Research output per year
Research output per year
- 1 - 50 out of 86 results
Search results
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2022
3D structure and in situ arrangements of CatSper channel in the sperm flagellum
Zhao, Y., Wang, H., Wiesehoefer, C., Shah, N. B., Reetz, E., Hwang, J. Y., Huang, X., Wang, T. E., Lishko, P. V., Davies, K. M., Wennemuth, G., Nicastro, D. & Chung, J. J., Dec 2022, In: Nature communications. 13, 1, 3439.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Three-dimensional flagella structures from animals’ closest unicellular relatives, the Choanoflagellates
Pinskey, J. M., Lagisetty, A., Gui, L., Phan, N., Reetz, E., Tavakoli, A., Fu, G. & Nicastro, D., Nov 2022, In: eLife. 11, e78133.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Triglyceride lipolysis triggers liquid crystalline phases in lipid droplets and alters the LD proteome
Rogers, S., Gui, L., Kovalenko, A., Zoni, V., Carpentier, M., Ramji, K., Mbarek, K. B., Bacle, A., Fuchs, P., Campomanes, P., Reetz, E., Speer, N. O., Reynolds, E., Thiam, A. R., Vanni, S., Nicastro, D. & Mike Henne, W., Nov 7 2022, In: Journal of Cell Biology. 221, 11, e202205053.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2021
Functional refolding of the penetration protein on a non-enveloped virus
Herrmann, T., Torres, R., Salgado, E. N., Berciu, C., Stoddard, D., Nicastro, D., Jenni, S. & Harrison, S. C., Feb 25 2021, In: Nature. 590, 7847, p. 666-670 5 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Proteomic analysis of microtubule inner proteins (MIPs) in Rib72 null Tetrahymena cells reveals functional MIPs
Fabritius, A. S., Bayless, B. A., Li, S., Stoddard, D., Heydeck, W., Ebmeier, C. C., Anderson, L., Gunnels, T., Nachiappan, C., Whittall, J. B., Old, W., Agard, D. A., Nicastro, D. & Winey, M., Nov 1 2021, In: Molecular biology of the cell. 32, 21, 0786.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Structural insights into the cause of human RSPH4A primary ciliary dyskinesia
Zhao, Y., Pinskey, J., Lin, J., Yin, W., Sears, P. R., Daniels, L. A., Zariwala, M. A., Knowles, M. R., Ostrowski, L. E. & Nicastro, D., May 27 2021, In: Molecular biology of the cell. 32, 12, p. 1202-1209 8 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Structural organization of the C1b projection within the ciliary central apparatus
Cai, K., Zhao, Y., Zhao, L., Phan, N., Hou, Y., Cheng, X., Witman, G. B. & Nicastro, D., Nov 2021, In: Journal of cell science. 134, 21, jcs254227.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Structural organization of the intermediate and light chain complex of Chlamydomonas ciliary I1 dynein
Fu, G., Scarbrough, C., Song, K., Phan, N., Wirschell, M. & Nicastro, D., Jun 2021, In: FASEB Journal. 35, 6, e21646.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2020
Absolute proteomic quantification reveals design principles of sperm flagellar chemosensation
Trötschel, C., Hamzeh, H., Alvarez, L., Pascal, R., Lavryk, F., Bönigk, W., Körschen, H. G., Müller, A., Poetsch, A., Rennhack, A., Gui, L., Nicastro, D., Strünker, T., Seifert, R. & Kaupp, U. B., Feb 17 2020, In: EMBO Journal. 39, 4, e102723.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Chlamydomonas PKD2 organizes mastigonemes, hair-like glycoprotein polymers on cilia
Liu, P., Lou, X., Wingfield, J. L., Lin, J., Nicastro, D. & Lechtreck, K., Jun 1 2020, In: Journal of Cell Biology. 219, 6, 202001122.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
Complexity and ultrastructure of infectious extracellular vesicles from cells infected by non-enveloped virus
Yang, J. E., Rossignol, E. D., Chang, D., Zaia, J., Forrester, I., Raja, K., Winbigler, H., Nicastro, D., Jackson, W. T. & Bullitt, E., Dec 1 2020, In: Scientific reports. 10, 1, 7939.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
In situ structure determination at nanometer resolution using TYGRESS
Song, K., Shang, Z., Fu, X., Lou, X., Grigorieff, N. & Nicastro, D., Feb 1 2020, In: Nature methods. 17, 2, p. 201-208 8 p.Research output: Contribution to journal › Article › peer-review
41 Scopus citations -
2019
Heterotrophic carbon metabolism and energy acquisition in Candidatus Thioglobus singularis strain PS1, a member of the SUP05 clade of marine Gammaproteobacteria
Spietz, R. L., Lundeen, R. A., Zhao, X., Nicastro, D., Ingalls, A. E. & Morris, R. M., Jul 2019, In: Environmental Microbiology. 21, 7, p. 2391-2401 11 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Ionotropic Receptors Specify the Morphogenesis of Phasic Sensors Controlling Rapid Thermal Preference in Drosophila
Budelli, G., Ni, L., Berciu, C., van Giesen, L., Knecht, Z. A., Chang, E. C., Kaminski, B., Silbering, A. F., Samuel, A., Klein, M., Benton, R., Nicastro, D. & Garrity, P. A., Feb 20 2019, In: Neuron. 101, 4, p. 738-747.e3Research output: Contribution to journal › Article › peer-review
Open Access57 Scopus citations -
Mdm1 maintains endoplasmic reticulum homeostasis by spatially regulating lipid droplet biogenesis
Hariri, H., Speer, N., Bowerman, J., Rogers, S., Fu, G., Reetz, E., Datta, S., Feathers, J. R., Ugrankar, R., Nicastro, D. & Henne, W. M., 2019, In: Journal of Cell Biology. 218, 4, p. 1319-1334 16 p.Research output: Contribution to journal › Article › peer-review
Open Access80 Scopus citations -
Membrane bridging by munc13-1 is crucial for neurotransmitter release
Quade, B., Camacho, M., Zhao, X., Orlando, M., Trimbuch, T., Xu, J., Li, W., Nicastro, D., Rosenmund, C. & Rizo, J., Feb 2019, In: eLife. 8, e42806.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations -
Morphological plasticity in a sulfur-oxidizing marine bacterium from the SUP05 clade enhances dark carbon fixation
Shah, V., Zhao, X., Lundeen, R. A., Ingalls, A. E., Nicastro, D. & Morris, R. M., May 1 2019, In: mBio. 10, 3, e00216-19.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
PACRG and FAP20 form the inner junction of axonemal doublet microtubules and regulate ciliary motility
Dymek, E. E., Lin, J., Fu, G., Porter, M. E., Nicastro, D. & Smith, E. F., Jul 15 2019, In: Molecular biology of the cell. 30, 15, p. 1805-1816 12 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Scaffold subunits support associated subunit assembly in the Chlamydomonas ciliary nexin-dynein regulatory complex
Gui, L., Song, K., Tritschler, D., Bower, R., Yan, S., Dai, A., Augspurger, K., Sakizadeh, J., Grzemska, M., Ni, T., Porter, M. E. & Nicastro, D., Nov 12 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 46, p. 23152-23162 11 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
2018
Asymmetric distribution and spatial switching of dynein activity generates ciliary motility
Lin, J. & Nicastro, D., Apr 27 2018, In: Science. 360, 6387, eaar1968.Research output: Contribution to journal › Article › peer-review
Open Access154 Scopus citations -
Cellular Uptake of A Taurine-Modified, Ester Bond-Decorated D-Peptide Derivative via Dynamin-Based Endocytosis and Macropinocytosis
Zhou, J., Du, X., Berciu, C., Del Signore, S. J., Chen, X., Yamagata, N., Rodal, A. A., Nicastro, D. & Xu, B., Feb 7 2018, In: Molecular Therapy. 26, 2, p. 648-658 11 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Ciliary proteins Fap43 and Fap44 interact with each other and are essential for proper cilia and flagella beating
Urbanska, P., Joachimiak, E., Bazan, R., Fu, G., Poprzeczko, M., Fabczak, H., Nicastro, D. & Wloga, D., Dec 1 2018, In: Cellular and Molecular Life Sciences. 75, 24, p. 4479-4493 15 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
DRC2/CCDC65 is a central hub for assembly of the nexin–dynein regulatory complex and other regulators of ciliary and flagellar motility
Bower, R., Tritschler, D., VanderWaal Mills, K., Heuser, T., Nicastro, D. & Portera, M. E., Jan 15 2018, In: Molecular biology of the cell. 29, 2, p. 137-153 17 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Tetrahymena RIB72A and RIB72B are microtubule inner proteins in the ciliary doublet microtubules
Stoddard, D., Zhao, Y., Bayless, B. A., Gui, L., Louka, P., Dave, D., Suryawanshi, S., Tomasi, R. F. X., Dupuis-Williams, P., Baroud, C. N., Gaertig, J., Winey, M. & Nicastro, D., Oct 15 2018, In: Molecular biology of the cell. 29, 21, p. 2566-2577 12 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
The I1 dynein-associated tether and tether head complex is a conserved regulator of ciliary motility
Fu, G., Wang, Q., Phan, N., Urbanska, P., Joachimiak, E., Lin, J., Wloga, D. & Nicastro, D., May 1 2018, In: Molecular biology of the cell. 29, 9, p. 1048-1059 12 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
The IDA3 adapter, required for intraflagellar transport of I1 dynein, is regulated by ciliary length
Hunter, E. L., Lechtreck, K., Fu, G., Hwang, J., Lin, H., Gokhale, A., Alford, L. M., Lewis, B., Yamamoto, R., Kamiya, R., Yang, F., Nicastro, D., Dutcher, S. K., Wirschell, M., Sale, W. S. & Holzbaur, E., Apr 15 2018, In: Molecular biology of the cell. 29, 8, p. 886-896 11 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
2017
Centriolar remodeling underlies basal body maturation during ciliogenesis in Caenorhabditis elegans
Nechipurenko, I. V., Berciu, C., Sengupta, P. & Nicastro, D., Apr 15 2017, In: eLife. 6, e25686.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Three-dimensional structure of the ultraoligotrophic marine bacterium "Candidatus pelagibacter ubique"
Zhao, X., Schwartz, C. L., Pierson, J., Giovannoni, S. J., McIntosh, J. R. & Nicastro, D., 2017, In: Applied and environmental microbiology. 83, 3, e02807-16.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
2016
Enzyme-Instructed Self-Assembly for Spatiotemporal Profiling of the Activities of Alkaline Phosphatases on Live Cells
Zhou, J., Du, X., Berciu, C., He, H., Shi, J., Nicastro, D. & Xu, B., Aug 11 2016, In: Chem. 1, 2, p. 246-263 18 p.Research output: Contribution to journal › Article › peer-review
Open Access132 Scopus citations -
The nexin link and B-tubule glutamylation maintain the alignment of outer doublets in the ciliary axoneme
Alford, L. M., Stoddard, D., Li, J. H., Hunter, E. L., Tritschler, D., Bower, R., Nicastro, D., Porter, M. E. & Sale, W. S., Jun 1 2016, In: Cytoskeleton. 73, 7, p. 331-340 10 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
2015
Assembly of actin filaments and microtubules in Nwk F-BAR-induced membrane deformations
Kelley, C. F., Becalska, A. N., Berciu, C., Nicastro, D. & Rodal, A. A., 2015, In: Communicative and Integrative Biology. 8, 2, p. 1-5 5 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
ATP Consumption of Eukaryotic Flagella Measured at a Single-Cell Level
Chen, D. T. N., Heymann, M., Fraden, S., Nicastro, D. & Dogic, Z., Dec 15 2015, In: Biophysical journal. 109, 12, p. 2562-2573 12 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
DRC3 connects the N-DRC to dynein g to regulate flagellar waveform
Awata, J., Song, K., Lin, J., King, S. M., Sanderson, M. J., Nicastro, D. & Witman, G. B., Aug 1 2015, In: Molecular biology of the cell. 26, 15, p. 2788-2800 13 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
FAP206 is a microtubule-docking adapter for ciliary radial spoke 2 and dynein c
Vasudevan, K. K., Song, K., Alford, L. M., Sale, W. S., Dymek, E. E., Smith, E. F., Hennessey, T., Joachimiak, E., Urbanska, P., Wloga, D., Dentler, W., Nicastro, D. & Gaertig, J., Feb 15 2015, In: Molecular biology of the cell. 26, 4, p. 696-710 15 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
In situ localization of N and C termini of subunits of the flagellar nexin-dynein regulatory complex (N-DRC) using SNAP tag and cryo-electron tomography
Song, K., Awata, J., Tritschler, D., Bower, R., Witman, G. B., Porter, M. E. & Nicastro, D., Feb 27 2015, In: Journal of Biological Chemistry. 290, 9, p. 5341-5353 13 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Membrane Charge Directs the Outcome of F-BAR Domain Lipid Binding and Autoregulation
Kelley, C. F., Messelaar, E. M., Eskin, T. L., Wang, S., Song, K., Vishnia, K., Becalska, A. N., Shupliakov, O., Hagan, M. F., Danino, D., Sokolova, O. S., Nicastro, D. & Rodal, A. A., Dec 22 2015, In: Cell Reports. 13, 11, p. 2597-2609 13 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
The CSC proteins FAP61 and FAP251 build the basal substructures of radial spoke 3 in cilia
Urbanska, P., Song, K., Joachimiak, E., Krzemien-Ojak, L., Koprowski, P., Hennessey, T., Jerka-Dziadosz, M., Fabczak, H., Gaertig, J., Nicastro, D. & Wloga, D., Apr 15 2015, In: Molecular biology of the cell. 26, 8, p. 1463-1475 13 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
2014
A high-resolution morphological and ultrastructural map of anterior sensory cilia and glia in Caenorhabditis elegans
Doroquez, D. B., Berciu, C., Anderson, J. R., Sengupta, P. & Nicastro, D., Mar 25 2014, In: eLife. 2014, 3, e01948.Research output: Contribution to journal › Article › peer-review
Open Access131 Scopus citations -
Critical roles for multiple formins during cardiac myofibril development and repair
Rosado, M., Barber, C. F., Berciu, C., Feldman, S., Birren, S. J., Nicastro, D. & Goode, B. L., Mar 15 2014, In: Molecular biology of the cell. 25, 6, p. 811-827 17 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Cryo-electron tomography reveals ciliary defects underlying human RSPH1 primary ciliary dyskinesia
Lin, J., Yin, W., Smith, M. C., Song, K., Leigh, M. W., Zariwala, M. A., Knowles, M. R., Ostrowski, L. E. & Nicastro, D., 2014, In: Nature communications. 5, 5727.Research output: Contribution to journal › Article › peer-review
Open Access107 Scopus citations -
Insights into the structure and function of ciliary and flagellar doublet microtubules: Tektins, Ca2+-binding proteins, and stable protofilaments
Linck, R., Fu, X., Lin, J., Ouch, C., Schefter, A., Steffen, W., Warren, P. & Nicastro, D., Jun 20 2014, In: Journal of Biological Chemistry. 289, 25, p. 17427-17444 18 p.Research output: Contribution to journal › Article › peer-review
Open Access63 Scopus citations -
Membrane deformation and scission by the HSV-1 nuclear egress complex
Bigalke, J. M., Heuser, T., Nicastro, D. & Heldwein, E. E., Jun 11 2014, In: Nature communications. 5, 4131.Research output: Contribution to journal › Article › peer-review
Open Access113 Scopus citations -
Robust excitons inhabit soft supramolecular nanotubes
Eisele, D. M., Arias, D. H., Fu, X., Bloemsma, E. A., Steiner, C. P., Jensen, R. A., Rebentrost, P., Eisele, H., Tokmakoff, A., Lloyd, S., Nelson, K. A., Nicastro, D., Knoester, J. & Bawendi, M. G., Aug 19 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 33, p. E3367-E3375Research output: Contribution to journal › Article › peer-review
Open Access96 Scopus citations -
Structural Correlates of Rotavirus Cell Entry
Abdelhakim, A. H., Salgado, E. N., Fu, X., Pasham, M., Nicastro, D., Kirchhausen, T. & Harrison, S. C., Sep 1 2014, In: PLoS pathogens. 10, 9Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Structural mechanism of the dynein power stroke
Lin, J., Okada, K., Raytchev, M., Smith, M. C. & Nicastro, D., 2014, In: Nature cell biology. 16, 5, p. 479-485 7 p.Research output: Contribution to journal › Article › peer-review
106 Scopus citations -
2013
Conserved structural motifs in the central pair complex of eukaryotic flagella
Carbajal-González, B. I., Heuser, T., Fu, X., Lin, J., Smith, B. W., Mitchell, D. R. & Nicastro, D., Feb 2013, In: Cytoskeleton. 70, 2, p. 101-120 20 p.Research output: Contribution to journal › Article › peer-review
Open Access69 Scopus citations -
Formation of membrane ridges and scallops by the F-BAR protein nervous wreck
Becalska, A. N., Kelley, C. F., Berciu, C., Stanishneva-Konovalova, T. B., Fu, X., Wang, S., Sokolova, O. S., Nicastro, D. & Rodal, A. A., Aug 1 2013, In: Molecular biology of the cell. 24, 15, p. 2406-2418 13 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
Probing nanoscale self-assembly of nonfluorescent small molecules inside live mammalian cells
Gao, Y., Berciu, C., Kuang, Y., Shi, J., Nicastro, D. & Xu, B., Oct 22 2013, In: ACS Nano. 7, 10, p. 9055-9063 9 p.Research output: Contribution to journal › Article › peer-review
Open Access62 Scopus citations -
The MIA complex is a conserved and novel dynein regulator essential for normal ciliary motility
Yamamoto, R., Song, K., Yanagisawa, H. A., Fox, L., Yagi, T., Wirschell, M., Hirono, M., Kamiya, R., Nicastro, D. & Sale, W. S., Apr 15 2013, In: Journal of Cell Biology. 201, 2, p. 263-278 16 p.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations -
2012
Cryoelectron tomography reveals doublet-specific structures and unique interactions in the I1 dynein
Heuser, T., Barber, C. F., Lin, J., Krell, J., Rebesco, M., Porter, M. E. & Nicastro, D., Jul 24 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 30, p. E2067-E2076Research output: Contribution to journal › Article › peer-review
Open Access80 Scopus citations