Search All UT System Experts

The Nancy B. and Jake L. Hamon Center for Therapeutic Oncology Research

Search results

  • 2011

    How do we safely get people to stop smoking?

    Lam, D. C. L. & Minna, J. D., Nov 2011, In: Cancer Prevention Research. 4, 11, p. 1724-1727 4 p.

    Research output: Contribution to journal › Review article › peer-review

    2 Scopus citations

  • Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy

    Yang, F., Tang, X., Riquelme, E., Behrens, C., Nilsson, M. B., Giri, U., Varella-Garcia, M., Byers, L. A., Lin, H. Y., Wang, J., Raso, M. G., Girard, L., Coombes, K., Lee, J. J., Herbst, R. S., Minna, J. D., Heymach, J. V. & Wistuba, I. I., Aug 15 2011, In: Cancer research. 71, 16, p. 5512-5521 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    53 Scopus citations

  • Irreparable complex DNA double-strand breaks induce chromosome breakage in organotypic three-dimensional human lung epithelial cell culture

    Asaithamby, A., Hu, B., Delgado, O., Ding, L. H., Story, M. D., Minna, J. D., Shay, J. W. & Chen, D. J., Jul 2011, In: Nucleic acids research. 39, 13, p. 5474-5488 15 p.

    Research output: Contribution to journal › Article › peer-review

    42 Scopus citations

  • Knockdown of oncogenic KRAS in non-small cell lung cancers suppresses tumor growth and sensitizes tumor cells to targeted therapy

    Sunaga, N., Shames, D. S., Girard, L., Peyton, M., Larsen, J. E., Imai, H., Soh, J., Sato, M., Yanagitani, N., Kaira, K., Xie, Y., Gazdar, A. F., Mori, M. & Minna, J. D., Feb 2011, In: Molecular Cancer Therapeutics. 10, 2, p. 336-346 11 p.

    Research output: Contribution to journal › Article › peer-review

    137 Scopus citations

  • Mechanistic contribution of ubiquitous 15-lipoxygenase-1 expression loss in cancer cells to terminal cell differentiation evasion

    Moussalli, M. J., Wu, Y., Zuo, X., Yang, X. L., Wistuba, I. I., Raso, M. G., Morris, J. S., Bowser, J. L., Minna, J. D., Lotan, R. & Shureiqi, I., Dec 2011, In: Cancer Prevention Research. 4, 12, p. 1961-1972 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    35 Scopus citations

  • Molecular Biology of Lung Cancer: Clinical Implications

    Larsen, J. E. & Minna, J. D., Dec 2011, In: Clinics in Chest Medicine. 32, 4, p. 703-740 38 p.

    Research output: Contribution to journal › Review article › peer-review

    182 Scopus citations

  • Multipotent capacity of immortalized human bronchial epithelial cells

    Delgado, O., Kaisani, A. A., Spinola, M., Xie, X. J., Batten, K. G., Minna, J. D., Wright, W. E. & Shay, J. W., 2011, In: PloS one. 6, 7, e22023.

    Research output: Contribution to journal › Article › peer-review

    58 Scopus citations

  • Oral iloprost improves endobronchial dysplasia in former smokers

    Keith, R. L., Blatchford, P. J., Kittelson, J., Minna, J. D., Kelly, K., Massion, P. P., Franklin, W. A., Mao, J., Wilson, D. O., Merrick, D. T., Hirsch, F. R., Kennedy, T. C., Bunn, P. A., Geraci, M. W. & Miller, Y. E., Jun 2011, In: Cancer Prevention Research. 4, 6, p. 793-802 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    90 Scopus citations

  • Pivotal role of epithelial cell adhesion molecule in the survival of lung cancer cells

    Hase, T., Sato, M., Yoshida, K., Girard, L., Takeyama, Y., Horio, M., Elshazley, M., Oguri, T., Sekido, Y., Shames, D. S., Gazdar, A. F., Minna, J. D., Kondo, M. & Hasegawa, Y., Aug 2011, In: Cancer Science. 102, 8, p. 1493-1500 8 p.

    Research output: Contribution to journal › Article › peer-review

    24 Scopus citations

  • Robust gene expression signature from formalin-fixed paraffin-embedded samples predicts prognosis of non-small-cell lung cancer patients

    Xie, Y., Xiao, G., Coombes, K. R., Behrens, C., Solis, L. M., Raso, G., Girard, L., Erickson, H. S., Roth, J., Heymach, J. V., Moran, C., Danenberg, K., Minna, J. D. & Wistuba, I. I., Sep 1 2011, In: Clinical Cancer Research. 17, 17, p. 5705-5714 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    128 Scopus citations

  • SMAC mimetic (JP1201) sensitizes non-small cell lung cancers to multiple chemotherapy agents in an IAP-dependent but TNF-α-independent manner

    Greer, R. M., Peyton, M., Larsen, J. E., Girard, L., Xie, Y., Gazdar, A. F., Harran, P., Wang, L., Brekken, R. A., Wang, X. & Minna, J. D., Dec 15 2011, In: Cancer research. 71, 24, p. 7640-7648 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    47 Scopus citations

  • Sporadic breast cancer patients' germline DNA exhibit an AT-rich microsatellite signature

    Galindo, C. L., McIver, L. J., Tae, H., McCormick, J. F., Skinner, M. A., Hoeschele, I., Lewis, C. M., Minna, J. D., Boothman, D. A. & Garner, H. R., Apr 2011, In: Genes Chromosomes and Cancer. 50, 4, p. 275-283 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • STAT3 mediates resistance to MEK inhibitor through microRNA miR-17

    Dai, B., Meng, J., Peyton, M., Girard, L., Bornmann, W. G., Ji, L., Minna, J. D., Fang, B. & Roth, J. A., May 15 2011, In: Cancer research. 71, 10, p. 3658-3668 11 p.

    Research output: Contribution to journal › Article › peer-review

    78 Scopus citations

  • Targeted therapies for lung cancer: Clinical experience and novel agents

    Larsen, J. E., Cascone, T., Gerber, D. E., Heymach, J. V. & Minna, J. D., Nov 2011, In: Cancer Journal. 17, 6, p. 512-527 16 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    93 Scopus citations

  • The national lung screening trial: Overview and study design

    Gatsonis, C. A., Aberle, D. R., Berg, C. D., Black, W. C., Church, T. R., Fagerstrom, R. M., Galen, B., Gareen, I. F., Goldin, J., Gohagan, J. K., Hillman, B., Jaffe, C., Kramer, B. S., Lynch, D., Marcus, P. M., Schnall, M., Sullivan, D. C., Sullivan, D., Zylak, C. J., Cagnon, C., & 1,319 othersCody, D., Fletcher, G., Flynn, M. J., Judy, P. F., Kruger, R., Larke, F. J., McNitt-Gray, M., Payne, T., Anthony Seibert, J., Wu, X., Abbott, G., Amorosa, J. K., Barr, R. G., Boiselle, P. M., Chiles, C., Clark, R., Coppage, L., Falk, R., Fishman, E. K., Gemmel, D., Goldin, J. G., Goodman, E., Hart, E. M., Hazelton, T., Johnson, E., Kazerooni, E., McComb, B., McLennan, G., Munden, R. F., Ravenel, J., Sullivan, M., Swensen, S. J., Torigian, D. A., Vydareny, K. H., Worrell, J. A., Balkin, P., Fouad, M., Freedman, M. T., Garg, K., Gelmann, E. P., Gierada, D. S., Hocking, W., Inampudi, S., Isaacs, C., Kvale, P., Mann, H., Manor, W., Nath, H., Reding, D., Spizarny, D. L., Strollo, D. C., Waltz, J., Chen, M. H., Duan, F., Izmirilian, G., Pinsky, P., Prorok, P. C., Miller, A. B., Edelman, M. J., Evans, W. K., Fontana, R. S., Machtay, M., Clark, K. W., Clingan, K. L., Ford, M. B., Márquez, G., Moore, S. M., Ohan, P., Payne, T. J., Peace, S., Rosenbaum, J. L., Barr, R., Black, W., Torigian, D., Vydareny, K., Worrell, J., Young, R. C., Alberts, D., DeMets, D., Greenwald, P., Jacobs, P., McLoud, T. C., Naidich, D. P., Tatum, J., Sausville, E. A., Burke, W., Colice, G., Edwards, B., Emerson, S., Fletcher, J., Green, S., Harris, R., Klein, J. S., Korn, E. L., Mayer, R., Selby, J. V., Sturges, D. W., Turnbull, B. W., Watson, T. J., Baylin, S., Caporaso, N., Dennis, P., Dubinett, S., Franklin, W., Grizzle, W., Hirsch, F., Massion, P., McKeeta-Frobeck, K., Minna, J., Patz, E., Spitz, M., Berg, C. B., Corle, D., Hu, P., Izmirlian, G., Gaegler, J., Hoffman, S., Jackson, C., Lange, E., Papadopoulos, E., Gatsonis, C., Gareen, I., Apgar, C., Boyle, A., Caldwell, T., Fredericks, N., Harbison, D., Hartfeil, D., Jones, S., King, S., Mahon, I., Medina, R., Masiejczyk, C., Zamora, P., Brastater, H., Iyer, V., George, J., Gopalakrishnan, D., Blair, P., Bradley, M., Crozier, C., Oh, M., Spiese, N., Steward, C., Kelly-Truran, M., Thompson, T., Cunningham, E., Levering, A., McMurtrie, K., Nahill, M., Snowden, S., Smith, K., Wilton, F., Welsh, T., Welsh, R., Christie, W., Clabo, S., Clune, R., Cunningham, N., Downs, J., Dymond, L., Falcone, J., Harris, S., Harvey, P., Hill, J., Hill, L., Letizia, D., Looney, K., McGinley, H., Mean, A., Moore, M., Norton, R., Ortico, V., Sabina, S., Sole, R., Stetz, J., Ssali, A., Stubblefield, J., Taylor, T., White, S., Lu, B., Adams, A., Baum, S., Blevins, M., Fox, P., Girardi, V., Gorelick, J., Hunt, E., McMullen, Q., Meganathan, K., Rendas-Baum, R., Sicks, J. D., Snyder, B., Yeh, M., Duggan, M., Souza, C., Cahill, J., Brewer, B. K., O'Brien, B., Devereux, G., Fritz, M. S., Galbraith, M., Harkins, J., Keating, K. J., Midkiff, K., Singh, U., Zimmerman, T., Payte, N., Price, H., Caughman, C., Chanapatna, R., Florzyk, M., Lee, A., Morgan, A., Yang, J., Ellen Martinusen, L., McSwain, J., Rosario, R., Singh, J., DeBaugh, R. A., Campleman, S., Mesnard, M., Ragard, L., Lewis, T., Roberts, L. M., Narayanaswami, V., Ralda, V., Lake, W., Riley, T., Clapp, J. B., Austin, J., Irons, B., Xu, F. F., Jones, G. C., Young, M., Goodman, A., Kibic, C., Sheridan, P., Kadish, N., Moline, D., Phillips, R., Adkinson, M., Creed, D., DeCoste, T., Gembala, D., Hurst, S., King, E., Knowles, J., McBride, P., Pangburn, P., Preston, J., Stokes, K., Tesch, P., Wenmoth, S., Galocy, L., Mandley, D., Orvis, G., Dial, A., Clark, L., Cohen, L., Gerber, J., Jamis-Dow, C., Makariou, E., Smith, E., Garrett, A., McGuire, C., Neff, S., Riley, T., Cantrell, S., Marsh, G., Wray, C., Yondonsambuu, B., Giles, U., Ford, M., Brown, V., Evangelista, A. L., Hammond, T., Nickel, J., Brangan, M., Lee, M., Lin, C., Adkins, E., Armah, G., Blue, C., Cooke, V., Gray, N., Gustitis, M., Hawkins, L., Isaacs, G., Kim, M., King, M., Kumbalasiri, K., Laura, R., McDaniel, K., Mulugeta, A., Riley, L., Sorrell, S., Thomas, W., Woodard, L., Johnson, C. C., Tammemagi, M., Spizarny, D., Zylak, C., Flynn, M., Sen, G. J., Sankey, S., Schultz, L., Albertsen, K., Broski, K., Kucera, G., Poler, K., Spoutz-Ryan, C., Thomas, D., Griesemer, E., Kwit, B., Fantuz, P., McLellan, B., Simmons, D., Hafeez, Y., Maddy, N., Davis, L., Estell, R., Kozakowski, S., Rowe, J., Stanley, M., Zhang, X., Frebes, M. E., Paquette, M., Tecmire, M., Young, L., Greene, D., Hill, C., Young, K., Bellware, K., Bohn, K., Caird, N., Fink, H., Fiarman, S., Houston, M., Jolly, A., Krzeczkowski, C., Mack, C., Murray, L., Nanovski, A., Rempinski, D., Tumberlinson, H., William, D., Eldridge-Smith, E., Graves, V., Szabo, N., Crump, J., Kruger, R., Greenlee, R., Lappe, K., Multerer, D., Kriescher, D., Vieth, A., Wein, S., Fuehrer, D., Gjertson, C., Krebsbach, J., Kuhlka, C., Luttrop, K., Netzer, J., Wegner, J., Fischer, V., Mathiesen-Viergutz, K., Kofka, K., Jablonsky, N., Johnson, B., Kitchner, T., Mueller, L., Rueth, A., Wachholz, S., Bohman, K., Bruger, M., Kramer, K. R., Kuenhold, K., Mueller, C., Mueller, C., Multerer, L., Zahradka, S., Alkilidar, J., Bhattacharjee, N., Cangelosi, C., Carlson, R., Coppens, A., Cousins, M., Edelstein, B., Gerndt, K., Heffernon, J., Hinke, T., Hinson, M., Hutchins, L., Lieberman, K., Mulligan, G., Omoba, E., Risa, T., Sheflin, J., Swan, T., Warner, J., Williams, A., Yokochi, L., Adaniya, R., Glanz, K., Navin, J., Shambaugh, V., Tabrah, F., Willcox, B., Williams, P., He, Q., Jenkins, V., Bow, K., Tsukamoto, J., Hyun, S., Brown, E., Morrow, H., Stryker, K., Shiratori, H., Lau, P., Au, B., Francis, W., Bolan, L., Brooke, J., Calulot, M., Chun, V., Rabanal, K., Tani, J., Lewis, C., Morfit, J., Brunst, A., Turner, L., Hino, G., Chung, A., Elbon-Copp, C., Huynh, W., Johnson, M., Nakano, E., Villaruz, L., Fouad, M. N., Bailey, W. C., Garver, R., Brawner, D., Malcomb, I., Morgan, D., Sanders, P. C., Sandy, A., Schwartz, M., Singh, S., Dransfield, M., Higgins, D., Moore, A., Acemgil, A., Blake, T., Lee, J., Quattlebaum, S., Schach, J., Martin, T., Khatri, R., Gendi, W., Powell, B., Johnson, C., Sears, J., Jordan, S., Prayer, V., Walker, C., Johnson, M., Thompson, J., David Crawford, E., Bunn, P., Gamito, E., Ogden, S., Pretzel, S., Ramsay, L., Vaughn, C., Whiton, C., Sammons, D., Springhetti, L., Tenorio, S., Cadez, N., Laster, S., O'Donnell, C., Hughes, J., Livingston, J. G., Morrison, G., Moss, W., Mullennix, M., Peters, M., Sahin, H., Slear, M., Burek, M., Hill, C., Jewitt, E., Pena, R., Ordonez, E., Sammons, G., Hernandez, J., Reyes, A., Somoza, A., Oken, M., Bay, B., Edelman, K., Fox, T., Gaerte, S., Myra-Bloom, K., Plunkett, M., Olson, F., Rust, P., Schneider, L., Trombley, B., Vahey, T., Bangerter, A., David-Schlegel, T., DesMarais, D., Frederickson, S., Geisser, M., Portnov, N., Silverman, G., Stahan, F., Vuong, S., Watt, G., Woodside, J., Zirbes, A., Breer, S., Haselhuhn, C., Longden, C., Mueller, C., Rice, M., Warren, D., Collins, S., Levi, S., Manual, J., Matous, L., Olsson, P., Peterson, S., Rogers, C., Steele, M. L., Beckmann, P., Jurjans, L., Terrian, S., Fraki, S., Fronheiser, M., Heinrichs, L., Kirby, D., Seivert, J., Steinberg, C., Watry, M., Boyle, K., Burnside, A., Kiffmeyer, R., Mosiman, W., Bailey, A., Byrnes, P., Stark, L., Weston, M., Whistler, D., Cordes, J., Engelhard, D., Becker, J., Bradley, P., Fisher, J., McLaughlin, H., Mendez, A. M., Miller, D., Ronan, R., Siga, B., Weissfeld, J. L., Salerno, M. B., Schragin, J., Strollo, D., Warfel, T. E., Wolfe, P. W., Antico, D. A., Bee, M. T., Bittner, D. F., Corey, W. T., Hawkins, R. A., Herbick, W. T., Karwat, M. F., Leonard, K. J., Petrochko, C. N., Pickering, S. F., Smart, P. E., Walters, P. J., Zehner, J. A., Augustine, K., Misko, S., Richel, M., Riley, M. A., Warren, L., McDonough, K., Rozanok, B., Helms, J., Olson, P., Uttecht, S., Wirth, M., Atkins, R., Clement, L., Gurtner, D., Jones, L., Buys, S. S., Drosten, R., Murray, K., Nowers, K., Jenkins, P., Tripp, D., Herron, G., Van Stam, E., Varner, J., O'Toole, K., Olson, C., Omori, D., Andersen, A., Argyle, N., Avrin, J., Bacon, J., Broschinsky, M., Montalbo, C., Nolan, K., Randall, A., Schleip, K., Sheltra, S. J., Tischner, R., Toyn, C., Turner, K., Whittaker, B., Wicklander, E., Wolf, J., Baiton, C., Doi, B., Childs, J., Gren, L., Watson, D., Jones, T., Neilson, B., Ahumada, H., Bourija, H., Brown, C., Ferris, B., Hadfield, L., Hansen, K., Koford, J., Kopesec, S., Lloyd, A., Lofthouse, M., Matinkhah, S., May, V., Nichols, S., Nieves, A., Oviatt, M., Richardson, N., Rowley, A. L., Sandberg, E., Dave Scholl, S., Seguin, L., Shea, D., Smith, S., Street, P. A., Walters, M., Weiben, R., Wilcox, L., Zisumbo, R., Beck, T. M., Waltz, J. S., Ball, S., Burt, T. B., Daniel, E. N., DeMordaunt, Q. A., Fisher, M. T., Fuchs, M. A., Hubler, B. E., Jennings, C. J., Lane, R. H., Leymaster, C. E., Macey, L. C., Marx, S. V., Maxwell, J. R., Nelson, B. B., Fairbanks, J., Wohlers, B., Heinz, J., Berreth, K., Marshall, R., Brekke, J., Jones, K., Barrow, A., Bashford, D., Clot, B., Cook, T., Dobson, L., Hamilton-Foss, A., Hanson, W., Hyder, J. E., Lewis-Burke, C., Mitchell, S., Osterhout, M., Patella, K., Peterson, P., Schornak-Curtis, S., Sirianni, L., Stoller, L., Vigeant, K., Whistle, C., Yates, J., Andriole, G., Claire Anderson, D., Bhalla, S., Bierhals, A. J., Bronfman, J., Glazer, H. S., Gutierrez, F. R., Geisse, G., Kotner, L. M., Javidan-Nejad, C., Rezai, K., Sagel, S. S., Semenkovich, J. W., Siegel, M. J., Sorrel, D., Woodard, P. K., Engelhart, D., Haverman, R., Campbell, A., Gardner, V., Gherardini, D., Hoese, L., Holdener, R., Ledbetter, L., Nieters, P., Reiners, C., Wade, J., Wiseman, M., Rueweler, P., Williams, R., Chi, D., Budd, T., Webb, J., Stolin, C., Garrett, K., Fleming, E., Freesmeier, E., Frye, J., Graham, D., Kaemmerer, H., Nevilles, J., Taylor, K., Blaine, J., Clark, K., Gierada, D., Koppel, P., Maffitt, D., Moore, S., Molton, J., Phillips, S., Prior, F., Wolfsberger, M., Cosas, A., Kim, S., Kim, M., Liang, Y., Pilgram, T., Haas, A., Hartwell, D., Roeshe, D., Lowery, A., Meese, S., Naughton, K., Yoffie, R., Smith, K., Schwartzstein, R., Lin, P. J. P., Parritt, T. A., Grady, E. A., Damon, L., Gard, S., Griggs, R., Potemkin, A., Pollock, M. M., Clellan, S. M., Laron, M., Owens, T., Costello, P., Jacobson, F. L., Hunsaker, A. R., Spirn, P. W., Trotman-Bickenson, B., Christopoulos, V. E., Kazda, I. K., MacDougall, R. C., Walsh, A., Nawfel, R. D., Berger, R., Chan, P., Delano, M., Geiger, J., Krinopol, C., McGinnis, A. D., McLaughlin, A. M., Weatherby, R., Tung, G., Maineiro, M., Camara, L., Cobb, C., Foley, S., Morrell, E., Romano, D., Guillette, D., Smith, W., Aisner, J., Backer, M., Bramwitt, M., De Caravalho, V., Epstein, R., Joyce, P., Langenfeld, J. E., Reinert, A., Team, R., DeMarco, K., Lutzker, S., Musanti, R., Shiff, S., Wolfsohn, T., Hudak, C., Hugill, A., Furlong, M., Weslowsky, E., Carmen, S., Foster, D. L., Hansen, K., Pennetta, B., White, L. V., Tokarz, R., Trotta, M., Birofka, A., Kasales, C. J., Lewis, P. J., Weaver, J. B., Lenz, S. B., Barrett, A. C., Dauphinais, R., Heinz, J. R., Siemionko, M. K., Taplin, A., Wasson, L. S., DeAlmeida, L., Longacre, S., Meagher, K., Moser, C. M., Lawlor, J. K., O'Quinn, C., Krieger Black, N. E., Bradley, H. L., Bronson, J. K., Cosgrove, T., Haron, M. K., King, D., Mazuerk, P. M., O'Donnell, N. F., Pluta, D. J., Sackett, T. J., Turgeon, G. D., Albano, H., Bell, C., Bergen, J., Bizer, G., Carmichael, N. M., Cimis, C., Davis, S., DeAngelis, T., Fellows, G., Fenton, C., Ferola, J., Gankiewicz, N., Hastings, D., Howell, C., Johnson, M. E., Krisk, M., Lancor, H., Leary, C., LeBlanc, M., Leming, A., Leming, M., Mead, D., Milacek, M., Mood, J., Nordstrom, H., Palazzolo, C., Pierce, J., Remitz, R. P., Rider, J., Robbins, K. A., Sleasman, B., Spaulding, J., Vashel, C., Welch, A., White, L., Whitty, M., Williams, A. M., Karellas, A., Grayson, L., McCalister-Cross, C., Mesquita, S., Nguyen, A., Myers, L. N., Deaton, E., Maxfield, S., Thomas, K., Allen, P., Brooks, D., Chadwell, C., Couch, E., Devore, A., Flores, R., Francis, M., Landes, S., Mattingly, J., Oechsli, M., Pitino, B., Sams, S., Soukhanova, O., Bland, P., Bube, S., Hoffa, T., McElsain, B., Johnson, D., Francow, C., Johnson, S., Senn, P., Horton, K. M., Lawler, L. P., Bradford, L., Christensen, G., Bishop, J., Motley, L., Robertson, B., Stewart, R., Guzman, C., Blake, H. B., Bradford, H., Bradford, J., Burner, J., Kasecamp, J., Kaufmann, J. B., Kimball, D., Lewis, Z., Moesinger, S., Walsh, S., Taylor, K., Yung, R., Zeng, M., Gambill, G., Merrill, S., Mahesh, M., Johnson, E. A., Jolies, H. I., Kuzo, R. S., Morin, R. L., Abaya, R., Chewar, D., Shwarts, P., Allen, S., Manning, S., Awan, M. A. Z., Clinic, M., Jacksonville, Beagle, F. L., Cape, D., Zeiger, T., Amendolare, L., Bahr, N., Belyea, M., Berg, T., Burkhard, M., Cottrell, L., BeAngelis, K., Bvorak, M., Heather, L., Gay, B., Hatton, K., Jacoby, S., Kennedy, V., Krach, K., Laughren, M., Lavergne, C., Lawrence, M., Lynch, J., McDonald, A., Mestas, F., Moody, J., O'Brien, C., Pitts, J., Polding, B., Richardson, L., Robinson, K., Warren, A., Washburn, H., Wilson, E., Zagarra, L., Batton, K. M., Chellini, D., DeWitt, K., Fleming, D. R., Newton-Foster, C., MacDonald, R., Ott, J., Peterson, J., Sallas, M., Teepe, M., Thomas, R., Torrence, K., Hildestad, J., Hartman, T. E., Jett, J. R., McCollough, C. H., Midthun, B. E., Andrist, B. R., Hanson, N. E., Sathre, C. L., Schroeder, L. B., Sheeran, J. R., Walters, L. C., Andrist, C. L., Bungum, A. O., Bornhorst, C. L., Beno, B. M., Krpata, T. S., Lambrecht, A. M., McKey, C. M., Prudoehl, B. K., Richter, H. R., Brisendine, A., Adrales-Bentz, T., Arnold, K., Benjamin, B., Bodd, A., Keller, J., Saunders, T., Spicker, P., Shannon, S., Bailey, L., Comer, H., Espiritu, J., Helwi, S., Mack-Pipkin, B., Tockman, M., Evans, B., Wadhwa, N., Baptiste, N., Eysmans, C., Vera-Gonzalez, N., Hamm, L., Harjani, V., Sear, A., Blackwell, S., Fernandez, A., Williams, E., Coleman, K. A., Afiat, J., Kirchoff, L., Bowman, R., Brothers, C., Cohen, B., Fields, N., Guzman, R., Monje, C., Sterling, W., Thorpe, L., White, K., Williams, B., Nekervis, E., Franco, A., Glick, L., Grigolo, M., Harts, Y., Migo, A., Rockwell, K. P., Stein, A., Weyls, R., Berns, E., Biringer, M. T., Pino, A. D., Dubbs, P., Fehrmann, G. M., Goodwin, A. L., Granger, L., Haglage, J., Hirschy, J., King, M., Kristopher, J. W., Mac, N. M., Mahoney, G., Markarian, A., Ramirez, M., Taylor, M., West, K. M., Sullivan, M. A., Matthews, C. C., Jones, J., Cole, A., Dow, P., Fearon, J., Fodera, B., Ginther, B., McCall, R. L., Williams, S., Young, S., Juul, C., LaFleur, A., Lohmann, K., Pineda, L., Schmidt, A., Wright, S., Greenup, S., McNulty, K., Pawlak, S., Porter, H., Lanning, T., Loria, D., Cook, A., Sky, J. A. H., Boulos, A., Dalal, P., Dickstein, B., DuChateau, A., Engartner, C., Evans, D. M., Evans, J., Evans, K., Gemmel, M., Hallsky, S., Hoffman, P., Hritz, C., Kerchum, L., Kolich, M., Kolich, M., Kolich, M., Kumar, N., Lobaugh, J., Love, C., Love, D., Love, M., Marchese, M., Nelson, D., Petkus, C., Petruzzi, M., Raver, C., Schuler, E., Schuler, P., Schultz, D., Kobistek, R., Jackson, J., Ziegler, J., Fleischer, J., Welch, L. L., Acerra, M., Brittain, B., Conklin, L., Cyphert, C., Delfosse, B., Franceshelli, L., Fuller, J., Garland, D., Gocala, P. J., Grunenwald, M., Kowalik, D., Kurjan, S. L., Lavernick, P., Maderitz, J., Metz, R., Quinn, R., Semansky, M., Smith, S., St.Claire, A., Taybus, P., Wisler, D., Zubena, K., Duda, C., Kay, P., Trapnell, P., Vlachou, M., Bigby, B. B., Gallego, A., Hamm, G., Spivak, J., Pollard, M., Brown, E., Campa, O., Carter, B., Clark, S., Flores, M., Ho, J., Lee, T., Lewis, B., McMahon, J., Momongan, L., Ngo, J., Perryman, A., Rivas, N., Romo, C., Sookpisal, K., Stone, L., Voight, B., Williams, C., Adams, K., Do, P., Engber, K., Henry, L., Khalili, M., Morales, S., O'Carroll, C., Quijano, J., Borgheian, S., Inatomi, R., Lorenzo, A., Lorenzo, D., Nyborg, G., Salazar, V., Woo, M., Beck, P., Beerman, P., Jacobsen, J., Voight, K., Allman, E., Chen, S., Farkas, C., Forter, I., Marcus, P., Matthews, L., Phillips, R., Silva-Gietzen, J., Sturgeon, E., Varner, G., Mullen, B., Stanford, W., Hoffman, E., Sprenger, K., Chapman, A., Crawford, K., Marietta, J., Kmetty, L., Meier, J., Pirotte, P., Rathmell, L., Hudson, M., Sieren, J., Cronin, P., Gross, B., Kelly, A., Patel, S., Pernicano, P., Holloway, L., Chalom, G., Henricks, E., Pool, J., Shepherd, D., Zapolski, D., Goodsitt, M., Hooks, H., Gefter, W., Lynn Werner, D., Smith, C. E., Choi, B. K., Lee, J. K., Holland, C., Matuza, J., Nosker, H. C., Russell, W., Cupp, S., O'Shea, M., Munden, R., Cates, M., Sanchez, E., Aganon-Acheta, M., Black, M., Blalock, D., Brown, C., Cromwell, H., Dunnington, J., Erasmus, J., Gladish, G., Gupta, S., Haynes, M. W., Hensley, T., Iyer, R. B., Madewell, J., Malbari, T., Marom, E. M., Morice, R., Rao, S., Sabloff, B., Scully, N. F., Tekchandani, S., Truong, M., Wicks, D., Geiser, W. R., Montague, J. L., Patel, M., Robinson, T., Donnelly, E. F., Thielke, E., Bell, A. M., Pickens, D. R., Bowman, W. A., Herron, T., Shone, D., Chin, B., Chen, M., Harmon, L., Hinshaw, L., Nelson, C., Biracree, D., Boyles, D., Burrough, A., Davis, A., Drake, E., Frost, E., Long, A., Bowman, E. & Dyer, S., Jan 1 2011, In: RADIOLOGY. 258, 1, p. 243-253 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    931 Scopus citations
  • 2010

    A catalog of genes homozygously deleted in human lung cancer and the candidacy of PTPRD as a tumor suppressor gene

    Kohno, T., Otsuka, A., Girard, L., Sato, M., Iwakawa, R., Ogiwara, H., Sanchez-Cespedes, M., Minna, J. D. & Yokota, J., Apr 2010, In: Genes Chromosomes and Cancer. 49, 4, p. 342-352 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    70 Scopus citations

  • Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling

    Sullivan, J. P., Spinola, M., Dodge, M., Raso, M. G., Behrens, C., Gao, B., Schuster, K., Shao, C., Larsen, J. E., Sullivan, L. A., Honorio, S., Xie, Y., Scaglioni, P. P., DiMaio, J. M., Gazdar, A. F., Shay, J. W., Wistuba, I. I. & Minna, J. D., Dec 1 2010, In: Cancer research. 70, 23, p. 9937-9948 12 p.

    Research output: Contribution to journal › Article › peer-review

    343 Scopus citations

  • ALK Inhibition for Non-Small Cell Lung Cancer: From Discovery to Therapy in Record Time

    Gerber, D. E. & Minna, J. D., Dec 14 2010, In: Cancer Cell. 18, 6, p. 548-551 4 p.

    Research output: Contribution to journal › Review article › peer-review

    195 Scopus citations

  • Alternative splicing of caspase 9 is modulated by the phosphoinositide 3-kinase/Akt pathway via phosphorylation of SRp30a

    Shultz, J. C., Goehe, R. W., Wijesinghe, D. S., Murudkar, C., Hawkins, A. J., Shay, J. W., Minna, J. D. & Chalfant, C. E., Nov 15 2010, In: Cancer research. 70, 22, p. 9185-9196 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    112 Scopus citations

  • An orthotopic lung tumor model for image-guided microirradiation in rats

    Saha, D., Watkins, L., Yin, Y., Thorpe, P., Story, M. D., Song, K., Raghavan, P., Timmerman, R., Chen, B., Minna, J. D. & Solberg, T. D., Jul 2010, In: Radiation research. 174, 1, p. 62-71 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations

  • A second genetic variant on chromosome 15q24-25.1 associates with lung cancer

    Liu, P., Yang, P., Wu, X., Vikis, H. G., Lu, Y., Wang, Y., Schwartz, A. G., Pinney, S. M., De Andrade, M., Gazdar, A., Gaba, C., Mandal, D., Lee, J., Kupert, E., Seminara, D., Minna, J., Bailey-Wilson, J. E., Spitz, M., Amos, C. I., Anderson, M. W., & 1 othersYou, M., Apr 15 2010, In: Cancer research. 70, 8, p. 3128-3135 8 p.

    Research output: Contribution to journal › Article › peer-review

    4 Scopus citations

  • A small-cell lung cancer genome with complex signatures of tobacco exposure

    Pleasance, E. D., Stephens, P. J., O'Meara, S., McBride, D. J., Meynert, A., Jones, D., Lin, M. L., Beare, D., Lau, K. W., Greenman, C., Varela, I., Nik-Zainal, S., Davies, H. R., Ordõez, G. R., Mudie, L. J., Latimer, C., Edkins, S., Stebbings, L., Chen, L., Jia, M., & 20 othersLeroy, C., Marshall, J., Menzies, A., Butler, A., Teague, J. W., Mangion, J., Sun, Y. A., McLaughlin, S. F., Peckham, H. E., Tsung, E. F., Costa, G. L., Lee, C. C., Minna, J. D., Gazdar, A., Birney, E., Rhodes, M. D., McKernan, K. J., Stratton, M. R., Futreal, P. A. & Campbell, P. J., Jan 14 2010, In: Nature. 463, 7278, p. 184-190 7 p.

    Research output: Contribution to journal › Article › peer-review

    911 Scopus citations

  • A susceptibility locus on chromosome 6q greatly increases lung cancer risk among light and never smokers

    Amos, C. I., Pinney, S. M., Li, Y., Kupert, E., Lee, J., De Andrade, M. A., Yang, P., Schwartz, A. G., Fain, P. R., Gazdar, A., Minna, J., Wiest, J. S., Zeng, D., Rothschild, H., Mandal, D., You, M., Coons, T., Gaba, C., Bailey-Wilson, J. E. & Anderson, M. W., Mar 15 2010, In: Cancer research. 70, 6, p. 2359-2367 9 p.

    Research output: Contribution to journal › Article › peer-review

    47 Scopus citations

  • Blasted cell line names

    Wang, J., Byers, L. A., Yordy, J. S., Liu, W., Shen, L., Baggerly, K. A., Giri, U., Myers, J. N., Ang, K. K., Story, M. D., Girard, L., Minna, J. D., Heymach, J. V. & Coombes, K. R., 2010, In: Cancer Informatics. 9, p. 251-255 5 p.

    Research output: Contribution to journal › Article › peer-review

  • Clinicopathological and therapeutic significance of CXCL12 expression in lung cancer

    Imai, H., Sunaga, N., Shimizu, Y., Kakegawa, S., Shimizu, K., Sano, T., Ishizuka, T., Oyama, T., Saito, R., Minna, J. D. & Mori, M., 2010, In: International Journal of Immunopathology and Pharmacology. 23, 1, p. 153-164 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    32 Scopus citations

  • Combination treatment with MEK and AKT inhibitors is more effective than each drug alone in human non- small cell lung cancer in vitro and in vivo

    Meng, J., Dai, B., Fang, B., Nebiyou Bekele, B., Bornmann, W. G., Sun, D., Peng, Z., Herbst, R. S., Papadimitrakopoulou, V., Minna, J. D., Peyton, M. & Roth, J. A., 2010, In: PloS one. 5, 11, e14124.

    Research output: Contribution to journal › Article › peer-review

    126 Scopus citations

  • Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer

    Liu, P., Vikis, H. G., Lu, Y., Wang, Y., Schwartz, A. G., Pinney, S. M., Yang, P., De Andrade, M., Gazdar, A., Gaba, C., Mandal, D., Lee, J., Kupert, E., Seminara, D., Minna, J., Bailey-Wilson, J. E., Amos, C. I., Anderson, M. W. & You, M., Feb 2010, In: Cancer Epidemiology Biomarkers and Prevention. 19, 2, p. 517-524 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    25 Scopus citations

  • DNA damage intensity in fibroblasts in a 3-dimensional collagen matrix correlates with the Bragg curve energy distribution of a high LET particle

    Roig, A. I., Hight, S. K., Minna, J. D., Shay, J. W., Rusek, A. & Story, M. D., Mar 2010, In: International Journal of Radiation Biology. 86, 3, p. 194-204 11 p.

    Research output: Contribution to journal › Article › peer-review

    10 Scopus citations

  • Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1α in non-small cell lung cancer cells

    Xu, L., Nilsson, M. B., Saintigny, P., Cascone, T., Herynk, M. H., Du, Z., Nikolinakos, P. G., Yang, Y., Prudkin, L., Liu, D., Lee, J. J., Johnson, F. M., Wong, K. K., Girard, L., Gazdar, A. F., Minna, J. D., Kurie, J. M., Wistuba, I. I. & Heymach, J. V., May 2010, In: Oncogene. 29, 18, p. 2616-2627 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    78 Scopus citations

  • Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy

    Sullivan, J. P., Minna, J. D. & Shay, J. W., Mar 2010, In: Cancer and Metastasis Reviews. 29, 1, p. 61-72 12 p.

    Research output: Contribution to journal › Review article › peer-review

    146 Scopus citations

  • Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer

    Hildebrandt, M. A. T., Komaki, R., Liao, Z., Gu, J., Chang, J. Y., Ye, Y., Lu, C., Stewart, D. J., Minna, J. D., Roth, J. A., Lippman, S. M., Cox, J. D., Hong, W. K., Spitz, M. R. & Wu, X., 2010, In: PloS one. 5, 8, e12402.

    Research output: Contribution to journal › Article › peer-review

    93 Scopus citations

  • Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer

    Kim, Y. H., Kwei, K. A., Girard, L., Salari, K., Kao, J., Pacyna-Gengelbach, M., Wang, P., Hernandez-Boussard, T., Gazdar, A. F., Petersen, I., Minna, J. D. & Pollack, J. R., Mar 2010, In: Oncogene. 29, 10, p. 1421-1430 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    68 Scopus citations

  • hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing

    Goehe, R. W., Shultz, J. C., Murudkar, C., Usanovic, S., Lamour, N. F., Massey, D. H., Zhang, L., Camidge, D. R., Shay, J. W., Minna, J. D. & Chalfant, C. E., Nov 1 2010, In: Journal of Clinical Investigation. 120, 11, p. 3923-3939 17 p.

    Research output: Contribution to journal › Article › peer-review

    95 Scopus citations

  • Identification of 5 novel genes methylated in breast and other epithelial cancers

    Hill, V. K., Hesson, L. B., Dansranjavin, T., Dallol, A., Bieche, I., Vacher, S., Tommasi, S., Dobbins, T., Gentle, D., Euhus, D., Lewis, C., Dammann, R., Ward, R. L., Minna, J., Maher, E. R., Pfeifer, G. P. & Latif, F., Mar 5 2010, In: Molecular Cancer. 9, 51.

    Research output: Contribution to journal › Article › peer-review

    69 Scopus citations

  • Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma

    Lockwood, W. W., Chari, R., Coe, B. P., Thu, K. L., Garnis, C., Malloff, C. A., Campbell, J., Williams, A. C., Hwang, D., Zhu, C. Q., Buys, T. P. H., Yee, J., English, J. C., MacAulay, C., Tsao, M. S., Gazdar, A. F., Minna, J. D., Lam, S. & Lam, W. L., Jul 2010, In: PLoS Medicine. 7, 7

    Research output: Contribution to journal › Article › peer-review

    83 Scopus citations

  • Knockdown of ZEB1, a master epithelial-to-mesenchymal transition (EMT) gene, suppresses anchorage-independent cell growth of lung cancer cells

    Takeyama, Y., Sato, M., Horio, M., Hase, T., Yoshida, K., Yokoyama, T., Nakashima, H., Hashimoto, N., Sekido, Y., Gazdar, A. F., Minna, J. D., Kondo, M. & Hasegawa, Y., Oct 2010, In: Cancer Letters. 296, 2, p. 216-224 9 p.

    Research output: Contribution to journal › Article › peer-review

    132 Scopus citations

  • Lung cancer cell lines: Useless artifacts or invaluable tools for medical science?

    Gazdar, A. F., Gao, B. & Minna, J. D., Jun 2010, In: Lung Cancer. 68, 3, p. 309-318 10 p.

    Research output: Contribution to journal › Review article › peer-review

    106 Scopus citations

  • Lung cancer cell lines as tools for biomedical discovery and research

    Gazdar, A. F., Girard, L., Lockwood, W. W., Lam, W. L. & Minna, J. D., Sep 8 2010, In: Journal of the National Cancer Institute. 102, 17, p. 1310-1321 12 p.

    Research output: Contribution to journal › Review article › peer-review

    162 Scopus citations

  • Met activation in non-small cell lung cancer is associated with de novo resistance to EGFR inhibitors and the development of brain metastasis

    Benedettini, E., Sholl, L. M., Peyton, M., Reilly, J., Ware, C., Davis, L., Vena, N., Bailey, D., Yeap, B. Y., Fiorentino, M., Ligon, A. H., Pan, B. S., Richon, V., Minna, J. D., Gazdar, A. F., Draetta, G., Bosari, S., Chirieac, L. R., Lutterbach, B. & Loda, M., Jul 2010, In: American Journal of Pathology. 177, 1, p. 415-423 9 p.

    Research output: Contribution to journal › Article › peer-review

    165 Scopus citations

  • MFSD2A is a novel lung tumor suppressor gene modulating cell cycle and matrix attachment

    Spinola, M., Falvella, F. S., Colombo, F., Sullivan, J. P., Shames, D. S., Girard, L., Spessotto, P., Minna, J. D. & Dragani, T. A., Mar 17 2010, In: Molecular Cancer. 9, 62.

    Research output: Contribution to journal › Article › peer-review

    31 Scopus citations

  • MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells and suggests a possible pathological relationship between SCLCs and NSCLCs

    Du, L., Schageman, J. J., Irnov, Girard, L., Hammond, S. M., Minna, J. D., Gazdar, A. F. & Pertsemlidis, A., 2010, In: Journal of Experimental and Clinical Cancer Research. 29, 1, 75.

    Research output: Contribution to journal › Article › peer-review

    65 Scopus citations

  • MRI-visible micellar nanomedicine for targeted drug delivery to lung cancer cells

    Guthi, J. S., Yang, S. G., Huang, G., Li, S., Khemtong, C., Kessinger, C. W., Peyton, M., Minna, J. D., Brown, K. C. & Gao, J., Feb 1 2010, In: Molecular Pharmaceutics. 7, 1, p. 32-40 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    179 Scopus citations

  • National lung cancer screening trial American college of radiology imaging network specimen biorepository originating from the contemporary screening for the detection of lung cancer trial (NLST, ACRIN 6654): Design, intent, and availability of specimens for validation of lung cancer biomarkers

    Patz, E. F., Caporaso, N. E., Dubinett, S. M., Massion, P. P., Hirsch, F. R., Minna, J. D., Gatsonis, C., Duan, F., Adams, A., Apgar, C., Medina, R. M. & Aberle, D. R., Oct 2010, In: Journal of Thoracic Oncology. 5, 10, p. 1502-1506 5 p.

    Research output: Contribution to journal › Editorial › peer-review

    23 Scopus citations

  • Non-small-cell lung cancer mrna expression signature predicting response to adjuvant chemotherapy

    Xie, Y. & Minna, J. D., Oct 10 2010, In: Journal of Clinical Oncology. 28, 29, p. 4404-4407 4 p.

    Research output: Contribution to journal › Editorial › peer-review

    16 Scopus citations

  • Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features

    Solis, L. M., Behrens, C., Dong, W., Suraokar, M., Ozburn, N. C., Moran, C. A., Corvalan, A. H., Biswal, S., Swisher, S. G., Bekele, B. N., Minna, J. D., Stewart, D. J. & Wistuba, I. I., Jul 15 2010, In: Clinical Cancer Research. 16, 14, p. 3743-3753 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    367 Scopus citations

  • Nuclear receptor expression defines a set of prognostic biomarkers for lung cancer

    Jeong, Y., Xie, Y., Xiao, G., Behrens, C., Girard, L., Wistuba, I. I., Minna, J. D. & Mangelsdorf, D. J., Dec 2010, In: PLoS Medicine. 7, 12, e1000378.

    Research output: Contribution to journal › Article › peer-review

    63 Scopus citations

  • Overcoming cancer cell resistance to Smac mimetic induced apoptosis by modulating cIAP-2 expression

    Petersen, S. L., Peyton, M., Minna, J. D. & Wang, X., Jun 29 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 26, p. 11936-11941 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    101 Scopus citations

  • Proteomic profiling identifies pathways dysregulated in non-small cell lung cancer and an inverse association of AMPK and adhesion pathways with recurrence

    Nanjundan, M., Byers, L. A., Carey, M. S., Siwak, D. R., Raso, M. G., Diao, L., Wang, J., Coombes, K. R., Roth, J. A., Mills, G. B., Wistuba, I. I., Minna, J. D. & Heymach, J. V., Dec 2010, In: Journal of Thoracic Oncology. 5, 12, p. 1894-1904 11 p.

    Research output: Contribution to journal › Article › peer-review

    55 Scopus citations

  • Radiogenomics predicting tumor responses to radiotherapy in lung cancer

    Das, A. K., Bell, M. H., Nirodi, C. S., Story, M. D. & Minna, J. D., Jul 2010, In: Seminars in Radiation Oncology. 20, 3, p. 149-155 7 p.

    Research output: Contribution to journal › Review article › peer-review

    36 Scopus citations

  • Sex determining region Y-box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung

    Yuan, P., Kadara, H., Behrens, C., Tang, X., Woods, D., Solis, L. M., Huang, J., Spinola, M., Dong, W., Yin, G., Fujimoto, J., Kim, E., Xie, Y., Girard, L., Moran, C., Hong, W. K., Minna, J. D. & Wistuba, I. I., Feb 9 2010, In: PloS one. 5, 2, e9112.

    Research output: Contribution to journal › Article › peer-review

    109 Scopus citations