Research output per year
Research output per year
- 43 results
Search results
-
2021
Changes in the brain transcriptome after DNA Aβ42 trimer immunization in a 3xTg-AD mouse model
Lambracht-Washington, D., Fu, M., Hynan, L. S. & Rosenberg, R. N., Jan 2021, In: Neurobiology of Disease. 148, 105221.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2018
Active full-length DNA Aβ42 immunization in 3xTg-AD mice reduces not only amyloid deposition but also tau pathology
Rosenberg, R. N., Fu, M. & Washington, D. L., Nov 20 2018, In: Alzheimer's Research and Therapy. 10, 1, 115.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Intradermal active full-length DNA Aβ42 immunization via electroporation leads to high anti-Aβ antibody levels in wild-type mice
Rosenberg, R. N., Fu, M. & Lambracht-Washington, D., Sep 15 2018, In: Journal of Neuroimmunology. 322, p. 15-25 11 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2017
Evaluation of a DNA Aβ42 vaccine in adult rhesus monkeys (Macaca mulatta): Antibody kinetics and immune profile after intradermal immunization with full-length DNA Aβ42 trimer
Lambracht-Washington, D., Fu, M., Frost, P. & Rosenberg, R. N., Apr 26 2017, In: Alzheimer's Research and Therapy. 9, 1, 30.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Evaluation of a DNA Aβ42 Vaccine in Aged NZW Rabbits: Antibody Kinetics and Immune Profile after Intradermal Immunization with Full-Length DNA Aβ42 Trimer
Lambracht-Washington, D., Fu, M., Wight-Carter, M., Riegel, M. & Rosenberg, R. N., 2017, In: Journal of Alzheimer's Disease. 57, 1, p. 97-112 16 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Laquinimod has no effects on brain volume or cellular CNS composition in the F1 3xTg-AD/C3H mouse model of Alzheimer's disease
Hussain, R. Z., Miller-Little, W. A., Lambracht-Washington, D., Jaramillo, T. C., Takahashi, M., Zhang, S., Fu, M., Cutter, G. R., Hayardeny, L., Powell, C. M., Rosenberg, R. N. & Stüve, O., Aug 15 2017, In: Journal of Neuroimmunology. 309, p. 100-110 11 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2016
A single amino acid substitution prevents recognition of a dominant human aquaporin-4 determinant in the context of HLA-DRB1-03:01 by a murine TCR
Arellano, B., Hussain, R., Miller-Little, W. A., Herndon, E., Lambracht-Washington, D., Eagar, T. N., Lewis, R., Healey, D., Vernino, S., Greenberg, B. M. & Stüve, O., Apr 2016, In: PloS one. 11, 4, e0152720.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2015
A noninflammatory immune response in aged DNA Aβ42-immunized mice supports its safety for possible use as immunotherapy in AD patients
Lambracht-Washington, D. & Rosenberg, R. N., Mar 1 2015, In: Neurobiology of Aging. 36, 3, p. 1274-1281 8 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Co-stimulation with TNF receptor superfamily 4/25 antibodies enhances in-vivo expansion of CD4+CD25+Foxp3+ T cells (Tregs) in a mouse study for active DNA Aβ42 immunotherapy
Lambracht-Washington, D. & Rosenberg, R. N., Jan 15 2015, In: Journal of Neuroimmunology. 278, p. 90-99 10 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2013
Advances in the development of vaccines for alzheimer's disease
Lambracht-Washington, D. & Rosenberg, R. N., 2013, In: Discovery Medicine. 15, 84, p. 319-326 8 p.Research output: Contribution to journal › Article › peer-review
71 Scopus citations -
A peptide prime-DNA boost immunization protocol provides significant benefits as a new generation Aβ42 DNA vaccine for Alzheimer disease
Lambracht-Washington, D., Qu, B. X., Fu, M., Anderson, L. D., Eagar, T. N., Stüve, O. & Rosenberg, R. N., Jan 15 2013, In: Journal of Neuroimmunology. 254, 1-2, p. 63-68 6 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
2012
Human aquaporin 4 281-300 is the immunodominant linear determinant in the context of HLA-DRB1*03:01: Relevance for diagnosing and monitoring patients with neuromyelitis optica
Arellano, B., Hussain, R., Zacharias, T., Yoon, J., David, C., Zein, S., Steinman, L., Forsthuber, T., Greenberg, B. M., Lambracht-Washington, D., Ritchie, A. M., Bennett, J. L. & Stüve, O., Sep 2012, In: Archives of neurology. 69, 9, p. 1125-1131 7 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
2011
DNA immunization against amyloid beta 42 has high potential as safe therapy for Alzheimer's disease as it diminishes antigen-specific Th1 and Th17 cell proliferation.
Lambracht-Washington, D., Qu, B. X., Fu, M., Anderson, L. D., Stüve, O., Eagar, T. N. & Rosenberg, R. N., Aug 2011, In: Cellular and Molecular Neurobiology. 31, 6, p. 867-874 8 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
Lymph node-derived donor encephalitogenic CD4+ T cells in C57BL/6 mice adoptive transfer experimental autoimmune encephalomyelitis highly express GM-CSF and T-bet
Cravens, P. D., Hussain, R. Z., Zacharias, T. E., Ben, L. H., Herndon, E., Vinnakota, R., Lambracht-Washington, D., Nessler, S., Zamvil, S. S., Eagar, T. N. & Stüve, O., Jun 24 2011, In: Journal of Neuroinflammation. 8, 73.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
2010
Analysis of three plasmid systems for use in DNA Aβ42 immunization as therapy for Alzheimer's disease
Qu, B. X., Lambracht-Washington, D., Fu, M., Eagar, T. N., Stüve, O. & Rosenberg, R. N., Jul 2010, In: Vaccine. 28, 32, p. 5280-5287 8 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
2009
DNA β-amyloid1-42 trimer immunization for alzheimer diseaseina wild-type mouse model
Lambracht-Washington, D., Qu, B. X., Fu, M., Eagar, T. N., Stüve, O. & Rosenberg, R. N., 2009, In: JAMA. 302, 16, p. 1796-1802 7 p.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
2008
Structure and expression of MHC class Ib genes of the central M region in rat and mouse: M4, M5, and M6
Lambracht-Washington, D., Moore, Y. F., Wonigeit, K. & Lindahl, K. F., Apr 2008, In: Immunogenetics. 60, 3-4, p. 131-145 15 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
2007
Antigen specificity of clonally expanded and receptor edited cerebrospinal fluid B cells from patients with relapsing remitting MS
Washington, D. L., O'Connor, K. C., Cameron, E. M., Jowdry, A., Ward, E. S., Frohman, E., Racke, M. K. & Monson, N. L., May 2007, In: Journal of Neuroimmunology. 186, 1-2, p. 164-176 13 p.Research output: Contribution to journal › Article › peer-review
46 Scopus citations -
Cerebrospinal fluid B cells from multiple sclerosis patients are subject to normal germinal center selection
Harp, C., Lee, J., Washington, D. L., Cameron, E., Olsen, G., Frohman, E., Racke, M. & Monson, N. L., Feb 2007, In: Journal of Neuroimmunology. 183, 1-2, p. 189-199 11 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
2004
Active MHC class Ib genes in rat are pseudogenes in the mouse
Lambracht-Washington, D. & Lindahl, K. F., May 2004, In: Immunogenetics. 56, 2, p. 118-121 4 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Murine MHC class Ib gene, H2-M2, encodes a conserved surface-expressed glycoprotein
Moore, Y. F., Lambracht-Washington, D., Tabaczewski, P. & Lindahl, K. F., Apr 2004, In: Immunogenetics. 56, 1, p. 1-11 11 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
RT1.L: A family of MHC class Ib genes of the rat major histocompatibility complex with a distinct promoter structure
Lambracht-Washington, D., Düvel, H., Hänisch, L., Dinkel, A. & Wonigeit, K., Apr 2004, In: Immunogenetics. 56, 1, p. 28-37 10 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
2002
Does the rat have an H2-D orthologue next to Bat1?
Lambracht-Washington, D. & Lindahl, K. F., 2002, In: Immunogenetics. 53, 12, p. 1039-1046 8 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
2000
Promoter structures suggest independent translocations of ancestral rat RT1.A and mouse H2-K class I genes
Lambracht-Washington, D., Fischer Lindahl, K. & Wonigeit, K., 2000, In: Immunogenetics. 51, 10, p. 873-877 5 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
1999
Gene order of the RT1.M region of the rat MHC exemplifies interspecies conservation with the mouse
Lambracht-Washington, D., Wonigeit, K. & Lindahl, K. F., May 1999, In: Transplantation proceedings. 31, 3, p. 1515-1516 2 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Myelin oligodendrocyte glycoprotein induces experimental autoimmune encephalomyelitis in the 'resistant' Brown Norway rat: Disease susceptibility is determined by MHC and MHC-linked effects on the B cell response
Stefferl, A., Brehm, U., Storch, M., Lambracht-Washington, D., Bourquin, C., Wonigeit, K., Lassmann, H. & Linington, C., Jul 1 1999, In: Journal of Immunology. 163, 1, p. 40-49 10 p.Research output: Contribution to journal › Article › peer-review
128 Scopus citations -
RT1-U: Identification of a novel, active, class Ib alloantigen of the rat MHC
Leong, L. Y. W., Le Rolle, A. F., Deverson, E. V., Powis, S. J., Larkins, A. P., Vaage, J. T., Stokland, A., Lambracht-Washington, D., Rolstad, B., Joly, E. & Butcher, G. W., Jan 15 1999, In: Journal of Immunology. 162, 2, p. 743-752 10 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
1998
A polymorphic microsatellite marker in the rat major histocompatibility complex class I gene, RT1.M4, and a new recombinant RT1 haplotype, r39
Lambracht-Washington, D., Shisa, H., Butcher, G. W. & Lindahl, K. F., 1998, In: Immunogenetics. 48, 6, p. 420-421 2 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Identification of an inhibitory MHC receptor on alloreactive rat natural killer cells
Naper, C., Ryan, J. C., Nakamura, M. C., Lambracht, D., Rolstad, B. & Vaage, J. T., Jan 1 1998, In: Journal of Immunology. 160, 1, p. 219-224 6 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
Lessons from rat models on the genetic basis of interindividual differences in lymphocyte phenotype
Wonigeit, K., Washington, D. & Hundrieser, J., 1998, In: Transplantation proceedings. 30, 5, p. 2341-2343 3 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
1997
Markers for interspecies relationship in the RT1 complex
Lambracht, D., Wonigeit, K., Howard, J. C. & Lindahl, K. F., 1997, In: Transplantation proceedings. 29, 3, p. 1665-1667 3 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
1996
Negative regulation of rat natural killer cell activity by major histocompatibility complex class I recognition
Kraus, E., Lambracht, D., Wonigeit, K. & Hünig, T., Nov 12 1996, In: European Journal of Immunology. 26, 11, p. 2582-2586 5 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
1995
Alloreactive natural killer cells in the rat: complex genetics of major histocompabitility complex control
Naper, C., Vaage, J. T., Lambracht, D., Løvik, G., Butcher, G. W., Wonigeit, K. & Rolstad, B., May 1995, In: European Journal of Immunology. 25, 5, p. 1249-1256 8 p.Research output: Contribution to journal › Article › peer-review
58 Scopus citations -
Mapping of H2-M homolog and MOG genes in the rat MHC
Lambracht, D., Prokop, C., Hedrich, H. J., Lindahl, K. F. & Wonigeit, K., Sep 1995, In: Immunogenetics. 42, 5, p. 418-421 4 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Rat RT1 orthologs of mouse H2-M class lb genes
Wang, C. R., Lambracht, D., Wonigeit, K., Howard, J. C. & Lindahl, K. F., May 1995, In: Immunogenetics. 42, 1, p. 63-67 5 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
RT1.A(1) and class I genes deleted in the mutant haplotype Im1 share a similar promoter region
Wonigeit, K. & Lambracht, D., 1995, In: Transplantation proceedings. 27, 2, p. 1522-1523 2 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Sequence analysis of the promoter regions of the classical class I gene RT1.Al and two other class I genes of the rat MHC
Lambracht, D. & Wonigeit, K., Apr 1 1995, In: Immunogenetics. 41, 6, p. 375-379 5 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
1994
Control of rat natural killer cell-mediated allorecognition by a major histocompatibility complex region encoding nonclassical class I antigens
Vaage, J. T., Naper, C., Løvik, G., Lambracht, D., Rehm, A., Hedrich, H. J., Wonigeit, K. & Rolstad, B., Aug 1 1994, In: Journal of Experimental Medicine. 180, 2, p. 641-651 11 p.Research output: Contribution to journal › Article › peer-review
83 Scopus citations -
1993
Characterization of a new recombinant RT1 haplotype (r37) in BN.1B/Pit rats
Wonigeit, K., Lambracht, D., Kunz, H., Gill, T. & Hedrich, H. J., Jan 1 1993, In: Transplantation Proceedings. 25, 5, p. 2763-2765 3 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Cloning of the RT1.L gene coding for a low polymorphic class I antigen in the rat
Lambracht, D., Schulze, F. & Wonigeit, K., Jan 1 1993, In: Transplantation proceedings. 25, 5, p. 2766-2767 2 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Deletion of major histocompatibility complex class I genes in a new mutant RT1 haplotype (Im3) defined in BN.1LM3/Han rats
Lambracht, D., Hedrich, H. J. & Wonigeit, K., 1993, In: Transplantation proceedings. 25, 5, p. 2756-2758 3 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
1990
Restriction fragment-length polymorphism analysis of a second laboratory-derived mutant RT1 haplotype
Lambracht, D., Hanisch, L., Wurst, W., Gunther, E. & Wonigeit, K., Dec 1 1990, In: Transplantation proceedings. 22, 6, p. 2512-2513 2 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
1989
Alloantigen-induced activation of nude rat lymphocytes results in a selective expansion of CD4+ cells
Schwinzer, R., Lambracht, D., Hedrich, H. J. & Wonigeit, K., 1989, In: Transplantation proceedings. 21, 2, p. 3249-3250 2 p.Research output: Contribution to journal › Article › peer-review