genes 32%
  • Exons 28%
  179 Scopus citations

• Assessment of the genetic variance of late-onset Alzheimer's disease

  Alzheimer's Disease Genetics Consortium (ADGC), May 1 2016, In: Neurobiology of Aging. 41, p. 200.e13-200.e20

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Alzheimer Disease 100%
  • Single Nucleotide Polymorphism 61%
  • Netrin Receptors 30%
  • Multifactorial Inheritance 22%
  • Amyloid beta-Protein Precursor 21%
  60 Scopus citations
• 2015

  Lipoprotein-associated phospholipase A2, homocysteine, and Alzheimer's disease

  Texas Alzheimer's Disease Research and Care Consortium, Dec 1 2015, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1, 4, p. 464-471 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 1-Alkyl-2-acetylglycerophosphocholine Esterase 100%
  • Homocysteine 70%
  • Alzheimer Disease 50%
  • 5'-palmitoyl cytarabine 15%
  • Cardiovascular Diseases 11%
  24 Scopus citations
• 2014

  Total cholesterol and neuropsychiatric symptoms in Alzheimer's disease: The impact of total cholesterol level and gender

  Hall, J. R., Wiechmann, A. R., Johnson, L. A., Edwards, M., Barber, R. C., Cunningham, R., Singh, M., O'Bryant, S. E., Doody, R., Roundtree, S., Pavlik, V., Chan, W., Massman, P., Darby, E., Evans, T., Williams, B., Schrimsher, G., Dentino, A., Orozco, R., Fairchild, T., & 16 othersKnebl, J., Mains, D., Alvarez, L., Adams, P., Rosenberg, R., Weiner, M., Quiceno, M., Reisch, J., Huebinger, R., Xiao, G., Svetlik, D., Werry, A., Smith, J., Royall, D., Palmer, R. & Polk, M., Nov 7 2014, In: Dementia and Geriatric Cognitive Disorders. 38, p. 300-309 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Alzheimer Disease 100%
  • Cholesterol 94%
  • Hypercholesterolemia 51%
  • Psychotic Disorders 48%
  • Apathy 33%
  10 Scopus citations
• 2012

  Lipids and adipokines as risk factors for Alzheimer's disease

  Warren, M. W., Hynan, L. S., Weiner, M. F., Doody, R., Rountree, S., Capriles, V., Ballantyne, C., Darby, E., Dawson, T., Hittle, A., Khaleeg, A., O'Bryant, S., Grammas, P., Williams, B., Wu, C. K., Zhang, Y., Schrimsher, G., Dentino, A., Momeni, P., Hill, L., & 16 othersFairchild, T., Knebl, J., Barber, R., Mains, D., Alvarez, L., Adams, P., Rosenberg, R., Reisch, J., Huebinger, R., Svetlik, D., Murray, J. S. M., Sears, T., Royall, D., Hazuda, H., Palmer, R. & Polk, M., 2012, In: Journal of Alzheimer's Disease. 29, 1, p. 151-157 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adipokines 100%
  • dementia 87%
  • Alzheimer Disease 67%
  • Lipids 57%
  • Adiponectin 47%
  73 Scopus citations
• 2011

  A blood-based algorithm for the detection of Alzheimer's disease

  O'Bryant, S. E., Xiao, G., Barber, R., Reisch, J., Hall, J., Cullum, C. M., Doody, R., Fairchild, T., Adams, P., Wilhelmsen, K. & Diaz-Arrastia, R., Sep 2011, In: Dementia and Geriatric Cognitive Disorders. 32, 1, p. 55-62 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Alzheimer Disease 100%
  • Blood Proteins 68%
  • Biomarkers 67%
  • Neuropsychological Tests 55%
  • Area Under Curve 41%
  82 Scopus citations
• 2010

  A serum protein-based algorithm for the detection of Alzheimer disease

  O'Bryant, S. E., Xiao, G., Barber, R., Reisch, J., Doody, R., Fairchild, T., Adams, P., Waring, S. & Diaz-Arrastia, R., Sep 2010, In: Archives of neurology. 67, 9, p. 1077-1081 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Protein 100%
  • Biomarkers 99%
  • Alzheimer's Disease 95%
  • Blood Proteins 73%
  • Alzheimer Disease 64%
  204 Scopus citations
• 1998

  The Effects of Thyroid Hormone Level and Action in Developing Brain: Are These Targets for the Actions of Polychlorinated Biphenyls and Dioxins?

  Sher, E. S., Xu, X. M., Adams, P. M., Craft, C. M. & Stein, S. A., Jan 1998, In: Toxicology and Industrial Health. 14, 2, p. 121-158 38 p.

  Research output: Contribution to journal › Article › peer-review

  • Thyroid Hormone 100%
  • Dioxins 98%
  • Polychlorinated Biphenyls 92%
  • Polychlorobiphenyl 86%
  • Thyroid Hormones 74%
  48 Scopus citations
• 1997

  Altered amyloid protein processing in platelets of patients with Alzheimer disease

  Rosenberg, R. N., Baskin, F., Fosmire, J. A., Risser, R., Adams, P., Svetlik, D., Honig, L. S., Cullum, C. M. & Weiner, M. F., 1997, In: Archives of neurology. 54, 2, p. 139-144 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Amyloidogenic Proteins 100%
  • Protein 89%
  • Alzheimer's Disease 85%
  • Blood Platelets 58%
  • Alzheimer Disease 57%
  112 Scopus citations
• 1996

  Biology of the congenitally hypothyroid hyt/ hyt mouse

  Biesiada, E., Adams, P. M., Shanklin, D. R., Bloom, G. S. & Stein, S. A., 1996, In: Advances in Neuroimmunology. 6, 4, p. 309-346 38 p.

  Research output: Contribution to journal › Article › peer-review

  • Hypothyroidism 100%
  • Tubulin 70%
  • Brain 64%
  • Microtubules 63%
  • Protein Isoforms 52%
  36 Scopus citations

• Genetic factors for the development of Alzheimer disease in the Cherokee Indian

  Rosenberg, R. N., Richter, R. W., Risser, R. C., Taubman, K., Prado-Farmer, I., Ebalo, E., Posey, J., Kingfisher, D., Dean, D., Weiner, M. F., Svetlik, D., Adams, P., Honig, L. S., Cullum, C. M., Schaefer, F. V. & Schellenberg, G. D., Oct 1996, In: Archives of neurology. 53, 10, p. 997-1000 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Cherokee 100%
  • Alzheimer's Disease 82%
  • Alzheimer Disease 55%
  • Ancestry 38%
  • Allele 37%
  50 Scopus citations
• 1993

  The effects of congenital hypothyroidism using the hyt/hyt mouse on locomotor activity and learned behavior

  Anthony, A., Adams, P. M. & Stein, S. A., Sep 1993, In: Hormones and Behavior. 27, 3, p. 418-433 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Congenital Hypothyroidism 100%
  • Locomotion 72%
  • Spatial Learning 30%
  • Maze Learning 29%
  • Swimming 26%
  37 Scopus citations
• 1991

  Hypothyroidism reduces the rate of slow component a (SCa) axonal transport and the amount of transported tubulin in the hyt/hyt mouse optic nerve

  Stein, S. A., Kirkpatrick, L. L., Shanklin, D. R., Adams, P. M. & Brady, S. T., Jan 1991, In: Journal of Neuroscience Research. 28, 1, p. 121-133 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Axonal Transport 100%
  • Tubulin 86%
  • Optic Nerve 82%
  • Hypothyroidism 81%
  • Brain 39%
  24 Scopus citations

• Hypothyroidism selectively reduces the rate and amount of transport for specific SCb proteins in the hyt/hyt mouse optic nerve

  Stein, S. A., McIntire, D. D., Kirkpatrick, L. L., Adams, P. M. & Brady ., T., Sep 1991, In: Journal of Neuroscience Research. 30, 1, p. 28-41 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Optic Nerve 100%
  • Hypothyroidism 98%
  • Axonal Transport 51%
  • Clathrin 51%
  • Calmodulin 45%
  18 Scopus citations

• The site of the molecular defect in the thyroid gland of the hyt/hyt mouse: abnormalities in the TSH receptor-G protein complex.

  Stein, S. A., Zakarija, M., McKenzie, J. M., Shanklin, D. R., Palnitkar, M. B. & Adams, P. M., 1991, In: Thyroid : official journal of the American Thyroid Association. 1, 3, p. 257-266 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Thyrotropin Receptors 100%
  • GTP-Binding Proteins 75%
  • Thyroid Gland 62%
  • Iodide Peroxidase 32%
  • Thyroglobulin 29%
  21 Scopus citations
• 1990

  Male-meadiated behavioral abnormalities

  Lowery, M. C., Au, W. W., Adams, P. M., Whorton, E. B. & Legator, M. S., Apr 1990, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 229, 2, p. 213-229 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Ionizing Radiation 100%
  • Paternal Exposure 66%
  • Drug 43%
  • Radiation 30%
  • Pharmaceutical Preparations 17%
  12 Scopus citations
• 1989

  Evaluation and characterization of the hypothyroid hyt/hyt Mouse i: Somatic and behavioral studies

  Adams, P. M., Stein, S. A., Palnitkar, M., Anthony, A., Gerrity, L. & Shanklin, D. R., 1989, In: Neuroendocrinology. 49, 2, p. 138-143 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Congenital Hypothyroidism 100%
  • Recessive Genes 53%
  • Psychological Adaptation 43%
  • Thyroxine 38%
  • Hypothyroidism 38%
  40 Scopus citations

• Evaluation and characterization of the hyt/hyt hypothyroid mouse: II. Abnormalities of TSH and the thyroid gland

  Stein, S. A., Shanklin, D. R., Krulich, L., Roth, M. G., Chubb, C. M. & Adams, P. M., 1989, In: Neuroendocrinology. 49, 5, p. 509-519 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Thyroid Gland 100%
  • Hypothyroidism 52%
  • Congenital Hypothyroidism 46%
  • Thyroglobulin 41%
  • Colloids 39%
  54 Scopus citations
• 1988

  Effects of maternal exposure to polychlorobiphenyls (pcbs) on f1 generation behavior in the rat

  Pantaleoni, G., Fanini, D., Sponta, A. M., Palumbo, G., Giorgi, R. & Adams, P. M., Dec 1 1988, In: Toxicological Sciences. 11, 1, p. 440-449 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Maternal Exposure 100%
  • Polychlorobiphenyl 92%
  • Lactation 42%
  • Pregnancy 23%
  • Teratogenesis 19%
  115 Scopus citations

• Effects of maternal exposure to polychlorobiphenyls (pcbs) on f1 generation behavior in the rat

  Pantaleoni, G., Fanini, D., Sponta, A. M., Palumbo, G., Giorgi, R. & Adams, P. M., 1988, In: Toxicological Sciences. 11, 1, p. 440-449 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Maternal Exposure 100%
  • Polychlorobiphenyl 92%
  • Lactation 42%
  • Pregnancy 23%
  • Teratogenesis 19%

• Toxic exposure to ethylene dibromide and mercuric chloride: Effects on laboratory-reared octopuses

  Adams, P. M., Hanlon, R. T. & Forsythe, J. W., 1988, In: Neurotoxicology and Teratology. 10, 6, p. 519-523 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ethylene Dibromide 100%
  • Octopodiformes 83%
  • Mercuric Chloride 77%
  • Toxic 42%
  • Poisons 42%
  8 Scopus citations
• 1987

  Cyclophosphamide: Effects of paternal exposure on the brain chemistry of the f₁ progeny

  Hsu, L. L., Adams, P. M. & Legator, M. S., Aug 1987, In: Journal of Toxicology and Environmental Health. 21, 4, p. 471-481 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Brain Chemistry 100%
  • Paternal Exposure 95%
  • Cyclophosphamide 83%
  • Rats 69%
  • Glutamic Acid 62%
  10 Scopus citations

• Perinatal diazepam exposure: Behavioral and neurochemical consequences

  Lauer, J. A., Adams, P. M. & Johnson, K. M., 1987, In: Neurotoxicology and Teratology. 9, 3, p. 213-219 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Diazepam 100%
  • Psychological Extinction 27%
  • Benzodiazepine 27%
  • Benzodiazepines 24%
  • Avoidance Learning 19%
  17 Scopus citations
• 1985

  Effect of acute acrylonitrile exposure on metrazol induced seizures in the rat

  Fanini, D., Trieff, N. M., Sadagopa Ramanujam, V. M., Ahmed, A. E. & Adams, P. M., 1985, In: NeuroToxicology. 6, 1, p. 29-34 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Acrylonitrile 100%
  • Pentylenetetrazole 81%
  • Seizures 49%
  • Cyanides 20%
  • Lethal 19%
  5 Scopus citations

• Ethylene dibromide: effects of paternal exposure on the neurotransmitter enzymes in the developing brain of F₁ progeny

  Hsu, L. L., Adams, P. M., Fanini, D. & Legator, M. S., Aug 1985, In: Mutation Research/Environmental Mutagenesis and Related Subjects. 147, 4, p. 197-203 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Ethylene Dibromide 100%
  • Paternal Exposure 92%
  • Neurotransmitter 63%
  • Neurotransmitter Agents 49%
  • Enzymes 31%
  11 Scopus citations
• 1984

  Effects of paternal ethylene dibromide exposure on F₁ generation behavior in the rat

  Fanini, D., Legator, M. S. & Adams, P. M., Mar 1984, In: Mutation Research Letters. 139, 3, p. 133-138 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Ethylene Dibromide 100%
  • Motor Activity 15%
  • Reflex 12%
  • Therapeutics 2%
  18 Scopus citations

• Male‐Transmitted developmental and neurobehavioral deficits

  Adams, P. M., Shabrawy, O. & Legator, M. S., 1984, In: Teratogenesis, Carcinogenesis, and Mutagenesis. 4, 1, p. 149-169 21 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations
• 1983

  Post-meiotic cell mediation of behavior in progeny of male rats treated with cyclophosphamide

  Fabricant, J. D., Legator, M. S. & Adams, P. M., Feb 1983, In: Mutation Research Letters. 119, 2, p. 185-190 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclophosphamide 100%
  • Fertilization 77%
  • Paternal Exposure 57%
  • Inbred F344 Rats 40%
  • Germ Cells 35%
  25 Scopus citations
• 1982

  Active avoidance behavior in the F₁ progeny of male rats exposed to cyclophosphamide prior to fertilization

  Adams, P. M., Fabricant, J. D. & Legator, M. S., Dec 1 1982, In: Neurobehavioral Toxicology and Teratology. 4, 5, p. 531-534 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclophosphamide 100%
  • Avoidance Learning 88%
  • Fertilization 76%
  • Breeding 47%
  • Psychological Extinction 35%
  18 Scopus citations

• Effects of naloxone, metenkephalin, and morphine on phencyclidine-induced behavior in the rat

  Castellani, S., Giannini, A. J. & Adams, P. M., Mar 1982, In: Psychopharmacology. 78, 1, p. 76-80 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Phencyclidine 100%
  • Naloxone 79%
  • Morphine 70%
  • Ataxia 59%
  • Stereotyped Behavior 25%
  27 Scopus citations

• Effects of perinatal chlordiazepoxide exposure on rat preweaning and postweaning behavior

  Adams, P. M., Dec 1 1982, In: Neurobehavioral Toxicology and Teratology. 4, 3, p. 279-282 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Chlordiazepoxide 100%
  • Swimming 17%
  • Teratogens 11%
  • Avoidance Learning 10%
  • Psychological Extinction 9%
  22 Scopus citations

• Phencyclidine intoxication: Assessment of possible antidotes

  Castellani, S., Giannini, A. J., Alexander Boeringa, J. & Adams, P. M., Jan 1 1982, In: Clinical Toxicology. 19, 3, p. 313-319 7 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Physostigmine and haloperidol treatment of acute phencyclidine intoxication

  Castellani, S., Giannini, A. J. & Adams, P. M., Jan 1 1982, In: American Journal of Psychiatry. 139, 4, p. 508-510 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Phencyclidine 100%
  • Physostigmine 97%
  • Haloperidol 81%
  • Delusions 45%
  • Hallucinations 42%
  27 Scopus citations

• Physostigmine treatment of acute phenycyclidine intoxication

  Castellani, S., Adams, P. M. & Giannini, A. J., Jan 1 1982, In: Journal of Clinical Psychiatry. 43, 1, p. 10-11 2 p.

  Research output: Contribution to journal › Article › peer-review

  • Physostigmine 100%
  • Phencyclidine 68%
  • Brief Psychiatric Rating Scale 35%
  • Routine Diagnostic Tests 24%
  • Clinical Studies 17%
  12 Scopus citations
• 1981

  Active avoidance behavior in the F₁ progeny of male rats exposed to cyclophosphamide prior to fertilization

  Adams, P. M., Fabricant, J. D. & Legator, M. S., 1981, In: Teratology. 24, 1, p. 52A

  Research output: Contribution to journal › Article › peer-review

• Acute and chronic phencyclidine effects on locomotor activity, stereotypy and ataxia in rats

  Castellani, S. & Adams, P. M., Jul 17 1981, In: European Journal of Pharmacology. 73, 2-3, p. 143-154 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Tabes Dorsalis 100%
  • Phencyclidine 77%
  • Ataxia 60%
  • Locomotion 55%
  • Apomorphine 45%
  138 Scopus citations

• Cyclophosphamide-induced spermatogenic effects detected in the F ₁ generation by behavioral testing

  Adams, P. M., Fabricant, J. D. & Legator, M. S., Jan 1 1981, In: Science. 211, 4477, p. 80-82 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclophosphamide 100%
  • Body Weight 25%
  55 Scopus citations

• Effects of dopaminergic drugs on phencyclidine-induced behavior in the rat

  Castellani, S. & Adams, P. M., Apr 1981, In: Neuropharmacology. 20, 4, p. 371-374 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Phencyclidine 100%
  • Dopamine Agents 94%
  • Apomorphine 29%
  • Locomotion 24%
  • Dopamine 21%
  49 Scopus citations

• Potentiation of apomorphine and d-amphetamine effects by naloxone

  Adams, P. M., Beauchamp, R. & Alston, C., Feb 9 1981, In: Life Sciences. 28, 6, p. 629-634 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Apomorphine 100%
  • Naloxone 92%
  • Dextroamphetamine 85%
  • Locomotion 32%
  • Narcotic Antagonist 16%
  34 Scopus citations

• The scientist's concern for animal welfare.

  Adams, P. M., Apr 1981, In: Psychopharmacology bulletin. 17, 2, p. 91-93 3 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations
• 1980

  Interaction of phencyclidine with drugs affecting cholinergic neurotransmission

  Adams, P. M., Feb 1980, In: Neuropharmacology. 19, 2, p. 151-153 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Phencyclidine 100%
  • Synaptic Transmission 70%
  • Cholinergic Agents 69%
  • methylatropine 59%
  • Physostigmine 48%
  27 Scopus citations