IC-Core Microbiome

Research output

Research output per year 1954 1990 1991 1994 1995 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2024

• 2654 Article
• 292 Review article
• 86 Comment/debate
• 35 Short survey
• 109 More
  • 29 Chapter
  • 28 Letter
  • 26 Editorial
  • 22 Conference contribution
  • 2 Book
  • 2 Foreword/postscript

Research output per year

Research output per year

Search results

• 2024

  Association between SARS-CoV-2 infection and select symptoms and conditions 31 to 150 days after testing among children and adults

  Zhang, Y., Romieu-Hernandez, A., Boehmer, T. K., Azziz-Baumgartner, E., Carton, T. W., Gundlapalli, A. V., Fearrington, J., Nagavedu, K., Dea, K., Moyneur, E., Cowell, L. G., Kaushal, R., Mayer, K. H., Puro, J., Rasmussen, S. A., Thacker, D., Weiner, M. G., Saydah, S. & Block, J. P., Dec 2024, In: BMC Infectious Diseases. 24, 1, 181.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Infections 32%
  • Child 29%
  • Odds Ratio 17%
  • Electronic Health Records 13%

• CDKL5 regulates p62-mediated selective autophagy and confers protection against neurotropic viruses

  Thinwa, J. W., Zou, Z., Parks, E., Sebti, S., Hui, K., Wei, Y., Goodarzi, M., Singh, V., Urquhart, G., Jewell, J. L., Pfeiffer, J. K., Levine, B., Reese, T. A. & Shiloh, M. U., Jan 20 2024, In: Journal of Clinical Investigation. 134, 1, e168544.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cyclins 100%
  • Autophagy 79%
  • Sindbis Virus 59%
  • Viruses 55%
  • Capsid 47%

• Coordinating virus research: The Virus Infectious Disease Ontology

  Beverley, J., Babcock, S., Carvalho, G., Cowell, L. G., Duesing, S., He, Y., Hurley, R., Merrell, E., Scheuermann, R. H. & Smith, B., Jan 2024, In: PloS one. 19, 1 January, e0285093.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Communicable Diseases 100%
  • Virus Diseases 85%
  • Biological Ontologies 80%
  • Viruses 77%
  • SARS Virus 34%

• Dynamic molecular architecture and substrate recruitment of cullin3–RING E3 ligase CRL3^KBTBD2

  Hu, Y., Zhang, Z., Mao, Q., Zhang, X., Hao, A., Xun, Y., Wang, Y., Han, L., Zhan, W., Liu, Q., Yin, Y., Peng, C., Moresco, E. M. Y., Chen, Z., Beutler, B. & Sun, L., Feb 2024, In: Nature Structural and Molecular Biology. 31, 2, p. 336-350 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Ubiquitin-Protein Ligases 100%
  • Molecular Dynamics Simulation 97%
  • Ubiquitination 94%
  • COP9 Signalosome Complex 73%
  • Dwarfism 60%

• E3 ubiquitin ligase Herc3 deficiency leads to accumulation of subretinal microglia and retinal neurodegeneration

  Zegeye, Y., Aredo, B., Yuksel, S., Kirman, D. C., Kumar, A., Chen, B., Turpin, E., Shresta, S., He, Y. G., Gautron, L., Tang, M., Li, X., DiCesare, S. M., Hulleman, J. D., Xing, C., Ludwig, S., Moresco, E. M. Y., Beutler, B. A. & Ufret-Vincenty, R. L., Dec 2024, In: Scientific reports. 14, 1

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ubiquitin-Protein Ligases 100%
  • Microglia 89%
  • Retina 50%
  • Retinal Diseases 36%
  • Retinal Degeneration 35%

• FEAR antiviral response pathway is independent of interferons and countered by poxvirus proteins

  Rex, E. A., Seo, D., Chappidi, S., Pinkham, C., Brito Oliveira, S., Embry, A., Heisler, D., Liu, Y., Munir, M., Luger, K., Alto, N. M., da Fonseca, F. G., Orchard, R., Hancks, D. C. & Gammon, D. B., 2024, (Accepted/In press) In: Nature microbiology.

  Research output: Contribution to journal › Article › peer-review

  • Poxviridae 100%
  • Interferons 66%
  • Chromatin 63%
  • Antiviral Agents 61%
  • Proteins 26%
  1 Scopus citations

• FOXP1 and KLF2 reciprocally regulate checkpoints of stem-like to effector transition in CAR T cells

  Zhu, Z., Lou, G., Teng, X. L., Wang, H., Luo, Y., Shi, W., Yihunie, K., Hao, S., DeGolier, K., Liao, C., Huang, H., Zhang, Q., Fry, T., Wang, T., Yao, C. & Wu, T., Jan 2024, In: Nature immunology. 25, 1, p. 117-128 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 45%
  • CD8 Antigens 22%
  • Transcription Factors 18%
  • Gene Regulatory Networks 17%
  1 Scopus citations

• Genetic determinants of blood pressure and heart rate identified through ENU-induced mutagenesis with automated meiotic mapping

  Teixeira, S. K., Pontes, R., Zuleta, L. F. G., Wang, J., Xu, D., Hildebrand, S., Russell, J. L., Zhan, X., Choi, M., Tang, M., Li, X., Ludwig, S., Beutler, B. & Krieger, J. E., Mar 2024, In: Science Advances. 10, 9, eadj9797.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mutagenesis 100%
  • Heart Rate 74%
  • Blood Pressure 64%
  • Genes 35%
  • Reverse Genetics 16%

• Genetic influences on motor learning and performance and superperforming mutants revealed by random mutational survey of the mouse genome

  Jakkamsetti, V., Ma, Q., Angulo, G., Scudder, W., Beutler, B. & Pascual, J. M., 2024, (Accepted/In press) In: Journal of Physiology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Learning 100%
  • Genome 92%
  • Mutation 76%
  • Genes 32%
  • Histone Methyltransferases 18%

• Genome-wide CRISPR activation screen identifies JADE3 as an antiviral activator of NF-kB–dependent IFITM3 expression

  Munir, M., Embry, A., Doench, J. G., Heaton, N. S., Wilen, C. B. & Orchard, R. C., Apr 2024, In: Journal of Biological Chemistry. 300, 4, 107153.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Clustered Regularly Interspaced Short Palindromic Repeats 100%
  • Influenza A virus 95%
  • Interferons 80%
  • Antiviral Agents 74%
  • Genome 59%

• Noninferiority of Hypofractionated vs Conventional Postprostatectomy Radiotherapy for Genitourinary and Gastrointestinal Symptoms: The NRG-GU003 Phase 3 Randomized Clinical Trial

  Buyyounouski, M. K., Pugh, S. L., Chen, R. C., Mann, M. J., Kudchadker, R. J., Konski, A. A., Mian, O. Y., Michalski, J. M., Vigneault, E., Valicenti, R. K., Barkati, M., Lawton, C. A. F., Potters, L., Monitto, D. C., Kittel, J. A., Schroeder, T. M., Hannan, R., Duncan, C. E., Rodgers, J. P., Feng, F., & 1 othersSandler, H. M., 2024, (Accepted/In press) In: JAMA Oncology.

  Research output: Contribution to journal › Article › peer-review

  • Phase III Clinical Trials 100%
  • Radiotherapy 57%
  • Randomized Controlled Trials 56%
  • Prostatic Neoplasms 8%
  • Poisons 8%
  2 Scopus citations

• Stereotactic ablative radiotherapy for primary renal cell carcinoma

  Yang, D. X., Kwon, Y. S., Timmerman, R. & Hannan, R., Jan 2024, In: Clinical and Translational Radiation Oncology. 44, 100705.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Renal Cell Carcinoma 100%
  • Radiotherapy 71%
  • Radio 17%
  • Registries 13%
  • Neoplasms 11%

• STING licensing of type I dendritic cells potentiates antitumor immunity

  Wang, J., Li, S., Wang, M., Wang, X., Chen, S., Sun, Z., Ren, X., Huang, G., Sumer, B. D., Yan, N., Fu, Y. X. & Gao, J., Feb 2024, In: Science Immunology. 9, 92, eadj3945.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Licensure 100%
  • Interferons 84%
  • Dendritic Cells 82%
  • Immunity 75%
  • Genes 37%

• Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance

  Rodrigues, M., Sabaeifard, P., Yildiz, M. S., Lyon, A., Coughlin, L., Ahmed, S., Poulides, N., Toprak, A. C., Behrendt, C., Wang, X., Monogue, M., Kim, J., Gan, S., Zhan, X., Filkins, L., Williams, N. S., Hooper, L. V., Koh, A. Y. & Toprak, E., Mar 13 2024, In: Cell Host and Microbe. 32, 3, p. 396-410.e6

  Research output: Contribution to journal › Article › peer-review

  • Cefepime 100%
  • gastrointestinal system 71%
  • Gastrointestinal Tract 64%
  • antibiotics 55%
  • Bacteria 50%
  1 Scopus citations

• The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

  Cruz, V. E., Weirich, C. S., Peddada, N. & Erzberger, J. P., Dec 2024, In: Nature communications. 15, 1, 3296.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Large Ribosome Subunits 100%
  • biological evolution 96%
  • Peptidyl Transferases 92%
  • ribosomes 90%
  • Ribosomes 65%

• Viable mutations of mouse midnolin suppress B cell malignancies

  Zhong, X., Peddada, N., Moresco, J. J., Wang, J., Jiang, Y., Rios, J. J., Moresco, E. M. Y., Choi, J. H. & Beutler, B., Jun 3 2024, In: The Journal of experimental medicine. 221, 6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • midnolin 100%
  • B-Lymphocytes 32%
  • Mutation 23%
  • Proteasome Endopeptidase Complex 22%
  • Lymphopoiesis 15%

• Wnt16 Promotes Vascular Smooth Muscle Contractile Phenotype and Function via Taz (Wwtr1) Activation in Male LDLR−/− Mice

  Behrmann, A., Zhong, D., Li, L., Xie, S., Mead, M., Sabaeifard, P., Goodarzi, M., Lemoff, A., Kozlitina, J. & Towler, D. A., Feb 1 2024, In: Endocrinology. 165, 2, bqad192.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Vascular Smooth Muscle 100%
  • Phenotype 61%
  • Cardiovascular Physiological Phenomena 43%
  • Bone and Bones 34%
  • Thoracic Aorta 28%
• 2023

  An epithelial cell-derived metabolite tunes immunoglobulin A secretion by gut-resident plasma cells

  Ceglia, S., Berthelette, A., Howley, K., Li, Y., Mortzfeld, B., Bhattarai, S. K., Yiew, N. K. H., Xu, Y., Brink, R., Cyster, J. G., Hooper, L. V., Randolph, G. J., Bucci, V. & Reboldi, A., Mar 2023, In: Nature immunology. 24, 3, p. 531-544 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Plasma Cells 100%
  • Immunoglobulin A 93%
  • Epithelial Cells 71%
  • Oxysterols 57%
  • Dietary Cholesterol 56%
  16 Scopus citations

• Anti–Neutrophil Extracellular Trap Antibodies in Antiphospholipid Antibody–Positive Patients: Results From the Antiphospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking Clinical Database and Repository

  the Antiphospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking, Aug 2023, In: Arthritis and Rheumatology. 75, 8, p. 1407-1414 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extracellular Traps 100%
  • Antiphospholipid Antibodies 88%
  • Antiphospholipid Syndrome 85%
  • Clinical Trials 46%
  • Databases 42%
  17 Scopus citations

• Atypical Adult-onset Still's disease with flagellate morphology in a patient with skin of color

  Vora, P., Kunzler, E., Dominguez, A. R., Vandergriff, T. & Harris-Tryon, T., Jul 2023, In: JAAD Case Reports. 37, p. 54-57 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Characterizing inflammatory profiles of suicidal behavior in adolescents: Rationale and design

  Chin Fatt, C., Ayvaci, E. R., Jha, M. K., Emslie, G., Gibson, S., Minhajuddin, A. T., Mayes, T. L., Farrar, J. D. & Trivedi, M. H., Mar 15 2023, In: Journal of affective disorders. 325, p. 55-61 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adolescent Behavior 100%
  • suicide 73%
  • Suicide 72%
  • adolescent 45%
  • blood samples 22%

• Comprehensive phenotypic analysis of diverse FOXN1 variants

  Moses, A., Bhalla, P., Thompson, A., Lai, L., Coskun, F. S., Seroogy, C. M., de la Morena, M. T., Wysocki, C. A. & van Oers, N. S. C., Nov 2023, In: Journal of Allergy and Clinical Immunology. 152, 5, p. 1273-1291.e15

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Thymus Gland 100%
  • T-Lymphocytes 51%
  • Organ Culture Techniques 48%
  • Mutation 46%
  • Forkhead Transcription Factors 27%
  2 Scopus citations

• Demographics and baseline disease characteristics of Black and Hispanic patients with multiple sclerosis in the open-label, single-arm, multicenter, phase IV CHIMES trial

  CHIMES investigators, Aug 2023, In: Multiple Sclerosis and Related Disorders. 76, 104794.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hispanic Americans 100%
  • Multiple Sclerosis 91%
  • Demography 67%
  • African Americans 26%
  • ocrelizumab 16%

• Dynamic kernel matching for non-conforming data: A case study of T cell receptor datasets

  Ostmeyer, J., Cowell, L. & Christley, S., Mar 2023, In: PloS one. 18, 3 March, e0265313.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • T-Cell Antigen Receptor 100%
  • Datasets 77%
  • Cytomegalovirus 24%
  • Antigens 15%

• Essential requirement for IER3IP1 in B cell development

  Zhong, X., Moresco, J. J., Keller, K., Lazaro, D. R., Ely, C., Moresco, E. M. Y., Beutler, B. & Choi, J., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 46, e2312810120.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • B-Lymphocyte Subsets 100%
  • Proteins 29%
  • X-Box Binding Protein 1 20%
  • B-Lymphocytes 20%
  • Ethylnitrosourea 18%

• Essential role of MFSD1-GLMP-GIMAP5 in lymphocyte survival and liver homeostasis

  Zhong, X., Moresco, J. J., Diedrich, J. K., Pinto, A. M., SoRelle, J. A., Wang, J., Keller, K., Ludwig, S., Moresco, E. M. Y., Beutler, B. & Choi, J. H., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 50, e2314429120.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lysosome-Associated Membrane Glycoproteins 100%
  • GTP Phosphohydrolases 77%
  • Immunity 55%
  • Homeostasis 49%
  • Lymphocytes 46%

• Factors Associated With Receipt of Molecular Testing and its Impact on Time to Initial Systemic Therapy in Metastatic Non-Small Cell Lung Cancer

  Osazuwa-Peters, O. L., Wilson, L. E., Check, D. K., Roberts, M. C., Srinivasan, S., Clark, A. G., Crawford, J., Chrischilles, E., Carnahan, R. M., Campbell, W. S., Cowell, L. G., Greenlee, R., Abbott, A. M., Mosa, A. S. M., Mandhadi, V., Stoddard, A. & Dinan, M. A., Jun 2023, In: Clinical lung cancer. 24, 4, p. 305-312 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Non-Small Cell Lung Carcinoma 100%
  • Comorbidity 29%
  • Therapeutics 18%
  • Proportional Hazards Models 11%
  • Datasets 9%
  1 Scopus citations

• Forward genetic screening using fundus spot scale identifies an essential role for Lipe in murine retinal homeostasis

  Yuksel, S., Aredo, B., Zegeye, Y., Zhao, C. X., Tang, M., Li, X., Hulleman, J. D., Gautron, L., Ludwig, S., Moresco, E. M. Y., Butovich, I. A., Beutler, B. A. & Ufret-Vincenty, R. L., Dec 2023, In: Communications Biology. 6, 1, 533.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • genetic testing 100%
  • Retinal 84%
  • neuroglia 80%
  • Genetic Testing 75%
  • Microglia 74%

• Gut microbiota depletion minimally affects the daily voluntary wheel running activity and food anticipatory activity in female and male C57BL/6J mice

  Ehichioya, D. E., Taufique, S. K. T., Magaña, I., Farah, S., Obata, Y. & Yamazaki, S., 2023, In: Frontiers in Physiology. 14, 1299474.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Running 100%
  • Gastrointestinal Microbiome 94%
  • Inbred C57BL Mouse 90%
  • Food 67%
  • Circadian Rhythm 50%

• Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity

  Choi, Y., Lichterman, J. N., Coughlin, L. A., Poulides, N., Li, W., Del Valle, P., Palmer, S. N., Gan, S., Kim, J., Zhan, X., Gao, Y., Evers, B. M., Hooper, L. V., Pasare, C. & Koh, A. Y., Mar 2023, In: Science Immunology. 8, 81, eabo2003.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gastrointestinal Microbiome 100%
  • Immunity 82%
  • Lymph Nodes 57%
  • Bacteria 41%
  • Dendritic Cells 36%
  15 Scopus citations

• Macrophages regulate gastrointestinal motility through complement component 1q

  Pendse, M., De Selle, H., Vo, N., Quinn, G., Dende, C., Li, Y., Salinas, C. N., Srinivasan, T., Propheter, D. C., Crofts, A. A., Koo, E., Hassell, B., Ruhn, K. A., Raj, P., Obata, Y. & Hooper, L. V., Apr 2023, In: eLife. 12, e78558.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Complement C1q 100%
  • Enteric Coating 89%
  • Gastrointestinal Motility 80%
  • Macrophages 46%
  • Neurogenic 37%
  3 Scopus citations

• Meropenem-vaborbactam restoration of first-line drug efficacy and comparison of meropenem-vaborbactam-moxifloxacin versus BPaL MDR-TB regimen

  Singh, S., Gumbo, T., Alffenaar, J. W., Boorgula, G. D., Shankar, P., Thomas, T. A., Dheda, K., Malinga, L., Raj, P., Aryal, S. & Srivastava, S., Dec 2023, In: International Journal of Antimicrobial Agents. 62, 6, 106968.

  Research output: Contribution to journal › Article › peer-review

  • meropenem and vaborbactam 100%
  • bedaquiline 85%
  • Moxifloxacin 68%
  • Linezolid 66%
  • Multidrug-Resistant Tuberculosis 63%

• Mesenchymal cell replacement corrects thymic hypoplasia in murine models of 22q11.2 deletion syndrome

  Bhalla, P., Du, Q., Kumar, A., Xing, C., Moses, A., Dozmorov, I., Wysocki, C. A., Cleaver, O. B., Pirolli, T. J., Markert, M. L., de la Morena, M. T., Baldini, A. & van Oers, N. S., Jul 3 2023, In: The Journal of clinical investigation. 133, 13

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Neuronal binding by antibodies can be influenced by low pH stress during the isolation procedure

  Zhang, W., Joshi, C., Smith, C., Ujas, T. A., Rivas, J. R., Cowell, L., Christley, S., Stowe, A. M. & Monson, N. L., Oct 2023, In: Journal of Immunological Methods. 521, 113535.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Antibodies 100%
  • Buffers 33%
  • Multiple Sclerosis 31%
  • Antigens 22%
  • Neurons 22%

• Neuron-binding antibody responses are associated with Black ethnicity in multiple sclerosis during natalizumab treatment

  Telesford, K. M., Smith, C., Mettlen, M., Davis, M. B., Cowell, L., Kittles, R., Vartanian, T. & Monson, N., 2023, In: Brain Communications. 5, 4, fcad218.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Natalizumab 100%
  • African Continental Ancestry Group 68%
  • Antibody Formation 62%
  • Multiple Sclerosis 61%
  • Neurons 42%

• Norovirus MLKL-like protein initiates cell death to induce viral egress

  Wang, G., Zhang, D., Orchard, R. C., Hancks, D. C. & Reese, T. A., Apr 6 2023, In: Nature. 616, 7955, p. 152-158 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Norovirus 100%
  • Phosphotransferases 59%
  • Cell Death 58%
  • Mitochondrial Membranes 34%
  • Viruses 30%
  10 Scopus citations

• OVOL2 sustains postnatal thymic epithelial cell identity

  Zhong, X., Peddada, N., Wang, J., Moresco, J. J., Zhan, X., Shelton, J. M., SoRelle, J. A., Keller, K., Lazaro, D. R., Moresco, E. M. Y., Choi, J. H. & Beutler, B., Dec 2023, In: Nature communications. 14, 1, 7786.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lymphopenia 100%
  • Demethylation 60%
  • maintenance 53%
  • Epithelial Cells 36%
  • disrupting 36%

• Phase 2 Trial of Stereotactic Ablative Radiotherapy for Patients with Primary Renal Cancer

  Hannan, R., McLaughlin, M. F., Pop, L. M., Pedrosa, I., Kapur, P., Garant, A., Ahn, C., Christie, A., Zhu, J., Wang, T., Robles, L., Durakoglugil, D., Woldu, S., Margulis, V., Gahan, J., Brugarolas, J., Timmerman, R. & Cadeddu, J., Sep 2023, In: European urology. 84, 3, p. 275-286 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Kidney Neoplasms 100%
  • Radiosurgery 98%
  • Radiotherapy 61%
  • Renal Cell Carcinoma 56%
  • Response Evaluation Criteria in Solid Tumors 56%
  14 Scopus citations

• Preliminary Evaluation of PTV Margins for Online Adaptive Radiation Therapy of the Prostatic Fossa

  Morgan, H. E., Wang, K., Yan, Y., Desai, N., Hannan, R., Chambers, E., Cai, B., Lin, M. H., Sher, D. J., Wang, J., Wang, A. Z., Jiang, S., Timmerman, R., Park, C. J. & Garant, A., Jul 1 2023, In: Practical Radiation Oncology. 13, 4, p. e345-e353

  Research output: Contribution to journal › Article › peer-review

  • Radiotherapy 100%
  • Cone-Beam Computed Tomography 96%
  • Patient Positioning 37%
  • Rectum 28%
  • Prostate 24%
  5 Scopus citations

• Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development

  Wang, X., He, Q., Zhou, C., Xu, Y., Liu, D., Fujiwara, N., Kubota, N., Click, A., Henderson, P., Vancil, J., Marquez, C. A., Gunasekaran, G., Schwartz, M. E., Tabrizian, P., Sarpel, U., Fiel, M. I., Diao, Y., Sun, B., Hoshida, Y., Liang, S., & 1 othersZhong, Z., Jan 10 2023, In: Immunity. 56, 1, p. 58-77.e11

  Research output: Contribution to journal › Article › peer-review

  • Overnutrition 100%
  • Licensure 73%
  • Non-alcoholic Fatty Liver Disease 72%
  • Inflammation 39%
  • Liver 34%
  36 Scopus citations

• RORγt-Raftlin1 complex regulates the pathogenicity of Th17 cells and colonic inflammation

  Singh, A. K., Kumar, R., Yin, J., Brooks, J. F., Kathania, M., Mukherjee, S., Kumar, J., Conlon, K. P., Basrur, V., Chen, Z., Han, X., Hooper, L. V., Burstein, E. & Venuprasad, K., Dec 2023, In: Nature communications. 14, 1, 4972.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Th17 Cells 100%
  • Virulence 73%
  • Phospholipid 70%
  • Lipid 58%
  • Inflammation 49%

• Saprophytic bacteria and fungi colonize stearoyl coenzyme-A desaturase-1 knockout skin

  Pyle, H. J., Artami, M., Edwards, M., Raj, P., Zhang, B., Arana, C. & Harris-Tryon, T. A., Jan 2023, In: Experimental Dermatology. 32, 1, p. 78-84 7 p.

  Research output: Contribution to journal › Article › peer-review

  • stearoyl-coenzyme A 100%
  • Fungi 52%
  • Lipid 40%
  • Bacteria 39%
  • Skin 32%
  2 Scopus citations

• Sex-based differences in effector cells of the adaptive immune system during Alzheimer's disease and related dementias

  Lutshumba, J., Wilcock, D. M., Monson, N. L. & Stowe, A. M., Aug 2023, In: Neurobiology of Disease. 184, 106202.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sex Characteristics 100%
  • Dementia 89%
  • Immune System 84%
  • Alzheimer Disease 82%
  • Precision Medicine 11%
  3 Scopus citations

• Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases

  Mosallanejad, K., Kennedy, S. N., Bahleda, K. M., Slavik, K. M., Zhou, W., Govande, A. A., Hancks, D. C., Kranzusch, P. J. & Kagan, J. C., Jan 2023, In: Science Immunology. 8, 79, eabp9765.

  Research output: Contribution to journal › Article › peer-review

  • GMP synthase (glutamine-hydrolyzing) 100%
  • cyclic guanosine monophosphate-adenosine monophosphate 89%
  • DNA 32%
  • mouse MB21D1 protein 14%
  • Primates 12%
  5 Scopus citations

• Staphylococcus aureus isolates from children with clinically differentiated osteomyelitis exhibit distinct transcriptomic signatures

  Hachem, A. A., Filkins, L. M., Kidane, Y. H., Raj, P., Tareen, N. G., Arana, C. A., Muthukrishnan, G. & Copley, L. A., Aug 2023, In: PloS one. 18, 8 August, e0288758.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Osteomyelitis 100%
  • Staphylococcus aureus 79%
  • Growth 46%
  • Child 40%
  • Virulence 30%

• Systemic immune parameters after prior radiation therapy in patients receiving immune checkpoint inhibitors

  Mundra, V., Yang, Y., von Itzstein, M. S., Fattah, F., Gonugunta, A. S., Hannan, R., Pop, L. M., Zhang, Y., Wang, Y., Sheffield, T., Xie, Y., Dowell, J. E., Homsi, J., Rashdan, S., Park, J., Li, Q. Z., Wakeland, E. K. & Gerber, D. E., Aug 2023, In: Translational Oncology. 34, 101689.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Radiotherapy 100%
  • Radiosurgery 28%
  • Complement C8 24%
  • Autoantibodies 24%
  • Immunotherapy 23%

• T-bet-expressing B cells contribute to the autoreactive plasma cell pool in Lyn^-/- mice

  Ottens, K., Schneider, J. & Satterthwaite, A. B., Aug 2023, In: European Journal of Immunology. 53, 8, 2250300.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Plasma Cells 100%
  • B-Lymphocytes 76%
  • Autoantibodies 52%
  • B-Lymphocyte Subsets 35%
  • Systemic Lupus Erythematosus 26%
  1 Scopus citations

• T-cell tolerant fraction as a predictor of immune-related adverse events

  Ostmeyer, J., Park, J. Y., Von Itzstein, M. S., Hsiehchen, D., Fattah, F., Gwin, M., Catalan, R., Khan, S., Raj, P., Wakeland, E. K., Xie, Y. & Gerber, D. E., Aug 13 2023, In: Journal for ImmunoTherapy of Cancer. 11, 8, e006437.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • T-Cell Antigen Receptor 100%
  • T-Lymphocytes 97%
  • Area Under Curve 47%
  • Autoimmune Diseases 34%
  • Registries 31%
  1 Scopus citations

• The dual lipid desaturase/hydroxylase DEGS2 controls phytoceramide levels necessary to counter intestinal inflammation

  Song, R., Fond, A., Li, X., Tang, M., Zhan, X., Gordillo, R., Moresco, E. M. Y., Beutler, B. & Turer, E. E., Sep 2023, In: DMM Disease Models and Mechanisms. 16, 9, dmm050043.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Phytoceramide 100%
  • Dihydroceramide 59%
  • Mixed Function Oxygenases 56%
  • Colitis 51%
  • dihydroceramide 42%

• The gut microbiota reprograms intestinal lipid metabolism through long noncoding RNA Snhg9

  Wang, Y., Wang, M., Chen, J., Li, Y., Kuang, Z., Dende, C., Raj, P., Quinn, G., Hu, Z., Srinivasan, T., Hassell, B., Ruhn, K. A., Behrendt, C. L., Liang, T., Dou, X., Song, Z. & Hooper, L. V., Aug 25 2023, In: Science. 381, 6660, p. 851-857 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Small Nucleolar RNA 100%
  • Long Noncoding RNA 74%
  • Gastrointestinal Microbiome 68%
  • Lipid Metabolism 66%
  • Peroxisomes 43%
  13 Scopus citations