BE-Biomedical Engineering

Research output

Research output per year 2005 2021 2022 2023 2024 2024

• 33 Article
• 4 Review article
• 2 Conference contribution
• 2 Comment/debate
• 5 More
  • 2 Letter
  • 1 Conference article
  • 1 Editorial
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2024

  Automated segmentation of phases, steps, and tasks in laparoscopic cholecystectomy using deep learning

  Hegde, S. R., Namazi, B., Iyengar, N., Cao, S., Desir, A., Marques, C., Mahnken, H., Dumas, R. P. & Sankaranarayanan, G., Jan 2024, In: Surgical endoscopy. 38, 1, p. 158-170 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Deep Learning 100%
  • Laparoscopic Cholecystectomy 82%
  • Datasets 28%
  • Bile 18%
  • Hemorrhage 11%
  1 Scopus citations

• Beyond synthetic aperture focusing: deconvolution-based elevation resolution enhancement using simulated point spread function for linear array-based three-dimensional photoacoustic imaging

  Tang, Y., Lesniak, W. G., Gao, S., Wu, Y., Pomper, M. G. & Zhang, H. K., Mar 1 2024, In: Biomedical Optics Express. 15, 3, p. 1847-1860 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • synthetic apertures 100%
  • Three-Dimensional Imaging 92%
  • linear arrays 88%
  • point spread functions 84%
  • augmentation 47%

• Comparison of Multiple Segmentation Methods for Volumetric Delineation of Primary Prostate Cancer with Prostate-Specific Membrane Antigen-Targeted ¹⁸F-DCFPyL PET/CT

  Wang, F., Liu, C., Vidal, I., Mana-Ay, M., Voter, A. F., Solnes, L. B., Ross, A. E., Gafita, A., Schaeffer, E. M., Bivalacqua, T. J., Pienta, K. J., Pomper, M. G., Lodge, M. A., Song, D. Y., Oldan, J. D., Allaf, M. E., De Marzo, A. M., Sheikhbahaei, S., Gorin, M. A. & Rowe, S. P., Jan 1 2024, In: Journal of Nuclear Medicine. 65, 1, p. 87-93 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acid 100%
  • Prostate-Specific Antigen 51%
  • Tumor Burden 47%
  • Prostatic Neoplasms 39%
  • Membranes 29%

• Deep Semisupervised Transfer Learning for Fully Automated Whole-Body Tumor Quantification and Prognosis of Cancer on PET/CT

  Leung, K. H., Rowe, S. P., Sadaghiani, M. S., Leal, J. P., Mena, E., Choyke, P. L., Du, Y. & Pomper, M. G., 2024, In: Journal of Nuclear Medicine. 65, 4, p. 643-650 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Supervised Machine Learning 100%
  • Machine Learning 70%
  • Prostate-Specific Antigen 64%
  • Prostatic Neoplasms 49%
  • Positron Emission Tomography Computed Tomography 41%

• Determining topical product bioequivalence with stimulated Raman scattering microscopy

  Iliopoulos, F., Tu, D., Pence, I. J., Li, X., Ghosh, P., Luke, M. C., Raney, S. G., Rantou, E. & Evans, C. L., Mar 2024, In: Journal of Controlled Release. 367, p. 864-876 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Nonlinear Optical Microscopy 100%
  • Therapeutic Equivalency 74%
  • Bioavailability 42%
  • Skin 32%
  • Drug 30%
  1 Scopus citations

• Development of New CD38 Targeted Peptides for Cancer Imaging

  Zheleznyak, A., Tang, R., Duncan, K., Manion, B., Liang, K., Xu, B., Vanover, A., Ghai, A., Prior, J., Lees, S., Achilefu, S., Kelly, K. & Shokeen, M., 2024, (Accepted/In press) In: Molecular Imaging and Biology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Multiple Myeloma 100%
  • 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane 81%
  • Peptides 64%
  • Positron-Emission Tomography 40%
  • Radiopharmaceuticals 34%

• Nanoparticle targeting of neutrophil glycolysis prevents lung ischemia-reperfusion injury

  Liao, F., Scozzi, D., Zhou, D., Maksimos, M., Diedrich, C., Cano, M., Tague, L. K., Liu, Z., Haspel, J. A., Leonard, J. M., Li, W., Krupnick, A. S., Wong, B. W., Kreisel, D., Azab, A. K. & Gelman, A. E., 2024, (Accepted/In press) In: American Journal of Transplantation.

  Research output: Contribution to journal › Article › peer-review

  • Glycolysis 100%
  • Reperfusion Injury 92%
  • Nanoparticles 84%
  • Deoxyglucose 78%
  • Neutrophils 74%

• Prognostic Performance of RECIP 1.0 Based on [18F]PSMA-1007 PET in Prostate Cancer Patients Treated with [177Lu]Lu-PSMA I&T

  Hartrampf, P. E., Hüttmann, T., Seitz, A. K., Kübler, H., Serfling, S. E., Higuchi, T., Schlötelburg, W., Michalski, K., Gafita, A., Rowe, S. P., Pomper, M. G., Buck, A. K. & Werner, R. A., 2024, In: Journal of Nuclear Medicine. 65, 4, p. 560-565 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Prostate-Specific Antigen 100%
  • Prostatic Neoplasms 77%
  • Membranes 58%
  • Castration 24%
  • Tumor Burden 21%

• The development of a deep learning model for automated segmentation of the robotic pancreaticojejunostomy

  Al Abbas, A. I., Namazi, B., Radi, I., Alterio, R., Abreu, A. A., Rail, B., Polanco, P. M., Zeh, H. J., Hogg, M. E., Zureikat, A. H. & Sankaranarayanan, G., 2024, (Accepted/In press) In: Surgical endoscopy.

  Research output: Contribution to journal › Article › peer-review

  • Pancreaticojejunostomy 100%
  • Deep Learning 92%
  • Robotics 70%
  • Pancreaticoduodenectomy 31%
  • Pancreatic Fistula 17%

• Validity and reliability evidence support task-specific metrics for laparoscopic fundoplication

  Desir, A., Marques, C., Farah, E., R. Hegde, S., Holcomb, C., Scott, D. J. & Sankaranarayanan, G., Apr 2024, In: Surgical endoscopy. 38, 4, p. 2219-2230 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Hiatal Hernia 100%
  • Fundoplication 99%
  • Herniorrhaphy 88%
  • Reproducibility of Results 69%
  • Virtual Reality 38%
• 2023

  A Comprehensive Analysis of Cerebellar Volumes in the 22q11.2 Deletion Syndrome

  Schmitt, J. E., DeBevits, J. J., Roalf, D. R., Ruparel, K., Gallagher, R. S., Gur, R. C., Alexander-Bloch, A., Eom, T. Y., Alam, S., Steinberg, J., Akers, W., Khairy, K., Crowley, T. B., Emanuel, B., Zakharenko, S. S., McDonald-McGinn, D. M. & Gur, R. E., Jan 2023, In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 8, 1, p. 79-90 12 p.

  Research output: Contribution to journal › Article › peer-review

  • DiGeorge Syndrome 100%
  • Cerebellum 24%
  • Frontal Lobe 17%
  • Psychotic Disorders 16%
  • Linear Models 14%
  5 Scopus citations

• Adapting to a Robotic Era: The Transferability of Open and Laparoscopic Skills to Robotic Surgery

  Farah, E., Abreu, A. A., Rail, B., Radi, I., Sankaranarayanan, G., Scott, D. J., Zeh, H. & Polanco, P. M., Dec 2023, In: Journal of Surgical Education. 80, 12, p. 1868-1876 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Robotics 100%
  • surgery 98%
  • Mandrillus 19%
  • resident 18%
  • Curriculum 15%

• Baseline performance in a robotic virtual reality platform predicts rate of skill acquisition in a proficiency-based curriculum: a cohort study of surgical trainees

  Abreu, A. A., Rail, B., Farah, E., Alterio, R. E., Scott, D. J., Sankaranarayanan, G., Zeh, H. J. & Polanco, P. M., Nov 2023, In: Surgical endoscopy. 37, 11, p. 8804-8809 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Virtual Reality 100%
  • Robotics 86%
  • Curriculum 80%
  • Internship and Residency 68%
  • Cohort Studies 56%
  1 Scopus citations

• Gold nanoparticle-enhanced X-ray microtomography of the rodent reveals region-specific cerebrospinal fluid circulation in the brain

  Pan, S., Yang, P. H., DeFreitas, D., Ramagiri, S., Bayguinov, P. O., Hacker, C. D., Snyder, A. Z., Wilborn, J., Huang, H., Koller, G. M., Raval, D. K., Halupnik, G. L., Sviben, S., Achilefu, S., Tang, R., Haller, G., Quirk, J. D., Fitzpatrick, J. A. J., Esakky, P. & Strahle, J. M., Dec 2023, In: Nature communications. 14, 1, 453.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • cerebrospinal fluid 100%
  • rodents 95%
  • X-Ray Microtomography 88%
  • Cord 83%
  • Gold 68%
  6 Scopus citations

• Objective metrics for hand-sewn bowel anastomoses can differentiate novice from expert surgeons

  Sankaranarayanan, G., Parker, L. M., Khan, A., Dials, J., Demirel, D., Halic, T., Crawford, A., Kruger, U., De, S. & Fleshman, J. W., Feb 2023, In: Surgical endoscopy. 37, 2, p. 1282-1292 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Least-Squares Analysis 100%
  • Hand 67%
  • Surgeons 63%
  • Colorectal Surgery 54%
  • Virtual Reality 54%
  1 Scopus citations

• Resting-state functional connectivity-based parcellation of the human dentate nucleus: new findings and clinical relevance

  Kulkarni, M., Kent, J. S., Park, K., Guell, X. & Anteraper, S., Sep 2023, In: Brain Structure and Function. 228, 7, p. 1799-1810 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Cerebellar Nuclei 100%
  • Signal-To-Noise Ratio 22%
  • Seeds 19%
  • Cerebellum 17%
  • Neuroimaging 17%
  1 Scopus citations

• The interactive medical simulation toolkit (iMSTK): an open source platform for surgical simulation

  Moore, J., Scheirich, H., Jadhav, S., Enquobahrie, A., Paniagua, B., Wilson, A., Bray, A., Sankaranarayanan, G. & Clipp, R. B., 2023, In: Frontiers in Virtual Reality. 4, 1130156.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Tissue 100%
  • Biopsy 76%
  • Surgery 59%
  • Hydrodynamics 50%
  • Visualization 45%
  1 Scopus citations

• What are essential laparoscopic skills these days? Results of the SAGES Fundamentals of Laparoscopic Surgery (FLS) Committee technical skills survey

  Seymour, N. E., Nepomnayshy, D., De, S., Banks, E., Breitkopf, D. M., Campagna, R., Gomez-Garibello, C., Green, I., Jacobsen, G., Korndorffer, J. R., Minasi, J., Okrainec, A., Matthew Ritter, E., Sankaranarayanan, G., Schwaitzberg, S., Soper, N. J., Vassiliou, M., Wagner, M. & Zevin, B., Oct 2023, In: Surgical endoscopy. 37, 10, p. 7676-7685 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Laparoscopy 100%
  • Surgeons 77%
  • Certification 21%
  • Laparoscopes 12%
  • Internship and Residency 9%
• 2022

  Ablation of VLA4 in multiple myeloma cells redirects tumor spread and prolongs survival

  Hathi, D., Chanswangphuwana, C., Cho, N., Fontana, F., Maji, D., Ritchey, J., O’Neal, J., Ghai, A., Duncan, K., Akers, W. J., Fiala, M., Vij, R., DiPersio, J. F., Rettig, M. & Shokeen, M., Dec 2022, In: Scientific reports. 12, 1, 30.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Multiple Myeloma 100%
  • Survival 56%
  • cyanine dye 5 52%
  • Neoplasms 32%
  • Bone Marrow Cells 31%
  12 Scopus citations

• Aconitate decarboxylase 1 is a mediator of polymicrobial sepsis

  Wu, R., Liu, J., Wang, N., Zeng, L., Yu, C., Chen, F., Wang, H., Billiar, T. R., Jiang, J., Tang, D. & Kang, R., Aug 24 2022, In: Science translational medicine. 14, 659, abo2028.

  Research output: Contribution to journal › Article › peer-review

  • aconitate decarboxylase 100%
  • Sepsis 37%
  • Cyclin-Dependent Kinase 2 28%
  • dinaciclib 12%
  • Innate Immunity 12%
  18 Scopus citations

• ALL-090 Highly Effective Combination of FLT3 and BCL2 Inhibitors in a Preclinical Model of Lineage Ambiguous Leukemia

  Montefiori, L., lacobucci, I., Budhraja, A., Moore, J., Baskin, R., DeVries, R., Backhaus, E., Johnson, M., Akers, W., Chepyala, D., Mehr, C., Seth, A., Mead, P., Opferman, J. & Mullighan, C., Oct 2022, In: Clinical Lymphoma, Myeloma and Leukemia. 22, p. S193-S194

  Research output: Contribution to journal › Article › peer-review

  • gilteritinib 100%
  • Leukemia 98%
  • venetoclax 79%
  • Animals 15%
  • Therapeutics 14%

• An End-To-End Pipeline for Fully Automatic Morphological Quantification of Mouse Brain Structures From MRI Imagery

  Alam, S., Eom, T. Y., Steinberg, J., Ackerman, D., Schmitt, J. E., Akers, W. J., Zakharenko, S. S. & Khairy, K., 2022, In: Frontiers in Bioinformatics. 2, 865443.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Magnetic Resonance Image 100%
  • Imagery 89%
  • Mouse 77%
  • Pipeline 70%
  • Quantification 67%
  1 Scopus citations

• An mTORC1 to HRI signaling axis promotes cytotoxicity of proteasome inhibitors in multiple myeloma

  Darawshi, O., Muz, B., Naamat, S. G., Praveen, B., Mahameed, M., Goldberg, K., Dipta, P., Shmuel, M., Forno, F., Boukeileh, S., Pahima, H., Hermann, J., Raab, M. S., Poos, A. M., Weinhold, N., Rosenbluh, C., Gatt, M. E., Palm, W., Azab, A. K. & Tirosh, B., Nov 2022, In: Cell Death and Disease. 13, 11, 969.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mechanistic Target of Rapamycin Complex 1 100%
  • Proteasome Inhibitors 95%
  • Multiple Myeloma 78%
  • In Vitro Techniques 6%
  • Hypoxia 5%
  3 Scopus citations

• Proton magnetic resonance spectroscopy detects cerebral metabolic derangement in a mouse model of brain coenzyme a deficiency

  Li, Y., Steinberg, J., Coleman, Z., Wang, S., Subramanian, C., Li, Y., Patay, Z., Akers, W., Rock, C. O., Jackowski, S. & Bagga, P., Dec 2022, In: Journal of Translational Medicine. 20, 1, 103.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 4-boronic acid benzophenone 86%
  • Coenzymes 79%
  • Coenzyme A 76%
  • Proton Magnetic Resonance Spectroscopy 72%
  • Coenzyme 66%
  3 Scopus citations
• 2021

  Detection of cold stress in plants using fluorescence lifetime imaging (Flim)

  Peng, O., Akers, W. & Berezin, M. Y., 2021, In: Current Analytical Chemistry. 17, 3, p. 317-327 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Fluorescence Lifetime 100%
  • High Throughput Screening 51%
  • Fluorescence Decay 27%
  • Fluorescence Intensity 21%
  • Leaf Like Crystal 20%
  3 Scopus citations

• Next-generation humanized patient-derived xenograft mouse model for pre-clinical antibody studies in neuroblastoma

  Nguyen, R., Patel, A. G., Griffiths, L. M., Dapper, J., Stewart, E. A., Houston, J., Johnson, M., Akers, W. J., Furman, W. L. & Dyer, M. A., Mar 2021, In: Cancer Immunology, Immunotherapy. 70, 3, p. 721-732 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neuroblastoma 100%
  • Heterografts 90%
  • Natural Killer Cells 77%
  • Clinical Studies 69%
  • Antibodies 55%
  16 Scopus citations

• Targeting the spliceosome through RBM39 degradation results in exceptional responses in high-risk neuroblastoma models

  Singh, S., Quarni, W., Goralski, M., Wan, S., Jin, H., van de Velde, L. A., Fang, J., Wu, Q., Abu-Zaid, A., Wang, T., Singh, R., Craft, D., Fan, Y., Confer, T., Johnson, M., Akers, W. J., Wang, R., Murray, P. J., Thomas, P. G., Nijhawan, D., & 2 othersDavidoff, A. M. & Yang, J., Nov 2021, In: Science Advances. 7, 47, eabj5405.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • N-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide 100%
  • Spliceosomes 92%
  • Neuroblastoma 67%
  • RNA Splicing Factors 22%
  • Ubiquitin-Protein Ligases 19%
  24 Scopus citations
• 2020

  Spectrum of Posttransplant Lymphoproliferations in NSG Mice and Their Association With EBV Infection After Engraftment of Pediatric Solid Tumors

  Tillman, H., Vogel, P., Rogers, T., Akers, W. & Rehg, J. E., May 1 2020, In: Veterinary pathology. 57, 3, p. 445-456 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Human gammaherpesvirus 4 100%
  • pediatrics 94%
  • Epstein-Barr Virus Infections 89%
  • neoplasms 57%
  • Pediatrics 47%
  9 Scopus citations
• 2019

  Interleukin-15 enhances anti-GD2 antibody-mediated cytotoxicity in an orthotopic PDX model of neuroblastoma

  Nguyen, R., Moustaki, A., Norrie, J. L., Brown, S., Akers, W. J., Shirinifard, A. & Dyer, M. A., Dec 15 2019, In: Clinical Cancer Research. 25, 24, p. 7554-7564 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Interleukin-15 100%
  • Neuroblastoma 78%
  • Heterografts 70%
  • Interleukin-2 70%
  • Anti-Idiotypic Antibodies 66%
  32 Scopus citations
• 2018

  Preclinical development of CD38-Targeted [ ⁸⁹ Zr]Zr-DFO-Daratumumab for Imaging Multiple Myeloma

  Ghai, A., Maji, D., Cho, N., Chanswangphuwana, C., Rettig, M., Shen, D., DiPersio, J., Akers, W., Dehdashti, F., Achilefu, S., Vij, R. & Shokeen, M., Feb 1 2018, In: Journal of Nuclear Medicine. 59, 2, p. 216-222 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • daratumumab 100%
  • Deferoxamine 73%
  • Multiple Myeloma 58%
  • Luciferases 7%
  • benzyl isothiocyanate 6%
  47 Scopus citations
• 2016

  Detection of 18F-FDG PET/CT occult lesions with 18F-DCFPyL PET/CT in a patient with metastatic renal cell carcinoma

  Rowe, S. P., Gorin, M. A., Hammers, H. J., Pomper, M. G., Allaf, M. E. & Javadi, M. S., Jan 1 2016, In: Clinical nuclear medicine. 41, 1, p. 83-85 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acid 100%
  • Fluorodeoxyglucose F18 53%
  • Renal Cell Carcinoma 48%
  • Clear-cell metastatic renal cell carcinoma 27%
  • Prostate-Specific Antigen 17%
  47 Scopus citations
• 2015

  Imaging of metastatic clear cell renal cell carcinoma with PSMA-targeted ¹⁸F-DCFPyL PET/CT

  Rowe, S. P., Gorin, M. A., Hammers, H. J., Som Javadi, M., Hawasli, H., Szabo, Z., Cho, S. Y., Pomper, M. G. & Allaf, M. E., Dec 1 2015, In: Annals of Nuclear Medicine. 29, 10, p. 877-882 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acid 100%
  • Clear-cell metastatic renal cell carcinoma 81%
  • Renal Cell Carcinoma 48%
  • Positron-Emission Tomography 46%
  • Molecular Imaging 9%
  143 Scopus citations
• 2005

  Routine clinical brain MRI sequences for use at 3.0 tesla

  Lu, H., Nagae-Poetscher, L. M., Golay, X., Lin, D., Pomper, M. & Van Zijl, P. C. M., Jul 2005, In: Journal of Magnetic Resonance Imaging. 22, 1, p. 13-22 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Brain 100%
  • Noise 93%
  • Signal-To-Noise Ratio 58%
  • Gray Matter 51%
  • White Matter 46%
  256 Scopus citations