Molecular Genetics

2008

Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons

Makita, T., Sucov, H. M., Gariepy, C. E., Yanagisawa, M. & Ginty, D. D., Apr 10 2008, In: Nature. 452, 7188, p. 759-763 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

158 Scopus citations

Entrainment of temperature and activity rhythms to restricted feeding in orexin knock out mice

Kaur, S., Thankachan, S., Begum, S., Blanco-Centurion, C., Sakurai, T., Yanagisawa, M. & Shiromani, P. J., Apr 18 2008, In: Brain Research. 1205, p. 47-54 8 p.

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Feedback regulation of cholesterol synthesis: Sterol-accelerated ubiquitination and degradation of HMG CoA reductase

DeBose-Boyd, R. A., Jun 2008, In: Cell Research. 18, 6, p. 609-621 13 p.

Research output: Contribution to journal › Article › peer-review

300 Scopus citations

Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone

Yang, J., Brown, M. S., Liang, G., Grishin, N. V. & Goldstein, J. L., Mar 2008, In: Chemtracts. 21, 3, p. 107-108 2 p.

Research output: Contribution to journal › Article › peer-review

Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone

Yang, J., Brown, M. S., Liang, G., Grishin, N. V. & Goldstein, J. L., Feb 8 2008, In: Cell. 132, 3, p. 387-396 10 p.

Research output: Contribution to journal › Article › peer-review

1006 Scopus citations

Inhibition of ghrelin O-acyltransferase (GOAT) by octanoylated pentapeptides

Yang, J., Zhao, T. J., Goldstein, J. L. & Brown, M. S., Aug 5 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 31, p. 10750-10755 6 p.

Research output: Contribution to journal › Article › peer-review

159 Scopus citations

Long chain Acyl-CoA synthetase 3-mediated phosphatidylcholine synthesis is required for assembly of very low density lipoproteins in human hepatoma Huh7 cells

Yao, H. & Ye, J., Jan 11 2008, In: Journal of Biological Chemistry. 283, 2, p. 849-854 6 p.

Research output: Contribution to journal › Article › peer-review

87 Scopus citations

Molecular motion at the critical point in lipid membranes

McConnell, H. & Radhakrishnan, A., Jul 15 2008, In: Biophysical journal. 95, 2, p. L22-L24

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

Infante, R. E., Wang, M. L., Radhakrishnan, A., Hyock, J. K., Brown, M. S. & Goldstein, J. L., Oct 7 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 40, p. 15287-15292 6 p.

Research output: Contribution to journal › Article › peer-review

368 Scopus citations

Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice

Liu, M., Thankachan, S., Kaur, S., Begum, S., Blanco-Centurion, C., Sakurai, T., Yanagisawa, M., Neve, R. & Shiromani, P. J., Oct 2008, In: European Journal of Neuroscience. 28, 7, p. 1382-1393 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

64 Scopus citations

PP2A-dependent disruption of centrosome replication and cytoskeleton organization in Drosophila by SV40 small tumor antigen

Kotadia, S., Kao, L. R., Comerford, S. A., Jones, R. T., Hammer, R. E. & Megraw, T. L., Oct 23 2008, In: Oncogene. 27, 49, p. 6334-6346 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Purified NPC1 protein: I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein

Infante, R. E., Abi-Mosleh, L., Radhakrishnan, A., Dale, J. D., Brown, M. S. & Goldstein, J. L., Jan 11 2008, In: Journal of Biological Chemistry. 283, 2, p. 1052-1063 12 p.

Research output: Contribution to journal › Article › peer-review

183 Scopus citations

Purified NPC1 protein II. Localization of sterol binding to a 240-amino acid soluble luminal loop

Infante, R. E., Radhakrishnan, A., Abi-Mosleh, L., Kinch, L. N., Wang, M. L., Grishin, N. V., Goldstein, J. L. & Brown, M. S., Jan 11 2008, In: Journal of Biological Chemistry. 283, 2, p. 1064-1075 12 p.

Research output: Contribution to journal › Article › peer-review

195 Scopus citations

Spontaneous atherosclerosis in aged lipoprotein lipase-deficient mice with severe hypertriglyceridemia on a normal chow diet

Zhang, X., Qi, R., Xian, X., Yang, F., Blackstein, M., Deng, X., Fan, J., Ross, C., Karasinska, J., Hayden, M. R. & Liu, G., Feb 2008, In: Circulation research. 102, 2, p. 250-256 7 p.

Research output: Contribution to journal › Article › peer-review

86 Scopus citations

Switch-like Control of SREBP-2 Transport Triggered by Small Changes in ER Cholesterol: A Delicate Balance

Radhakrishnan, A., Goldstein, J. L., McDonald, J. G. & Brown, M. S., Dec 6 2008, In: Cell Metabolism. 8, 6, p. 512-521 10 p.

Research output: Contribution to journal › Article › peer-review

436 Scopus citations

TGFβ mediates activation of transglutaminase 2 in response to oxidative stress that leads to protein aggregation

Shin, D. M., Jeon, J. H., Kim, C. W., Cho, S. Y., Lee, H. J., Jang, G. Y., Eui, M. J., Lee, D. S., Kang, J. H., Melino, G., Park, S. C. & Kim, I. G., Jul 2008, In: FASEB Journal. 22, 7, p. 2498-2507 10 p.

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress

Lutter, M., Sakata, I., Osborne-Lawrence, S., Rovinsky, S. A., Anderson, J. G., Jung, S., Birnbaum, S. G., Yanagisawa, M., Elmquist, J. K., Nestler, E. J. & Zigman, J. M., Jul 2008, In: Nature neuroscience. 11, 7, p. 752-753 2 p.

Research output: Contribution to journal › Article › peer-review

511 Scopus citations

Unsaturated fatty acids inhibit proteasomal degradation of insig-1 at a postubiquitination step

Joon, N. L., Zhang, X., Feramisco, J. D., Gong, Y. & Ye, J., Nov 28 2008, In: Journal of Biological Chemistry. 283, 48, p. 33772-33783 12 p.

Research output: Contribution to journal › Article › peer-review

80 Scopus citations

Urinary protein profiling with surface-enhanced laser desorption/ionization time-of-flight mass spectrometry in et_B receptor-deficient rats1

Raila, J., Kalk, P., Pfab, T., Thöne-Reineke, C., Godes, M., Yanagisawa, M., Schweigert, F. J. & Hocher, B., Aug 2008, In: Canadian Journal of Physiology and Pharmacology. 86, 8, p. 566-570 5 p.

Research output: Contribution to journal › Article › peer-review

Ventilatory long-term facilitation in mice can be observed during both sleep and wake periods and depends on orexin

Terada, J., Nakamura, A., Zhang, W., Yanagisawa, M., Kuriyama, T., Fukuda, Y. & Kuwaki, T., Feb 2008, In: Journal of applied physiology. 104, 2, p. 499-507 9 p.

Research output: Contribution to journal › Article › peer-review

78 Scopus citations

2007

[An improved method for isolation of single atrial myocyte from human heart].

Li, M. L., Zeng, X. R., Yang, Y., Liu, Z. F., Ding, Y. Y., Zhou, W. & Pei, J., Dec 25 2007, In: Sheng li xue bao : [Acta physiologica Sinica]. 59, 6, p. 858-864 7 p.

Research output: Contribution to journal › Article › peer-review

Amplification of the gene for SCAP, coupled with Insig-1 deficiency, confers sterol resistance in mutant Chinese hamster ovary cells

Lee, P. C. W., Liu, P., Li, W. P. & DeBose-Boyd, R. A., Sep 2007, In: Journal of lipid research. 48, 9, p. 1944-1954 11 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Composition fluctuations, chemical exchange, and nuclear relaxation in membranes containing cholesterol

Radhakrishnan, A. & McConnell, H., 2007, In: Journal of Chemical Physics. 126, 18, 185101.

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Contribution of orexin in hypercapnic chemoreflex: Evidence from genetic and pharmacological disruption and supplementation studies in mice

Deng, B. S., Nakamura, A., Zhang, W., Yanagisawa, M., Fukuda, Y. & Kuwaki, T., Nov 2007, In: Journal of applied physiology. 103, 5, p. 1772-1779 8 p.

Research output: Contribution to journal › Article › peer-review

111 Scopus citations

Elucidation of a Universal Size-Control Mechanism in Drosophila and Mammals

Dong, J., Feldmann, G., Huang, J., Wu, S., Zhang, N., Comerford, S. A., Gayyed, M., Anders, R. A., Maitra, A. & Pan Ph.D., D., Sep 21 2007, In: Cell. 130, 6, p. 1120-1133 14 p.

Research output: Contribution to journal › Article › peer-review

1936 Scopus citations

Expression of LPL in endothelial-intact artery results in lipid deposition and vascular cell adhesion molecule-1 upregulation in both LPL and ApoE-deficient mice

Wang, J., Xian, X., Huang, W., Chen, L., Wu, L., Zhu, Y., Fan, J., Ross, C., Hayden, M. R. & Liu, G., Jan 2007, In: Arteriosclerosis, thrombosis, and vascular biology. 27, 1, p. 197-203 7 p.

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins

Huang, H., Sun, F., Owen, D. M., Li, W., Chen, Y., Gale, M. & Ye, J., Apr 3 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 14, p. 5848-5853 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

455 Scopus citations

Hypoxia stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase through accumulation of lanosterol and hypoxia-inducible factor-mediated induction of insigs

Nguyen, A. D., McDonald, J. G., Bruick, R. K. & DeBose-Boyd, R. A., Sep 14 2007, In: Journal of Biological Chemistry. 282, 37, p. 27436-27446 11 p.

Research output: Contribution to journal › Article › peer-review

102 Scopus citations

Inhibition of hepatitis C virus replication by peroxidation of arachidonate and restoration by vitamin E

Huang, H., Chen, Y. & Ye, J., Nov 20 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 47, p. 18666-18670 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

70 Scopus citations

Mutations within the membrane domain of HMG-CoA reductase confer resistance to sterol-accelerated degradation

Lee, P. C. W., Nguyen, A. D. & DeBose-Boyd, R. A., Feb 2007, In: Journal of lipid research. 48, 2, p. 318-327 10 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Progress report on the Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure (HOMED-BP) study: Status at February 2004

Hosohata, K., Saito, S., Asayama, K., Ohkubo, T., Kikuya, M., Metoki, H., Obara, T., Kato, T., Hashimoto, J., Totsune, K., Miura, Y., Imai, Y., Arakawa, K., Fujishima, M., Fujii, J., Fukiyama, K., Hisamichi, S., Iimura, O., Ishii, M. & Omae, T. & 526 others, Saruta, T., Yoshinaga, K., Abe, I., Abe, K., Abukawa, T., Ashida, T., Dohba, N., Etoh, T., Fujimura, A., Fujita, T., Fukui, A., Gotoh, T., Hama, H., Hano, T., Hayashi, H., Hayashida, N., Hayashi, M., Hiramori, K., Hirai, Y., Hirata, Y., Hiwada, K., Hora, K., Ichikawa, S., Iida, T., Ikeda, T., Imaizumi, T., Ishikawa, K., Ito, I., Ito, M., Ito, S., Iwaoka, D., Kanamasa, K., Katagiri, T., Katayama, S., Kawamura, H., Kawano, Y., Kida, H., Kikuchi, K., Kimura, G., Kimura, K., Kitaoka, H., Kobayashi, S., Kohara, K., Kojima, S., Komuro, I., Kumagai, H., Kumagai, Y., Kusano, E., Kushiro, T., Kuwajima, I., Maruyama, Y., Masani, F., Matsubara, H., Matsubara, T., Matsumoto, M., Matsuoka, H., Matsuura, H., Mishima, Y., Miura, M., Miyamori, I., Mori, H., Murakami, H., Muratani, H., Nakagawa, M., Nakao, K., Naruse, M., Nishio, I., Ogihara, T., Ohta, M., Ohtsuka, K., Ohtsuka, Y., Ohuchi, Y., Oikawa, S., Okabe, M., Okumura, K., Saitoh, I., Saitoh, H., Sakata, T., Saku, K., Sasaki, H., Seino, M., Senda, S., Shimada, K., Shimamoto, K., Shimizu, M., Shiomi, T., Shirato, K., Sone, M., Suzuki, H., Suzuki, S., Takahashi, H., Takada, M., Takeda, K., Takeda, N., Takeshita, A., Takishita, S., Tanaka, S., Toba, K., Tochikubo, O., Tomoike, H., Ueno, Y., Umemura, S., Urata, H., Watanabe, T., Yamada, K., Yamaguchi, T., Yamakado, M., Yamamoto, Y., Yamamoto, Y., Yamashina, A., Yokoyama, H., Yoshimura, M., Satoh, H., Oka, Y., Katagiri, H., Kondo, Y., Shishido, H., Kohinata, A., Kanno, Y., Ikeda, H., Takahira, Y., Takahashi, T., Kimura, A., Funahashi, J., Takada, N., Hanazawa, T., Suzuki, N., Osugi, M., Hashimoto, J., Ogawa, Y., Miyamura, T., Masuda, Y., Tanaka, S., Tanaka, S., Koizumi, M., Ando, T., Endo, T., Tsuchida, A., Nanba, M., Yonekura, S., Shiroishi, M., Nakagawa, M., Ito, K., Oda, K., Takahashi, K., Kanahara, I., Hirota, N., Tsutsui, M., Anzai, J., Hosoda, S., Shiiki, M., Takagawa, Y., Iida, M., Tada, M., Noto, T., Tanaka, H., Tajima, G., Kawamorita, K., Kikuchi, K., Suzuki, H., Suzuki, K., Komai, K., Seki, H., Omoto, A., Takahashi, H., Kitabayashi, A., Kimura, M., Kimura, Y., Yamamoto, H., Takahashi, K., Kimura, H., Kawamorita, Y., Emura, Y., Suzuki, Y., Ishikawa, Y., Nagai, K., Nagai, S., Ito, T., Nihei, K., Yamada, S., Goto, T., Yamamoto, N., Suzuki, Y., Ito, H., Ito, M., Fujita, T., Tominaga, Y., Tominaga, S., Suzuki, K., Ishibashi, K., Ando, Y., Sato, S., Morikawa, H., Kashima, S., Nakayama, D., Hayashi, Y., Ohta, K., Metoki, H., Fukami, K., Hayashi, T., Kishi, M., Tajima, J., Seino, J., Hoshi, H., Imai, Y., Kimura, H., Mori, R., Matsuo, K., Tanno, Y., Shibasaki, A., Yamagishi, T., Ohtomo, E., Ohtsuka, Y., Sasaki, S., Seino, M., Kurosawa, K., Ito, K., Takagi, Y., Kyogoku, S., Ito, K., Ono, Y., Watanabe, M., Watanabe, S., Hiwatashi, N., Yagi, C., Unakami, H., Asayama, K., Mouri, T., Watanabe, T., Kikuchi, K., Maruyama, N., Sone, M., Iwamoto, M., Naganuma, S., Mashiko, H., Ishii, H., Takaya, Y., Kamimoto, M., Shirai, A., Watanabe, R., Tohyama, Y., Araki, F., Sakuma, H., Amada, Y., Sato, E., Techigawara, M., Nakamura, K., Nakayama, T., Hasegawa, K., Hasegawa, K., Nagao, T., Minami, J., Kumagai, Y., Cho, T., Okamoto, K., Iguchi, T., Honzawa, T., Koitabashi, T., Yamada, T., Horikoshi, H., Nagao, T., Yoshimatsu, H., Seki, K., Akiyama, N., Suga, H., Matsunaga, R., Sinozaki, T., Ishimaru, Y., Yagi, N., Takikawa, H., Hukutome, T., Nakajima, C., Sato, H., Simizu, J., Arai, M., Koide, H., Takada, H., Sato, T., Umezu, T., Aoki, H., Nakamoto, H., Komahashi, K., Sekiya, S., Sugimoto, H., Arai, T., Suzuki, H., Inokuma, S., Funazaki, T., Yasuda, F., Kanouzawa, S., Yokota, C., Noguchi, Y., Hatano, M., Izumida, T., Hara, T., Muranaka, H., Suzuki, M., Ogawa, Y., Yabumoto, E., Matsushita, S., Kohzu, K., Sasaki, F., Hata, N., Yanagisawa, M., Ueda, T., Kurosawa, M., Doutare, S., Higashi, S., Kato, M., Hoshino, T., Fukuda, K., Ohtsuki, K., Ikeda, T., Kasatani, T., Yamada, T., Yatagai, S., Ohsuga, E., Yamakado, M., Kawamura, H., Mitsubayashi, H., Yamashina, S., Yamazaki, J., Nanjo, S., Ito, S., Teramoto, T., Gomi, T., Kato, S., Koekawa, N., Kuwaki, K., Ikeda, T., Hori, K., Arai, S., Koyama, H., Ichikawa, M., Hashimoto, A., Mori, H., Abe, S., Ohba, Y., Kurata, F., Miyakawa, M., Kimura, K., Hatori, Y., Ushiyama, M., Yamamoto, H., Adachi, M., Takayama, K., Shimizu, M., Iida, T., Asato, S., Uchiba, K., Watanabe, N., Kotani, M., Akaoka, F., Takahashi, S., Hirahara, K., Suzuki, S., Yamaguchi, Y., Ishikawa, S., Sasaki, K., Terada, Y., Ohhashi, S., Sakamaki, A., Hifumi, N., Ohno, T., Saeki, T., Suzaki, Y., Yamamoto, H., Nakagawa, T., Tomoda, F., Nishino, H., Ise, T., Takakuwa, H., Yokoyama, H., Kitakawa, S., Takasawa, K., Ohkura, T., Yamamoto, Y., Satake, K., Arai, Y., Nakayama, H., Sugiyama, S., Sugiura, K., Yokoyama, M., Ito, A., Okazaki, K., Saito, R., Mihara, J., Naito, A., Takahira, Y., Mori, T., Watanabe, M., Asai, S., Nojiri, O., Sakakura, K., Kozuka, M., Oyama, Y., Kawamura, Y., Inoko, T., Takeuchi, N., Tatematsu, H., Hayakawa, Y., Adachi, N., Tamagaki, N., Nakamura, T., Fukui, A., Amenomori, M., Kanaya, T., Masui, A., Hayashi, K., Nishi, S., Amari, M., Yoshida, K., Matsushita, Y., Sawada, S., Fujiwara, M., Ono, S., Tamai, K., Takemoto, Y., Kanemasa, T., Takenaka, T., Kitayama, K., Yasui, K., Fujita, S., Terayama, Y., Kato, N., Nagai, M., Takashima, H., Watanabe, K., Hirobe, N., Miyamoto, M., Sakamoto, N., Kurimoto, Y., Suzuki, N., Katsuya, S., Katsuya, T., Nagao, K., Nakamuta, K., Goto, S., Ueda, T., Imai, N., Sano, I., Ueda, H., Takahashi, N., Sada, T., Iwane, M., Suzuki, H., Yoshikawa, H., Tominaga, Y., Kamura, M., Ohtahara, A., Nakamura, Y., Osakada, M., Gen, M., Kahara, M., Yoshimoto, T., Mizuno, K., Furukawa, Y., Tokunaga, A., Sasaki, N., Matsumura, M., Furue, T., Iwasaki, K., Ichiki, K., Mizofuchi, S., Yokoi, T., Furumoto, W., Fukui, T., Fujino, K., Ohta, A., Ueda, S., Kitami, Y., Ohkura, T., Takeuchi, M., Yoshida, K., Nishiyama, S., Kawamoto, R., Kobaru, A., Endo, T., Kitano, K., Hirooka, Y., Tohaya, M., Miyazaki, Y., Onoyama, K., Miyagi, J., Kin, U., Fujishima, Y., Kuwahara, A., Shindo, R., Satake, Y., Moritsuka, T., Kuwahara, T., Hano, O., Takagi, Y., Suzuki, S., Abe, K., Sato, T., Kohno, M., Fujino, T., Wakayama, K., Aso, T., Goto, T., Ozaki, H., Ninomiya, K., Inobe, Y., Hamasaki, S., Inoue, J., Naomi, S., Iwaoka, T., Ono, T., Muta, Y., Endo, Y., Ohmori, H., Nagata, M., Wake, N., Kozawa, H., Tomino, Y., Ikeda, T., Yoshii, H., Nakamura, H., Fujimoto, N., Asato, T., Tozawa, M., Sunagawa, R., Nakamura, Y., Tomori, H. & Takashiba, K., 2007, In: Clinical and Experimental Hypertension. 29, 1, p. 69-81 13 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig

Radhakrishnan, A., Ikeda, Y., Hyock, J. K., Brown, M. S. & Goldstein, J. L., Apr 17 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 16, p. 6511-6518 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

479 Scopus citations

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins

Sun, L. P., Seemann, J., Goldstein, J. L. & Brown, M. S., Apr 17 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 16, p. 6519-6526 8 p.

Research output: Contribution to journal › Article › peer-review

243 Scopus citations

The development of hypocretin (OREXIN) deficiency in hypocretin/ataxin-3 transgenic rats

Zhang, S., Lin, L., Kaur, S., Thankachan, S., Blanco-Centurion, C., Yanagisawa, M., Mignot, E. & Shiromani, P. J., Aug 10 2007, In: Neuroscience. 148, 1, p. 34-43 10 p.

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Ufd1 Is a Cofactor of gp78 and Plays a Key Role in Cholesterol Metabolism by Regulating the Stability of HMG-CoA Reductase

Cao, J., Wang, J., Qi, W., Miao, H. H., Wang, J., Ge, L., DeBose-Boyd, R. A., Tang, J. J., Li, B. L. & Song, B. L., Aug 8 2007, In: Cell Metabolism. 6, 2, p. 115-128 14 p.

Research output: Contribution to journal › Article › peer-review

78 Scopus citations

Vigilance state-dependent attenuation of hypercapnic chemoreflex and exaggerated sleep apnea in orexin knockout mice

Nakamura, A., Zhang, W., Yanagisawa, M., Fukuda, Y. & Kuwaki, T., Jan 2007, In: Journal of applied physiology. 102, 1, p. 241-248 8 p.

Research output: Contribution to journal › Article › peer-review

137 Scopus citations

2006

A 15-ketosterol is a liver X receptor ligand that suppresses sterol-responsive element binding protein-2 activity

Schmidt, R. J., Ficorilli, J. V., Zhang, Y., Bramlett, K. S., Beyer, T. P., Borchert, K., Dowless, M. S., Houck, K. A., Burris, T. P., Eacho, P. I., Liang, G., Guo, L. W., Wilson, W. K., Michael, L. F. & Cao, G., May 2006, In: Journal of lipid research. 47, 5, p. 1037-1044 8 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Alteration of Rb binding to HPV 18 E7 modified by transglutaminase 2 with different type of polyamines

Jeon, J. H., Cho, S. Y., Kim, C. W., Shin, D. M., Jang, G. Y., Lee, H. J., Kang, H. S., Park, S. C. & Kim, I. G., 2006, In: Frontiers in Bioscience. 11, 2 P.1199-1590, p. 1540-1548 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice

Takayasu, S., Sakurai, T., Iwasaki, S., Teranishi, H., Yamanaka, A., Williams, S. C., Iguchi, H., Kawasawa, Y. I., Ikeda, Y., Sakakibara, I., Ohno, K., Ioka, R. X., Murakami, S., Dohmae, N., Xie, J., Suda, T., Motoike, T., Ohuchi, T., Yanagisawa, M. & Sakai, J., May 9 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 19, p. 7438-7443 6 p.

Research output: Contribution to journal › Article › peer-review

152 Scopus citations

Colorimetric transglutaminase assays combined with immunological signal amplification

Jeon, J. H., Kim, C. W., Shin, D. M., Cho, S. Y., Jang, G. Y., Lee, H. J. & Kim, I. G., Jan 15 2006, In: Analytical biochemistry. 348, 2, p. 327-329 3 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Deletion of endothelial cell endothelin B receptors does not affect blood pressure or sensitivity to salt

Bagnall, A. J., Kelland, N. F., Gulliver-Sloan, F., Davenport, A. P., Gray, G. A., Yanagisawa, M., Webb, D. J. & Kotelevtsev, Y. V., Aug 2006, In: Hypertension. 48, 2, p. 286-293 8 p.

Research output: Contribution to journal › Article › peer-review

84 Scopus citations

Diabetic endothelin B receptor-deficient rats develop severe hypertension and progressive renal failure

Pfab, T., Thöne-Reineke, C., Theilig, F., Lange, I., Witt, H., Maser-Gluth, C., Bader, M., Stasch, J. P., Ruiz, P., Bachmann, S., Yanagisawa, M. & Hocher, B., Apr 2006, In: Journal of the American Society of Nephrology. 17, 4, p. 1082-1089 8 p.

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Direct involvement of orexinergic systems in the activation of the mesolimbic dopamine pathway and related behaviors induced by morphine

Narita, M., Nagumo, Y., Hashimoto, S., Narita, M., Khotib, J., Miyatake, M., Sakurai, T., Yanagisawa, M., Nakamachi, T., Shioda, S. & Suzuki, T., Jan 11 2006, In: Journal of Neuroscience. 26, 2, p. 398-405 8 p.

Research output: Contribution to journal › Article › peer-review

458 Scopus citations

Distribution of neuropeptide W immunoreactivity and mRNA in adult rat brain

Kitamura, Y., Tanaka, H., Motoike, T., Ishii, M., Williams, S. C., Yanagisawa, M. & Sakurai, T., Jun 6 2006, In: Brain Research. 1093, 1, p. 123-134 12 p.

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Hemorheological abnormalities in lipoprotein lipase deficient mice with severe hypertriglyceridemia

Zhao, T., Guo, J., Li, H., Huang, W., Xian, X., Ross, C. J. D., Hayden, M. R., Wen, Z. & Liu, G., Mar 24 2006, In: Biochemical and Biophysical Research Communications. 341, 4, p. 1066-1071 6 p.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Insig-dependent ubiquitination and degradation of 3-hydroxy-3- methylglutaryl coenzyme A reductase stimulated by δ- and γ-tocotrienols

Song, B. L. & DeBose-Boyd, R. A., Sep 1 2006, In: Journal of Biological Chemistry. 281, 35, p. 25054-25061 8 p.

Research output: Contribution to journal › Article › peer-review

165 Scopus citations

Juxtamembranous aspartic acid in Insig-1 and Insig-2 is required for cholesterol homeostasis

Gong, Y., Lee, J. N., Brown, M. S., Goldstein, J. L. & Ye, J., Apr 18 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 16, p. 6154-6159 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

40 Scopus citations

Proteasomal degradation of ubiquitinated Insig proteins is determined by serine residues flanking ubiquitinated lysines

Lee, J. N., Gong, Y., Zhang, X. & Ye, J., Mar 28 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 13, p. 4958-4963 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Reduced expression of the endothelin receptor type B gene in piebald mice caused by insertion of a retroposon-like element in intron 1

Yamada, T., Ohtani, S., Sakurai, T., Tsuji, T., Kunieda, T. & Yanagisawa, M., Apr 21 2006, In: Journal of Biological Chemistry. 281, 16, p. 10799-10807 9 p.

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Research of L-type Ca2+ channel current in atrial myocytes of patients with chronic atrial fibrillation

Li, M. L., Zeng, X. R., Yang, Y., Liu, Z. F., Zhou, W., Ding, Y. Y. & Pei, J., Apr 2006, In: Zhonghua xin xue guan bing za zhi [Chinese journal of cardiovascular diseases]. 34, 4, p. 308-311 4 p.

Research output: Contribution to journal › Article › peer-review

Molecular Genetics

Research output

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