Thomas J Wang

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Pattaro, C., Teumer, A., Gorski, M., Chu, A. Y., Li, M., Mijatovic, V., Garnaas, M., Tin, A., Sorice, R., Li, Y., Taliun, D., Olden, M., Foster, M., Yang, Q., Chen, M. H., Pers, T. H., Johnson, A. D., Ko, Y. A., Fuchsberger, C., Tayo, B., & 678 othersNalls, M., Feitosa, M. F., Isaacs, A., Dehghan, A., D'Adamo, P., Adeyemo, A., Dieffenbach, A. K., Zonderman, A. B., Nolte, I. M., Van Der Most, P. J., Wright, A. F., Shuldiner, A. R., Morrison, A. C., Hofman, A., Smith, A. V., Dreisbach, A. W., Franke, A., Uitterlinden, A. G., Metspalu, A., Tonjes, A., Lupo, A., Robino, A., Johansson, Å., Demirkan, A., Kollerits, B., Freedman, B. I., Ponte, B., Oostra, B. A., Paulweber, B., Krämer, B. K., Mitchell, B. D., Buckley, B. M., Peralta, C. A., Hayward, C., Helmer, C., Rotimi, C. N., Shaffer, C. M., Müller, C., Sala, C., Van Duijn, C. M., Saint-Pierre, A., Ackermann, D., Shriner, D., Ruggiero, D., Toniolo, D., Lu, Y., Cusi, D., Czamara, D., Ellinghaus, D., Siscovick, D. S., Ruderfer, D., Gieger, C., Grallert, H., Rochtchina, E., Atkinson, E. J., Holliday, E. G., Boerwinkle, E., Salvi, E., Bottinger, E. P., Murgia, F., Rivadeneira, F., Ernst, F., Kronenberg, F., Hu, F. B., Navis, G. J., Curhan, G. C., Ehret, G. B., Homuth, G., Coassin, S., Thun, G. A., Pistis, G., Gambaro, G., Malerba, G., Montgomery, G. W., Eiriksdottir, G., Jacobs, G., Li, G., Wichmann, H. E., Campbell, H., Schmidt, H., Wallaschofski, H., Völzke, H., Brenner, H., Kroemer, H. K., Kramer, H., Lin, H., Leach, I. M., Ford, I., Guessous, I., Rudan, I., Prokopenko, I., Borecki, I., Heid, I. M., Kolcic, I., Persico, I., Jukema, J. W., Wilson, J. F., Felix, J. F., Divers, J., Lambert, J. C., Stafford, J. M., Gaspoz, J. M., Smith, J. A., Faul, J. D., Wang, J. J., Ding, J., Hirschhorn, J. N., Attia, J., Whitfield, J. B., Chalmers, J., Viikari, J., Coresh, J., Denny, J. C., Karjalainen, J., Fernandes, J. K., Endlich, K., Butterbach, K., Keene, K. L., Lohman, K., Portas, L., Launer, L. J., Lyytikäinen, L. P., Yengo, L., Franke, L., Ferrucci, L., Rose, L. M., Kedenko, L., Rao, M., Struchalin, M., Kleber, M. E., Cavalieri, M., Haun, M., Cornelis, M. C., Ciullo, M., Pirastu, M., De Andrade, M., McEvoy, M. A., Woodward, M., Adam, M., Cocca, M., Nauck, M., Imboden, M., Waldenberger, M., Pruijm, M., Metzger, M., Stumvoll, M., Evans, M. K., Sale, M. M., Kähönen, M., Boban, M., Bochud, M., Rheinberger, M., Verweij, N., Bouatia-Naji, N., Martin, N. G., Hastie, N., Probst-Hensch, N., Soranzo, N., Devuyst, O., Raitakari, O., Gottesman, O., Franco, O. H., Polasek, O., Gasparini, P., Munroe, P. B., Ridker, P. M., Mitchell, P., Muntner, P., Meisinger, C., Smit, J. H., Abecasis, G. R., Adair, L. S., Alexander, M., Altshuler, D., Amin, N., Arking, D. E., Arora, P., Aulchenko, Y., Bakker, S. J. L., Bandinelli, S., Barroso, I., Beckmann, J. S., Beilby, J. P., Bergman, R. N., Bergmann, S., Bis, J. C., Boehnke, M., Bonnycastle, L. L., Bornstein, S. R., Bots, M. L., Bragg-Gresham, J. L., Brand, S. M., Brand, E., Braund, P. S., Brown, M. J., Burton, P. R., Casas, J. P., Caulfield, M. J., Chakravarti, A., Chambers, J. C., Chandak, G. R., Chang, Y. P. C., Charchar, F. J., Chaturvedi, N., Cho, Y. S., Clarke, R., Collins, F. S., Collins, R., Connell, J. M., Cooper, J. A., Cooper, M. N., Cooper, R. S., Corsi, A. M., Dörr, M., Dahgam, S., Danesh, J., Smith, G. D., Day, I. N. M., Deloukas, P., Denniff, M., Dominiczak, A. F., Dong, Y., Doumatey, A., Elliott, P., Elosua, R., Erdmann, J., Eyheramendy, S., Farrall, M., Fava, C., Forrester, T., Fowkes, F. G. R., Fox, E. R., Frayling, T. M., Galan, P., Ganesh, S. K., Garcia, M., Gaunt, T. R., Glazer, N. L., Go, M. J., Goel, A., Grässler, J., Grobbee, D. E., Groop, L., Guarrera, S., Guo, X., Hadley, D., Hamsten, A., Han, B. G., Hardy, R., Hartikainen, A. L., Heath, S., Heckbert, S. R., Hedblad, B., Hercberg, S., Hernandez, D., Hicks, A. A., Hilton, G., Hingorani, A. D., Hoffman Bolton, J. A., Hopewell, J. C., Howard, P., Humphries, S. E., Hunt, S. C., Hveem, K., Ikram, M. A., Islam, M., Iwai, N., Jarvelin, M. R., Jackson, A. U., Jafar, T. H., Janipalli, C. S., Johnson, T., Kathiresan, S., Khaw, K. T., Kim, H. L., Kinra, S., Kita, Y., Kivimaki, M., Kooner, J. S., Kumar, M. J. K., Kuh, D., Kulkarni, S. R., Kumari, M., Kuusisto, J., Kuznetsova, T., Laakso, M., Laan, M., Laitinen, J., Lakatta, E. G., Langefeld, C. D., Larson, M. G., Lathrop, M., Lawlor, D. A., Lawrence, R. W., Lee, J. Y., Lee, N. R., Levy, D., Li, Y., Longstreth, W. T., Luan, J., Lucas, G., Ludwig, B., Mangino, M., Mani, K. R., Marmot, M. G., Mattace-Raso, F. U. S., Matullo, G., McArdle, W. L., McKenzie, C. A., Meitinger, T., Melander, O., Meneton, P., Meschia, J. F., Miki, T., Milaneschi, Y., Mohlke, K. L., Mooser, V., Morken, M. A., Morris, R. W., Mosley, T. H., Najjar, S., Narisu, N., Newton-Cheh, C., Nguyen, K. D. H., Nilsson, P., Nyberg, F., O'Donnell, C. J., Ogihara, T., Ohkubo, T., Okamura, T., Ong, R. T. H., Ongen, H., Onland-Moret, N. C., O'Reilly, P. F., Org, E., Orru, M., Palmas, W., Palmen, J., Palmer, L. J., Palmer, N. D., Parker, A. N., Peden, J. F., Peltonen, L., Perola, M., Pihur, V., Platou, C. G. P., Plump, A., Prabhakaran, D., Psaty, B. M., Raffel, L. J., Rao, D. C., Rasheed, A., Ricceri, F., Rice, K. M., Rosengren, A., Rotter, J. I., Rudock, M. E., Sõber, S., Salako, T., Saleheen, D., Salomaa, V., Samani, N. J., Schwartz, S. M., Schwarz, P. E. H., Scott, L. J., Scott, J., Scuteri, A., Sehmi, J. S., Seielstad, M., Seshadri, S., Sharma, P., Shaw-Hawkins, S., Shi, G., Shrine, N. R. G., Sijbrands, E. J. G., Sim, X., Singleton, A., Sjögren, M., Smith, N. L., Artigas, M. S., Spector, T. D., Staessen, J. A., Stancakova, A., Steinle, N. I., Strachan, D. P., Stringham, H. M., Sun, Y. V., Swift, A. J., Tabara, Y., Tai, E. S., Talmud, P. J., Taylor, A., Terzic, J., Thelle, D. S., Tobin, M. D., Tomaszewski, M., Tripathy, V., Tuomilehto, J., Tzoulaki, I., Uda, M., Ueshima, H., Uiterwaal, C. S. P. M., Umemura, S., Van Der Harst, P., Van Der Schouw, Y. T., Van Gilst, W. H., Vartiainen, E., Vasan, R. S., Veldre, G., Verwoert, G. C., Viigimaa, M., Vinay, D. G., Vineis, P., Voight, B. F., Vollenweider, P., Wagenknecht, L. E., Wain, L. V., Wang, X., Wang, T. J., Wareham, N. J., Watkins, H., Weder, A. B., Whincup, P. H., Wiggins, K. L., Witteman, J. C. M., Wong, A., Wu, Y., Yajnik, C. S., Yao, J., Young, J. H., Zelenika, D., Zhai, G., Zhang, W., Zhang, F., Zhao, J. H., Zhu, H., Zhu, X., Zitting, P., Zukowska-Szczechowska, E., Okada, Y., Wu, J. Y., Gu, D., Takeuchi, F., Takahashi, A., Maeda, S., Tsunoda, T., Chen, P., Lim, S. C., Wong, T. Y., Liu, J., Young, T. L., Aung, T., Teo, Y. Y., Kim, Y. J., Kang, D., Chen, C. H., Tsai, F. J., Chang, L. C., Fann, S. J. C., Mei, H., Hixson, J. E., Chen, S., Katsuya, T., Isono, M., Albrecht, E., Yamamoto, K., Kubo, M., Nakamura, Y., Kamatani, N., Kato, N., He, J., Chen, Y. T., Tanaka, T., Reilly, M. P., Schunkert, H., Assimes, T. L., Hall, A., Hengstenberg, C., König, I. R., Laaksonen, R., McPherson, R., Thompson, J. R., Thorsteinsdottir, U., Ziegler, A., Absher, D., Chen, L., Cupples, L. A., Halperin, E., Li, M., Musunuru, K., Preuss, M., Schillert, A., Thorleifsson, G., Wells, G. A., Holm, H., Roberts, R., Stewart, A. F. R., Fortmann, S., Go, A., Hlatky, M., Iribarren, C., Knowles, J., Myers, R., Quertermous, T., Sidney, S., Risch, N., Tang, H., Blankenberg, S., Schnabel, R., Sinning, C., Lackner, K. J., Tiret, L., Nicaud, V., Cambien, F., Bickel, C., Rupprecht, H. J., Perret, C., Proust, C., Münzel, T. F., Barbalic, M., Chen, I. Y. D., Demissie-Banjaw, S., Folsom, A., Lumley, T., Marciante, K., Taylor, K. D., Volcik, K., Gretarsdottir, S., Gulcher, J. R., Kong, A., Stefansson, K., Thorgeirsson, G., Andersen, K., Fischer, M., Grosshennig, A., Linsel-Nitschke, P., Stark, K., Schreiber, S., Aherrahrou, Z., Bruse, P., Doering, A., Klopp, N., Diemert, P., Loley, C., Medack, A., Nahrstedt, J., Peters, A., Wagner, A. K., Willenborg, C., Böhm, B. O., Dobnig, H., Grammer, T. B., Hoffmann, M. M., Meinitzer, A., Winkelmann, B. R., Pilz, S., Renner, W., Scharnagl, H., Stojakovic, T., Tomaschitz, A., Winkler, K., Guiducci, C., Burtt, N., Gabriel, S. B., Dandona, S., Jarinova, O., Qu, L., Wilensky, R., Matthai, W., Hakonarson, H. H., Devaney, J., Burnett, M. S., Pichard, A. D., Kent, K. M., Satler, L., Lindsay, J. M., Waksman, R., Knouff, C. W., Waterworth, D. M., Walker, M. C., Epstein, S. E., Rader, D. J., Nelson, C. P., Wright, B. J., Balmforth, A. J., Ball, S. G., Loehr, L. R., Rosamond, W. D., Benjamin, E., Haritunians, T., Couper, D., Murabito, J., Wang, Y. A., Stricker, B. H., Chang, P. P., Willerson, J. T., Felix, S. B., Watzinger, N., Aragam, J., Zweiker, R., Lind, L., Rodeheffer, R. J., Greiser, K. H., Deckers, J. W., Stritzke, J., Ingelsson, E., Kullo, I., Haerting, J., Reffelmann, T., Redfield, M. M., Werdan, K., Mitchell, G. F., Arnett, D. K., Gottdiener, J. S., Blettner, M., Friedrich, N., Kovacs, P., Wild, P. S., Froguel, P., Rettig, R., Mägi, R., Biffar, R., Schmidt, R., Middelberg, R. P. S., Carroll, R. J., Penninx, B. W., Scott, R. J., Katz, R., Sedaghat, S., Wild, S. H., Kardia, S. L. R., Ulivi, S., Hwang, S. J., Enroth, S., Kloiber, S., Trompet, S., Stengel, B., Hancock, S. J., Turner, S. T., Rosas, S. E., Stracke, S., Harris, T. B., Zeller, T., Zemunik, T., Lehtimäki, T., Illig, T., Aspelund, T., Nikopensius, T., Esko, T., Tanaka, T., Gyllensten, U., Völker, U., Emilsson, V., Vitart, V., Aalto, V., Gudnason, V., Chouraki, V., Chen, W. M., Igl, W., März, W., Koenig, W., Lieb, W., Loos, R. J. F., Liu, Y., Snieder, H., Pramstaller, P. P., Parsa, A., O'Connell, J. R., Susztak, K., Hamet, P., Tremblay, J., De Boer, I. H., Böger, C. A., Goessling, W., Chasman, D. I., Köttgen, A., Kao, W. H. L. & Fox, C. S., Jan 21 2016, In: Nature communications. 7, 10023.

Research output: Contribution to journal › Article › peer-review

Open Access

361 Scopus citations

Genetic architecture of the cardiovascular risk proteome

Benson, M. D., Yang, Q., Ngo, D., Zhu, Y., Shen, D., Farrell, L. A., Sinha, S., Keyes, M. J., Vasan, R. S., Larson, M. G., Smith, J. G., Wang, T. J. & Gerszten, R. E., 2018, In: Circulation. 137, 11, p. 1158-1172 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

55 Scopus citations

Genetic Architecture of Plasma Alpha-Aminoadipic Acid Reveals a Relationship With High-Density Lipoprotein Cholesterol

Shi, M., Wang, C., Mei, H., Temprosa, M., Florez, J. C., Tripputi, M., Merino, J., Lipworth, L., Shu, X. O., Gerszten, R. E., Wang, T. J., Beckman, J. A., Gamboa, J. L., Mosley, J. D. & Ferguson, J. F., Jun 7 2022, In: Journal of the American Heart Association. 11, 11, e024388.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Genetic and clinical correlates of early-outgrowth colony-forming units

Shaw, S. Y., Cheng, S., Cupples, L. A., Larson, M. G., McCabe, E. L., Ngwa, J. S., Wang, Y. A., Martin, R. P., Klein, R. J., Hashmi, B., Ajijola, O. A., Lau, E., O'Donnell, C. J., Vasan, R. S., Cohen, K. S. & Wang, T. J., Jun 2011, In: Circulation: Cardiovascular Genetics. 4, 3, p. 296-304 9 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Gastrointestinal synthetic epithelial linings

Li, J., Wang, T., Kirtane, A. R., Shi, Y., Jones, A., Moussa, Z., Lopes, A., Collins, J., Tamang, S. M., Hess, K., Shakur, R., Karandikar, P., Lee, J. S., Huang, H. W., Hayward, A. & Traverso, G., Aug 2020, In: Science translational medicine. 12, 558, EABC0441.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Gamma glutamyl transferase and metabolic syndrome, cardiovascular disease, and mortality risk: The Framingham Heart Study

Lee, D. S., Evans, J. C., Robins, S. J., Wilson, P. W., Albano, I., Fox, C. S., Wang, T. J., Benjamin, E. J., D'Agostino, R. B. & Vasan, R. S., Jan 2007, In: Arteriosclerosis, thrombosis, and vascular biology. 27, 1, p. 127-133 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

455 Scopus citations

Galectin-3 Inhibition With Modified Citrus Pectin in Hypertension

Lau, E. S., Liu, E., Paniagua, S. M., Sarma, A. A., Zampierollo, G., López, B., Díez, J., Wang, T. J. & Ho, J. E., Jan 2021, In: JACC: Basic to Translational Science. 6, 1, p. 12-21 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Framingham Heart Study 100K Project: Genome-wide associations for blood pressure and arterial stiffness

Levy, D., Larson, M. G., Benjamin, E. J., Newton-Cheh, C., Wang, T. J., Hwang, S. J., Vasan, R. S. & Mitchell, G. F., 2007, In: BMC Medical Genetics. 8, SUPPL. 1, S3.

Research output: Contribution to journal › Article › peer-review

Open Access

227 Scopus citations

Framingham Heart Study 100K project: Genome-wide associations for cardiovascular disease outcomes

Larson, M. G., Atwood, L. D., Benjamin, E. J., Cupples, L. A., D'Agostino, R. B., Fox, C. S., Govindaraju, D. R., Guo, C. Y., Heard-Costa, N. L., Hwang, S. J., Murabito, J. M., Newton-Cheh, C., O'Donnell, C. J., Seshadri, S., Vasan, R. S., Wang, T. J., Wolf, P. A. & Levy, D., 2007, In: BMC Medical Genetics. 8, SUPPL. 1, S5.

Research output: Contribution to journal › Article › peer-review

Open Access

162 Scopus citations

Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease

Gutiérrez, O. M., Januzzi, J. L., Isakova, T., Laliberte, K., Smith, K., Collerone, G., Sarwar, A., Hoffmann, U., Coglianese, E., Christenson, R., Wang, T. J., DeFilippi, C. & Wolf, M., May 19 2009, In: Circulation. 119, 19, p. 2545-2552 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

715 Scopus citations

Feasibility and Short-Term Effects of a Multi-Component Emergency Department Blood Pressure Intervention: A Pilot Randomized Trial

Spieker, A. J., Nelson, L. A., Rothman, R. L., Roumie, C. L., Kripalani, S., Coco, J., Fabbri, D., Levy, P., Collins, S. P., Wang, T., Liu, D. & McNaughton, C. D., Mar 1 2022, In: Journal of the American Heart Association. 11, 5, e024339.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Exercise Blood Pressure and the Risk of Incident Cardiovascular Disease (from the Framingham Heart Study)

Lewis, G. D., Gona, P., Larson, M. G., Plehn, J. F., Benjamin, E. J., O'Donnell, C. J., Levy, D., Vasan, R. S. & Wang, T. J., Jun 1 2008, In: American Journal of Cardiology. 101, 11, p. 1614-1620 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

93 Scopus citations

Endogenous sex hormones and cardiovascular disease incidence in men

Ärnlöv, J., Pencina, M. J., Amin, S., Nam, B. H., Benjamin, E. J., Murabito, J. M., Wang, T. J., Knapp, P. E., D'Agostino, R. B., Bhasin, S. & Vasan, R. S., Aug 1 2006, In: Annals of internal medicine. 145, 3, p. 176-184 9 p.

Research output: Contribution to journal › Article › peer-review

183 Scopus citations

Emergency Department Management of Patients With Febrile Neutropenia: Guideline Concordant or Overly Aggressive?

Baugh, C. W., Wang, T. J., Caterino, J. M., Baker, O. N., Brooks, G. A., Reust, A. C. & Pallin, D. J., Jan 1 2017, In: Academic Emergency Medicine. 24, 1, p. 83-91 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development

Mayers, J. R., Wu, C., Clish, C. B., Kraft, P., Torrence, M. E., Fiske, B. P., Yuan, C., Bao, Y., Townsend, M. K., Tworoger, S. S., Davidson, S. M., Papagiannakopoulos, T., Yang, A., Dayton, T. L., Ogino, S., Stampfer, M. J., Giovannucci, E. L., Qian, Z. R., Rubinson, D. A., Ma, J., & 15 othersSesso, H. D., Gaziano, J. M., Cochrane, B. B., Liu, S., Wactawski-Wende, J., Manson, J. E., Pollak, M. N., Kimmelman, A. C., Souza, A., Pierce, K., Wang, T. J., Gerszten, R. E., Fuchs, C. S., Vander Heiden, M. G. & Wolpin, B. M., Oct 1 2014, In: Nature medicine. 20, 10, p. 1193-1198 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

486 Scopus citations

Electrocardiographic QRS duration and the risk of congestive heart failure: The Framingham heart study

Dhingra, R., Pencina, M. J., Wang, T. J., Nam, B. H., Benjamin, E. J., Levy, D., Larson, M. G., Kannel, W. B., D'Agostino, R. B. & Vasan, R. S., May 2006, In: Hypertension. 47, 5, p. 861-867 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

99 Scopus citations

Effects of vitamin d supplementation on cardiovascular and glycemic biomarkers

Miao, J., Bachmann, K. N., Huang, S., Su, Y. R., Dusek, J., Newton-Cheh, C., Arora, P. & Wang, T. J., 2021, In: Journal of the American Heart Association. 10, 10, e017727.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Effects of transdermal testosterone on natriuretic peptide levels in women: A randomized placebo-controlled pilot study

Lin, E., McCabe, E., Newton-Cheh, C., Bloch, K., Buys, E., Wang, T. & Miller, K. K., Feb 2012, In: Fertility and sterility. 97, 2, p. 489-493 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Effects of subacute dietary salt intake and acute volume expansion on diastolic function in young normotensive individuals

Mak, G. S., Sawaya, H., Khan, A. M., Arora, P., Martinez, A., Ryan, A., Ernande, L., Newton-Cheh, C., Wang, T. J. & Scherrer-Crosbie, M., Nov 2013, In: European heart journal cardiovascular Imaging. 14, 11, p. 1092-1098 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Effects of oral contraceptives on natriuretic peptide levels in women with hypothalamic amenorrhea: A pilot study

Lin, E., Grinspoon, S., Wang, T. & Miller, K. K., Jun 30 2011, In: Fertility and sterility. 95, 8, p. 2605-2607 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Effect of weight loss after weight loss surgery on plasma N-terminal pro-B-type natriuretic peptide levels

Chen-Tournoux, A., Khan, A. M., Baggish, A. L., Castro, V. M., Semigran, M. J., McCabe, E. L., Moukarbel, G., Reingold, J., Durrani, S., Lewis, G. D., Newton-Cheh, C., Scherrer-Crosbie, M., Kaplan, L. M. & Wang, T. J., Nov 15 2010, In: American Journal of Cardiology. 106, 10, p. 1450-1455 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

52 Scopus citations

Effect of Testosterone on Natriuretic Peptide Levels

Bachmann, K. N., Huang, S., Lee, H., Dichtel, L. E., Gupta, D. K., Burnett, J. C., Miller, K. K., Wang, T. J. & Finkelstein, J. S., Mar 26 2019, In: Journal of the American College of Cardiology. 73, 11, p. 1288-1296 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

Effect of phosphodiesterase inhibition on insulin resistance in obese individuals

Ho, J. E., Arora, P., Walford, G. A., Ghorbani, A., Guanaga, D. P., Dhakal, B. P., Nathan, D. I., Buys, E. S., Florez, J. C., Newton-Cheh, C., Lewis, G. D. & Wang, T. J., 2014, In: Journal of the American Heart Association. 3, 5, e001001.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Effect of Dietary Sodium on Blood Pressure: A Crossover Trial

Gupta, D. K., Lewis, C. E., Varady, K. A., Su, Y. R., Madhur, M. S., Lackland, D. T., Reis, J. P., Wang, T. J., Lloyd-Jones, D. M. & Allen, N. B., Dec 19 2023, In: JAMA. 330, 23, p. 2258-2266 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Effect of 2022 ACC/AHA/HFSA Criteria on Stages of Heart Failure in a Pooled Community Cohort

Mohebi, R., Wang, D., Lau, E. S., Parekh, J. K., Allen, N., Psaty, B. M., Benjamin, E. J., Levy, D., Wang, T. J., Shah, S. J., Gottdiener, J. S., Januzzi, J. L. & Ho, J. E., Jun 13 2023, In: Journal of the American College of Cardiology. 81, 23, p. 2231-2242 12 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Early repolarization pattern in competitive athletes: Clinical correlates and the effects of exercise training

Noseworthy, P. A., Weiner, R., Kim, J., Keelara, V., Wang, F., Berkstresser, B., Wood, M. J., Wang, T. J., Picard, M. H., Hutter, A. M., Newton-Cheh, C. & Baggish, A. L., Aug 2011, In: Circulation: Arrhythmia and Electrophysiology. 4, 4, p. 432-440 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

125 Scopus citations

Dynamic regulation of circulating microRNA during acute exhaustive exercise and sustained aerobic exercise training

Baggish, A. L., Hale, A., Weiner, R. B., Lewis, G. D., Systrom, D., Wang, F., Wang, T. J. & Chan, S. Y., Aug 2011, In: Journal of Physiology. 589, 16, p. 3983-3994 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

347 Scopus citations

Distribution and clinical correlates of the interleukin receptor family member soluble ST2 in the Framingham Heart Study

Coglianese, E. E., Larson, M. G., Vasan, R. S., Ho, J. E., Ghorbani, A., McCabe, E. L., Cheng, S., Fradley, M. G., Kretschman, D., Gao, W., O'Connor, G., Wang, T. J. & Januzzi, J. L., Dec 2012, In: Clinical chemistry. 58, 12, p. 1673-1681 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

160 Scopus citations

Distinct metabolomic signatures are associated with longevity in humans

Cheng, S., Larson, M. G., McCabe, E. L., Murabito, J. M., Rhee, E. P., Ho, J. E., Jacques, P. F., Ghorbani, A., Magnusson, M., Souza, A. L., Deik, A. A., Pierce, K. A., Bullock, K., O'Donnell, C. J., Melander, O., Clish, C. B., Vasan, R. S., Gerszten, R. E. & Wang, T. J., Apr 13 2015, In: Nature communications. 6, 6791.

Research output: Contribution to journal › Article › peer-review

Open Access

117 Scopus citations

Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes

O’Sullivan, J. F., Morningstar, J. E., Yang, Q., Zheng, B., Gao, Y., Jeanfavre, S., Scott, J., Fernandez, C., Zheng, H., O’Connor, S., Cohen, P., Vasan, R. S., Long, M. T., Wilson, J. G., Melander, O., Wang, T. J., Fox, C., Peterson, R. T., Clish, C. B., Corey, K. E., & 1 othersGerszten, R. E., Dec 1 2017, In: Journal of Clinical Investigation. 127, 12, p. 4394-4402 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

104 Scopus citations

Dimethylglycine deficiency and the development of diabetes

Magnusson, M., Wang, T. J., Clish, C., Engström, G., Nilsson, P., Gerszten, R. E. & Melander, O., Aug 2015, In: Diabetes. 64, 8, p. 3010-3016 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

50 Scopus citations

Differences in Natriuretic Peptide Levels by Race/Ethnicity (From the Multi-Ethnic Study of Atherosclerosis)

Gupta, D. K., Daniels, L. B., Cheng, S., deFilippi, C. R., Criqui, M. H., Maisel, A. S., Lima, J. A., Bahrami, H., Greenland, P., Cushman, M., Tracy, R., Siscovick, D., Bertoni, A. G., Cannone, V., Burnett, J. C., Carr, J. J. & Wang, T. J., Sep 15 2017, In: American Journal of Cardiology. 120, 6, p. 1008-1015 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

48 Scopus citations

Dietary sodium restriction decreases insulin secretion without affecting insulin sensitivity in humans

Luther, J. M., Byrne, L. M., Yu, C., Wang, T. J. & Brown, N. J., Oct 1 2014, In: Journal of Clinical Endocrinology and Metabolism. 99, 10, p. E1895-E1902

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study

Schnabel, R. B., Sullivan, L. M., Levy, D., Pencina, M. J., Massaro, J. M., D'Agostino, R. B., Newton-Cheh, C., Yamamoto, J. F., Magnani, J. W., Tadros, T. M., Kannel, W. B., Wang, T. J., Ellinor, P. T., Wolf, P. A., Vasan, R. S. & Benjamin, E. J., 2009, In: The Lancet. 373, 9665, p. 739-745 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

842 Scopus citations

Development and validation of optimal phenomapping methods to estimate long-term atherosclerotic cardiovascular disease risk in patients with type 2 diabetes

Segar, M. W., Patel, K. V., Vaduganathan, M., Caughey, M. C., Jaeger, B. C., Basit, M., Willett, D., Butler, J., Sengupta, P. P., Wang, T. J., McGuire, D. K. & Pandey, A., Jul 2021, In: Diabetologia. 64, 7, p. 1583-1594 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Depressive Symptoms and Incident Heart Failure Risk in the Southern Community Cohort Study

Dixon, D. D., Xu, M., Akwo, E. A., Nair, D., Schlundt, D., Wang, T. J., Blot, W. J., Lipworth, L. & Gupta, D. K., Apr 2022, In: JACC: Heart Failure. 10, 4, p. 254-262 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Cross-sectional relations of multiple biomarkers representing distinct biological pathways to plasma markers of collagen metabolism in the community

Joseph, J., Pencina, M. J., Wang, T. J., Hayes, L., Tofler, G. H., Jacques, P., Selhub, J., Levy, D., D'Agostino, R. B., Benjamin, E. J. & Vasan, R. S., Jun 2009, In: Journal of hypertension. 27, 6, p. 1317-1324 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Cross-sectional relations of multiple biomarkers from distinct biological pathways to brachial artery endothelial function

Kathiresan, S., Gona, P., Larson, M. G., Vita, J. A., Mitchell, G. F., Tofler, G. H., Levy, D., Newton-Cheh, C., Wang, T. J., Benjamin, E. J. & Vasan, R. S., Feb 2006, In: Circulation. 113, 7, p. 938-945 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

82 Scopus citations

Cross-sectional relations of electrocardiographic QRS duration to left ventricular dimensions: The Framingham Heart Study

Dhingra, R., Ho Nam, B., Benjamin, E. J., Wang, T. J., Larson, M. G., D'Agostino, R. B., Levy, D. & Vasan, R. S., Mar 1 2005, In: Journal of the American College of Cardiology. 45, 5, p. 685-689 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

88 Scopus citations

Cross-classification of microalbuminuria and reduced glomerular filtration rate: Associations between cardiovascular disease risk factors and clinical outcomes

Foster, M. C., Hwang, S. J., Larson, M. G., Parikh, N. I., Meigs, J. B., Vasan, R. S., Wang, T. J., Levy, D. & Fox, C. S., Jul 9 2007, In: Archives of Internal Medicine. 167, 13, p. 1386-1392 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

118 Scopus citations

C-reactive protein is associated with subclinical epicardial coronary calcification in men and women: The Framingham Heart Study

Wang, T. J., Larson, M. G., Levy, D., Benjamin, E. J., Kupka, M. J., Manning, W. J., Clouse, M. E., D'Agostino, R. B., Wilson, P. W. F. & O'Donnell, C. J., Sep 3 2002, In: Circulation. 106, 10, p. 1189-1191 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

166 Scopus citations

Correlation of renin angiotensin and aldosterone system activity with subcutaneous and visceral adiposity: The framingham heart study

O'Seaghdha, C. M., Hwang, S. J., Vasan, R. S., Larson, M. G., Hoffmann, U., Wang, T. J. & Fox, C. S., Apr 4 2012, In: BMC Endocrine Disorders. 12, 3.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Common variants in KCNN3 are associated with lone atrial fibrillation

Ellinor, P. T., Lunetta, K. L., Glazer, N. L., Pfeufer, A., Alonso, A., Chung, M. K., Sinner, M. F., De Bakker, P. I. W., Mueller, M., Lubitz, S. A., Fox, E., Darbar, D., Smith, N. L., Smith, J. D., Schnabel, R. B., Soliman, E. Z., Rice, K. M., Van Wagoner, D. R., Beckmann, B. M., Van Noord, C., & 42 othersWang, K., Ehret, G. B., Rotter, J. I., Hazen, S. L., Steinbeck, G., Smith, A. V., Launer, L. J., Harris, T. B., Makino, S., Nelis, M., Milan, D. J., Perz, S., Esko, T., Köttgen, A., Moebus, S., Newton-Cheh, C., Li, M., Möhlenkamp, S., Wang, T. J., Linda Kao, W. H., Vasan, R. S., Nöthen, M. M., MacRae, C. A., Ch Stricker, B. H., Hofman, A., Uitterlinden, A. G., Levy, D., Boerwinkle, E., Metspalu, A., Topol, E. J., Chakravarti, A., Gudnason, V., Psaty, B. M., Roden, D. M., Meitinger, T., Wichmann, H. E., Witteman, J. C. M., Barnard, J., Arking, D. E., Benjamin, E. J., Heckbert, S. R. & Kääb, S., Mar 2010, In: Nature genetics. 42, 3, p. 240-244 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

396 Scopus citations

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

Sotoodehnia, N., Isaacs, A., De Bakker, P. I. W., DÖrr, M., Newton-Cheh, C., Nolte, I. M., Van Der Harst, P., Müller, M., Eijgelsheim, M., Alonso, A., Hicks, A. A., Padmanabhan, S., Hayward, C., Smith, A. V., Polasek, O., Giovannone, S., Fu, J., Magnani, J. W., Marciante, K. D., Pfeufer, A., & 83 othersGharib, S. A., Teumer, A., Li, M., Bis, J. C., Rivadeneira, F., Aspelund, T., KÖttgen, A., Johnson, T., Rice, K., Sie, M. P. S., Wang, Y. A., Klopp, N., Fuchsberger, C., Wild, S. H., Leach, I. M., Estrada, K., VÖlker, U., Wright, A. F., Asselbergs, F. W., Qu, J., Chakravarti, A., Sinner, M. F., Kors, J. A., Petersmann, A., Harris, T. B., Soliman, E. Z., Munroe, P. B., Psaty, B. M., Oostra, B. A., Cupples, L. A., Perz, S., De Boer, R. A., Uitterlinden, A. G., VÖlzke, H., Spector, T. D., Liu, F. Y., Boerwinkle, E., Dominiczak, A. F., Rotter, J. I., Van Herpen, G., Levy, D., Wichmann, H. E., Van Gilst, W. H., Witteman, J. C. M., Kroemer, H. K., Kao, W. H. L., Heckbert, S. R., Meitinger, T., Hofman, A., Campbell, H., Folsom, A. R., Van Veldhuisen, D. J., Schwienbacher, C., O'Donnell, C. J., Volpato, C. B., Caulfield, M. J., Connell, J. M., Launer, L., Lu, X., Franke, L., Fehrmann, R. S. N., Te Meerman, G., Groen, H. J. M., Weersma, R. K., Van Den Berg, L. H., Wijmenga, C., Ophoff, R. A., Navis, G., Rudan, I., Snieder, H., Wilson, J. F., Pramstaller, P. P., Siscovick, D. S., Wang, T. J., Gudnason, V., Van Duijn, C. M., Felix, S. B., Fishman, G. I., Jamshidi, Y., Ch Stricker, B. H., Samani, N. J., Kääb, S. & Arking, D. E., Dec 1 2010, In: Nature genetics. 42, 12, p. 1068-1076 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

274 Scopus citations

Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling

Ho, J. E., Chen, W. Y., Chen, M. H., Larson, M. G., McCabe, E. L., Cheng, S., Ghorbani, A., Coglianese, E., Emilsson, V., Johnson, A. D., Walter, S., Franceschini, N., O'Donnell, C. J., Dehghan, A., Lu, C., Levy, D., Newton-Cheh, C., Lin, H., Felix, J. F., Schreiter, E. R., & 4 othersVasan, R. S., Januzzi, J. L., Lee, R. T. & Wang, T. J., Oct 1 2013, In: Journal of Clinical Investigation. 123, 10, p. 4208-4218 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

94 Scopus citations

Common genetic determinants of vitamin D insufficiency: A genome-wide association study

Wang, T. J., Zhang, F., Richards, J. B., Kestenbaum, B., Van Meurs, J. B., Berry, D., Kiel, D. P., Streeten, E. A., Ohlsson, C., Koller, D. L., Peltonen, L., Cooper, J. D., O'Reilly, P. F., Houston, D. K., Glazer, N. L., Vandenput, L., Peacock, M., Shi, J., Rivadeneira, F., McCarthy, M. I., & 56 othersAnneli, P., De Boer, I. H., Mangino, M., Kato, B., Smyth, D. J., Booth, S. L., Jacques, P. F., Burke, G. L., Goodarzi, M., Cheung, C. L., Wolf, M., Rice, K., Goltzman, D., Hidiroglou, N., Ladouceur, M., Wareham, N. J., Hocking, L. J., Hart, D., Arden, N. K., Cooper, C., Malik, S., Fraser, W. D., Hartikainen, A. L., Zhai, G., Macdonald, H. M., Forouhi, N. G., Loos, R. J. F., Reid, D. M., Hakim, A., Dennison, E., Liu, Y., Power, C., Stevens, H. E., Jaana, L., Vasan, R. S., Soranzo, N., Bojunga, J., Psaty, B. M., Lorentzon, M., Foroud, T., Harris, T. B., Hofman, A., Jansson, J. O., Cauley, J. A., Uitterlinden, A. G., Gibson, Q., Järvelin, M. R., Karasik, D., Siscovick, D. S., Econs, M. J., Kritchevsky, S. B., Florez, J. C., Todd, J. A., Dupuis, J., Hyppönen, E. & Spector, T. D., 2010, In: The Lancet. 376, 9736, p. 180-188 9 p.

Research output: Contribution to journal › Article › peer-review

1348 Scopus citations

Combining biomarkers and imaging for short-term assessment of cardiovascular disease risk in apparently healthy adults

Gore, M. O., Ayers, C. R., Khera, A., Defilippi, C. R., Wang, T. J., Seliger, S. L., Nambi, V., Selvin, E., Berry, J. D., Hundley, W. G., Budoff, M., Greenland, P., Drazner, M. H., Ballantyne, C. M., Levine, B. D. & de Lemos, J. A., Aug 4 2020, In: Journal of the American Heart Association. 9, 15, e015410.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Coexposure to Borrelia burgdorferi and Babesia microti does not worsen the long-term outcome of Lyme disease

Wang, T. J., Liang, M. H., Sangha, O., Phillips, C. B., Lew, R. A., Wright, E. A., Berardi, V., Fossel, A. H. & Shadick, N. A., 2000, In: Clinical Infectious Diseases. 31, 5, p. 1149-1154 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

40 Scopus citations

Clinical correlates of circulating visfatin levels in a community-based sample

Ingelsson, E., Larson, M. G., Fox, C. S., Yin, X., Wang, T. J., Lipinska, I., Pou, K. M., Hoffmann, U., Benjamin, E. J., Keaney, J. F. & Vasan, R. S., May 2007, In: Diabetes care. 30, 5, p. 1278-1280 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

41 Scopus citations

Clinical and genetic correlates of growth differentiation factor 15 in the community

Ho, J. E., Mahajan, A., Chen, M. H., Larson, M. G., McCabe, E. L., Ghorbani, A., Cheng, S., Johnson, A. D., Lindgren, C. M., Kempf, T., Lind, L., Ingelsson, E., Vasan, R. S., Januzzi, J., Wollert, K. C., Morris, A. P. & Wang, T. J., Nov 2012, In: Clinical chemistry. 58, 11, p. 1582-1591 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

101 Scopus citations

Thomas J Wang

Research output

Search results