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  • 2013

    Streptomycin-induced inflammation enhances Escherichia coli gut colonization through nitrate respiration

    Spees, A. M., Wangdi, T., Lopez, C. A., Kingsbury, D. D., Xavier, M. N., Winter, S. E., Tsolis, R. M. & Bäumler, A. J., Jul 2 2013, In: mBio. 4, 4, e00430-13.

    Research output: Contribution to journalArticlepeer-review

    154 Scopus citations
  • T cell-derived b cell differentiation factor(s) effect on the isotype switch of murine b cells

    Isakson, P. C., Pure, E., Vitetta, E. S. & Krammer, P. H., Feb 1 2013, In: Journal of Immunology. 190, 3, p. 849-863 15 p.

    Research output: Contribution to journalArticlepeer-review

  • TH17 cell differentiation is regulated by the circadian clock

    Yu, X., Rollins, D., Ruhn, K. A., Stubblefield, J. J., Green, C. B., Kashiwada, M., Rothman, P. B., Takahashi, J. S. & Hooper, L. V., 2013, In: Science. 342, 6159, p. 727-730 4 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    325 Scopus citations
  • The acyl-homoserine lactone synthase YenI from Yersinia enterocolitica modulates virulence gene expression in enterohemorrhagic Escherichia coli O157: H7

    Nguyen, Y. N., Sheng, H., Dakarapu, R., Falck, J. R., Hovde, C. J. & Sperandio, V., Nov 2013, In: Infection and immunity. 81, 11, p. 4192-4199 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9 Scopus citations
  • The authors reply

    Choi, A. M. K., Ryter, S. W. & Levine, B., 2013, In: New England Journal of Medicine. 368, 19, p. 1845-1846 2 p.

    Research output: Contribution to journalArticlepeer-review

    964 Scopus citations
  • The Human Nuclear Poly(A)-Binding Protein Promotes RNA Hyperadenylation and Decay

    Bresson, S. M. & Conrad, N. K., Oct 2013, In: PLoS genetics. 9, 10, e1003893.

    Research output: Contribution to journalArticlepeer-review

    94 Scopus citations
  • The interacting Cra and KdpE regulators are involved in the expression of multiple virulence factors in enterohemorrhagic Escherichia coli

    Njoroge, J. W., Gruber, C. & Sperandio, V., Jun 2013, In: Journal of bacteriology. 195, 11, p. 2499-2508 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    36 Scopus citations
  • The TP0796 lipoprotein of Treponema pallidum is a bimetal-dependent FAD pyrophosphatase with a potential role in flavin homeostasis

    Deka, R. K., Brautigam, C. A., Liu, W. Z., Tomchick, D. R. & Norgard, M. V., Apr 19 2013, In: Journal of Biological Chemistry. 288, 16, p. 11106-11121 16 p.

    Research output: Contribution to journalArticlepeer-review

    23 Scopus citations
  • The ubiquitin ligase parkin mediates resistance to intracellular pathogens

    Manzanillo, P. S., Ayres, J. S., Watson, R. O., Collins, A. C., Souza, G., Rae, C. S., Schneider, D. S., Nakamura, K., Shiloh, M. U. & Cox, J. S., 2013, In: Nature. 501, 7468, p. 512-516 5 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    426 Scopus citations
  • TLR-independent neutrophil-derived IFN-γ is important for host resistance to intracellular pathogens

    Sturge, C. R., Benson, A., Raetz, M., Wilhelm, C. L., Mirpuri, J., Vitetta, E. S. & Yarovinsky, F., Jun 25 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 26, p. 10711-10716 6 p.

    Research output: Contribution to journalArticlepeer-review

    102 Scopus citations
  • Transcription factors mediate the enzymatic disassembly of promoter-bound 7sk snrnp to locally recruit p-tefb for transcription elongation

    McNamara, R., McCann, J., Gudipaty, S. A. & D'Orso, I., Dec 12 2013, In: Cell Reports. 5, 5, p. 1256-1268 13 p.

    Research output: Contribution to journalArticlepeer-review

    70 Scopus citations
  • Transepithelial migration of neutrophils into the lung requires TREM-1

    Klesney-Tait, J., Keck, K., Li, X., Gilfillan, S., Otero, K., Baruah, S., Meyerholz, D. K., Varga, S. M., Knudson, C. J., Moninger, T. O., Moreland, J., Zabner, J. & Colonna, M., Jan 2 2013, In: Journal of Clinical Investigation. 123, 1, p. 138-149 12 p.

    Research output: Contribution to journalArticlepeer-review

    122 Scopus citations
  • Transgenic expression of microRNA-185 causes a developmental arrest of T cells by targeting multiple genes including Mzb1

    Belkaya, S., Murray, S. E., Eitson, J. L., De La Morena, M. T., Forman, J. A. & Van Oers, N. S. C., Oct 18 2013, In: Journal of Biological Chemistry. 288, 42, p. 30752-30762 11 p.

    Research output: Contribution to journalArticlepeer-review

    35 Scopus citations
  • Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

    Hasan, M., Koch, J., Rakheja, D., Pattnaik, A. K., Brugarolas, J. B., Dozmorov, I., Levine, B., Wakeland, E. K., Lee-Kirsch, M. A. & Yan, N., Jan 2013, In: Nature immunology. 14, 1, p. 61-71 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    119 Scopus citations
  • Understanding the microbiota in the midst of Renaissance architecture and olive groves

    Guarner, F., Hooper, L. V. & Núñez, G., Feb 2013, In: Nature immunology. 14, 2, p. 101-105 5 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • Virulence and stress-related periplasmic protein (VisP) in bacterial/host associations

    Moreira, C. G., Herrera, C. M., Needham, B. D., Parker, C. T., Libby, S. J., Fang, F. C., Trent, M. S. & Sperandio, V., Jan 22 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 4, p. 1470-1475 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    41 Scopus citations
  • XBeclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism

    He, C., Wei, Y., Sun, K., Li, B., Dong, X., Zou, Z., Liu, Y., Kinch, L. N., Khan, S., Sinha, S., Xavier, R. J., Grishin, N. V., Xiao, G., Eskelinen, E. L., Scherer, P. E., Whistler, J. L. & Levine, B., Aug 29 2013, In: Cell. 154, 5, p. X1085-1099

    Research output: Contribution to journalArticlepeer-review

    127 Scopus citations
  • XEGFR-mediated beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance

    Wei, Y., Zou, Z., Becker, N., Anderson, M., Sumpter, R., Xiao, G., Kinch, L., Koduru, P., Christudass, C. S., Veltri, R. W., Grishin, N. V., Peyton, M., Minna, J., Bhagat, G. & Levine, B., Sep 12 2013, In: Cell. 154, 6, p. 1269 1 p.

    Research output: Contribution to journalArticlepeer-review

    431 Scopus citations
  • 2012

    Acidomonas methanolica-associated necrotizing lymphadenitis in a patient with chronic granulomatous disease

    Chase, J. M., Holland, S. M., Greenberg, D. E., Marshall-Batty, K., Zelazny, A. M. & Church, J. A., Dec 2012, In: Journal of Clinical Immunology. 32, 6, p. 1193-1196 4 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • A composite bacteriophage alters colonization by an intestinal commensal bacterium

    Duerkop, B. A., Clements, C. V., Rollins, D., Rodrigues, J. L. M. & Hooper, L. V., Oct 23 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 43, p. 17621-17626 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    182 Scopus citations
  • Activation of the RpoN-RpoS regulatory pathway during the enzootic life cycle of Borrelia burgdorferi

    Ouyang, Z., Narasimhan, S., Neelakanta, G., Kumar, M., Pal, U., Fikrig, E. & Norgard, M. V., 2012, In: BMC microbiology. 12, 44.

    Research output: Contribution to journalArticlepeer-review

    52 Scopus citations
  • Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation

    Wang, R. C., Wei, Y., An, Z., Zou, Z., Xiao, G., Bhagat, G., White, M., Reichelt, J. & Levine, B., Nov 16 2012, In: Science. 338, 6109, p. 956-959 4 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    604 Scopus citations
  • Autoantibodies contribute to the immunopathogenesis of experimental dry eye disease.

    Stern, M. E., Schaumburg, C. S., Siemasko, K. F., Gao, J., Wheeler, L. A., Grupe, D. A., De Paiva, C. S., Calder, V. L., Calonge, M., Niederkorn, J. Y. & Pflugfelder, S. C., Apr 2012, In: Investigative ophthalmology & visual science. 53, 4, p. 2062-2075 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    61 Scopus citations
  • Biophysical and bioinformatic analyses implicate the treponema pallidum tp34 lipoprotein (tp0971) in transition metal homeostasis

    Brautigam, C. A., Deka, R. K., Ouyang, Z., Machius, M., Knutsen, G., Tomchick, D. R. & Norgard, M. V., Oct 2012, In: Journal of bacteriology. 194, 24, p. 6771-6781 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    17 Scopus citations
  • C7L family of poxvirus host range genes inhibits antiviral activities induced by type I interferons and interferon regulatory factor 1

    Meng, X., Schoggins, J., Rose, L., Cao, J., Ploss, A., Rice, C. M. & Xiang, Y., Apr 2012, In: Journal of virology. 86, 8, p. 4538-4547 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    35 Scopus citations
  • Chemical Reporters for Monitoring RNA Synthesis and Poly(A) Tail Dynamics

    Grammel, M., Hang, H. & Conrad, N. K., May 2012, In: ChemBioChem. 13, 8, p. 1112-1115 4 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    55 Scopus citations
  • Chikungunya virus-induced autophagy delays caspase-dependent cell death

    Joubert, P. E., Werneke, S. W., de la Calle, C., Guivel-Benhassine, F., Giodini, A., Peduto, L., Levine, B., Schwartz, O., Lenschow, D. J. & Albert, M. L., May 7 2012, In: Journal of Experimental Medicine. 209, 5, p. 1029-1047 19 p.

    Research output: Contribution to journalArticlepeer-review

    162 Scopus citations
  • Correlative light and electron microscopy (CLEM) as a tool to visualize microinjected molecules and their eukaryotic sub-cellular targets

    Evan Reddick, L. & Alto, N. M., May 4 2012, In: Journal of Visualized Experiments. 63, p. 1 1 p., A2.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro

    Schoggins, J. W., Dorner, M., Feulner, M., Imanaka, N., Murphy, M. Y., Ploss, A. & Rice, C. M., Sep 4 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 36, p. 14610-14615 6 p.

    Research output: Contribution to journalArticlepeer-review

    151 Scopus citations
  • Endotoxin priming of neutrophils requires endocytosis and NADPH oxidase-dependent endosomal reactive oxygen species

    Lamb, F. S., Hook, J. S., Hilkin, B. M., Huber, J. N., Volk, A. P. D. & Moreland, J. G., Apr 6 2012, In: Journal of Biological Chemistry. 287, 15, p. 12395-12404 10 p.

    Research output: Contribution to journalArticlepeer-review

    38 Scopus citations
  • Enterohemorrhagic escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE

    Njoroge, J. & Sperandio, V., Feb 2012, In: Infection and immunity. 80, 2, p. 688-703 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    56 Scopus citations
  • Ethanolamine controls expression of genes encoding components involved in interkingdom signaling and virulence in enterohemorrhagic escherichia coli O157:H7

    Kendall, M. M., Gruber, C. C., Parker, C. T. & Sperandio, V., 2012, In: mBio. 3, 3, e00050-12.

    Research output: Contribution to journalArticlepeer-review

    132 Scopus citations
  • Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

    He, C., Bassik, M. C., Moresi, V., Sun, K., Wei, Y., Zou, Z., An, Z., Loh, J., Fisher, J., Sun, Q., Korsmeyer, S., Packer, M., May, H. I., Hill, J. A., Virgin, H. W., Gilpin, C., Xiao, G., Bassel-Duby, R. S., Scherer, P. E. & Levine, B., Jan 26 2012, In: Nature. 481, 7382, p. 511-515 5 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    918 Scopus citations
  • Exercise induces autophagy in peripheral tissues and in the brain

    He, C., Sumpter, R. & Levine, B., Oct 2012, In: Autophagy. 8, 10, p. 1548-1551 4 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    190 Scopus citations
  • Express Your LOV: An Engineered Flavoprotein as a Reporter for Protein Expression and Purification

    Gawthorne, J. A., Reddick, L. E., Akpunarlieva, S. N., Beckham, K. S. H., Christie, J. M., Alto, N. M., Gabrielsen, M. & Roe, A. J., Dec 27 2012, In: PloS one. 7, 12, e52962.

    Research output: Contribution to journalArticlepeer-review

    23 Scopus citations
  • Global landscape of HIV-human protein complexes

    Jäger, S., Cimermancic, P., Gulbahce, N., Johnson, J. R., McGovern, K. E., Clarke, S. C., Shales, M., Mercenne, G., Pache, L., Li, K., Hernandez, H., Jang, G. M., Roth, S. L., Akiva, E., Marlett, J., Stephens, M., D'Orso, I., Fernandes, J., Fahey, M., Mahon, C., & 17 othersOĝdonoghue, A. J., Todorovic, A., Morris, J. H., Maltby, D. A., Alber, T., Cagney, G., Bushman, F. D., Young, J. A., Chanda, S. K., Sundquist, W. I., Kortemme, T., Hernandez, R. D., Craik, C. S., Burlingame, A., Sali, A., Frankel, A. D. & Krogan, N. J., Jan 19 2012, In: Nature. 481, 7381, p. 365-370 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    555 Scopus citations
  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H. M., Al-Zeer, M. A., Albert, M. L., Albin, R. L., Alegre-Abarrategui, J., & 1,249 othersAleo, M. F., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A. O., Andrieu-Abadie, N., Anantharam, V., Ann, D. K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J. P., Asanuma, K., Asare, N. Y. O., Ashida, H., Askanas, V., Askew, D. S., Auberger, P., Baba, M., Backues, S. K., Baehrecke, E. H., Bahr, B. A., Bai, X. Y., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Bamber, B. A., Bampton, E. T. W., Bánhegyi, G., Bartholomew, C. R., Bassham, D. C., Bast, R. C., Batoko, H., Bay, B. H., Beau, I., Béchet, D. M., Begley, T. J., Behl, C., Behrends, C., Bekri, S., Bellaire, B., Bendall, L. J., Benetti, L., Berliocchi, L., Bernardi, H., Bernassola, F., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Blum, J. S., Boise, L. H., Bonaldo, P., Boone, D. L., Bornhauser, B. C., Bortoluci, K. R., Bossis, I., Bost, F., Bourquin, J. P., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N. R., Brancolini, C., Brech, A., Brenman, J. E., Brennand, A., Bresnick, E. H., Brest, P., Bridges, D., Bristol, M. L., Brookes, P. S., Brown, E. J., Brumell, J. H., Brunetti-Pierri, N., Brunk, U. T., Bulman, D. E., Bultman, S. J., Bultynck, G., Burbulla, L. F., Bursch, W., Butchar, J. P., Buzgariu, W., Bydlowski, S. P., Cadwell, K., Cahová, M., Cai, D., Cai, J., Cai, Q., Calabretta, B., Calvo-Garrido, J., Camougrand, N., Campanella, M., Campos-Salinas, J., Candi, E., Cao, L., Caplan, A. B., Carding, S. R., Cardoso, S. M., Carew, J. S., Carlin, C. R., Carmignac, V., Carneiro, L. A. M., Carra, S., Caruso, R. A., Casari, G., Casas, C., Castino, R., Cebollero, E., Cecconi, F., Celli, J., Chaachouay, H., Chae, H. J., Chai, C. Y., Chan, D. C., Chan, E. Y., Chang, R. C. C., Che, C. M., Chen, C. C., Chen, G. C., Chen, G. Q., Chen, M., Chen, Q., Chen, S. S. L., Chen, W., Chen, X., Chen, X., Chen, X., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y. J., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, Y., Cheong, H., Cheong, J. H., Cherry, S., Chess-Williams, R., Cheung, Z. H., Chevet, E., Chiang, H. L., Chiarelli, R., Chiba, T., Chin, L. S., Chiou, S. H., Chisari, F. V., Cho, C. H., Cho, D. H., Choi, A. M. K., Choi, D., Choi, K. S., Choi, M. E., Chouaib, S., Choubey, D., Choubey, V., Chu, C. T., Chuang, T. H., Chueh, S. H., Chun, T., Chwae, Y. J., Chye, M. L., Ciarcia, R., Ciriolo, M. R., Clague, M. J., Clark, R. S. B., Clarke, P. G. H., Clarke, R., Codogno, P., Coller, H. A., Colombo, M. I., Comincini, S., Condello, M., Condorelli, F., Cookson, M. R., Coombs, G. H., Coppens, I., Corbalan, R., Cossart, P., Costelli, P., Costes, S., Coto-Montes, A., Couve, E., Coxon, F. P., Cregg, J. M., Crespo, J. L., Cronjé, M. J., Cuervo, A. M., Cullen, J. J., Czaja, M. J., D'Amelio, M., Darfeuille-Michaud, A., Davids, L. M., Davies, F. E., De Felici, M., De Groot, J. F., De Haan, C. A. M., De Martino, L., De Milito, A., De Tata, V., Debnath, J., Degterev, A., Dehay, B., Delbridge, L. M. D., Demarchi, F., Deng, Y. Z., Dengjel, J., Dent, P., Denton, D., Deretic, V., Desai, S. D., Devenish, R. J., Di Gioacchino, M., Di Paolo, G., Di Pietro, C., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dikic, I., Dinesh-Kumar, S. P., Ding, W. X., Distelhorst, C. W., Diwan, A., Djavaheri-Mergny, M., Dokudovskaya, S., Dong, Z., Dorsey, F. C., Dosenko, V., Dowling, J. J., Doxsey, S., Dreux, M., Drew, M. E., Duan, Q., Duchosal, M. A., Duff, K., Dugail, I., Durbeej, M., Duszenko, M., Edelstein, C. L., Edinger, A. L., Egea, G., Eichinger, L., Eissa, N. T., Ekmekcioglu, S., El-Deiry, W. S., Elazar, Z., Elgendy, M., Ellerby, L. M., Er Eng, K., Engelbrecht, A. M., Engelender, S., Erenpreisa, J., Escalante, R., Esclatine, A., Eskelinen, E. L., Espert, L., Espina, V., Fan, H., Fan, J., Fan, Q. W., Fan, Z., Fang, S., Fang, Y., Fanto, M., Fanzani, A., Farkas, T., Farré, J. C., Faure, M., Fechheimer, M., Feng, C. G., Feng, J., Feng, Q., Feng, Y., Fésüs, L., Feuer, R., Figueiredo-Pereira, M. E., Fimia, G. M., Fingar, D. C., Finkbeiner, S., Finkel, T., Finley, K. D., Fiorito, F., Fisher, E. A., Fisher, P. B., Flajolet, M., Florez-McClure, M. L., Florio, S., Fon, E. A., Fornai, F., Fortunato, F., Fotedar, R., Fowler, D. H., Fox, H. S., Franco, R., Frankel, L. B., Fransen, M., Fuentes, J. M., Fueyo, J., Fujii, J., Fujisaki, K., Fujita, E., Fukuda, M., Furukawa, R. H., Gaestel, M., Gailly, P., Gajewska, M., Galliot, B., Galy, V., Ganesh, S., Ganetzky, B., Ganley, I. G., Gao, F. B., Gao, G. F., Gao, J., Garcia, L., Garcia-Manero, G., Garcia-Marcos, M., Garmyn, M., Gartel, A. L., Gatti, E., Gautel, M., Gawriluk, T. R., Gegg, M. E., Geng, J., Germain, M., Gestwicki, J. E., Gewirtz, D. A., Ghavami, S., Ghosh, P., Giammarioli, A. M., Giatromanolaki, A. N., Gibson, S. B., Gilkerson, R. W., Ginger, M. L., Ginsberg, H. N., Golab, J., Goligorsky, M. S., Golstein, P., Gomez-Manzano, C., Goncu, E., Gongora, C., Gonzalez, C. D., Gonzalez, R., González-Estévez, C., González-Polo, R. A., Gonzalez-Rey, E., Gorbunov, N. V., Gorski, S., Goruppi, S., Gottlieb, R. A., Gozuacik, D., Granato, G. E., Grant, G. D., Green, K. N., Gregorc, A., Gros, F., Grose, C., Grunt, T. W., Gual, P., Guan, J. L., Guan, K. L., Guichard, S. M., Gukovskaya, A. S., Gukovsky, I., Gunst, J., Gustafsson, A. B., Halayko, A. J., Hale, A. N., Halonen, S. K., Hamasaki, M., Han, F., Han, T., Hancock, M. K., Hansen, M., Harada, H., Harada, M., Hardt, S. E., Harper, J. W., Harris, A. L., Harris, J., Harris, S. 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    Open Access
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  • Inhibition of HIV-1 particle assembly by 2′,3′-cyclic- nucleotide 3′-Phosphodiesterase

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    Open Access
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