Molecular motion at the critical point in lipid membranes

Harden McConnell, Arun Radhakrishnan

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


It is shown that the calculated temperature dependence of the deuterium nuclear magnetic resonance (NMR) of labeled cholesterol-phospholipid bilayers is changed by magic-angle spinning. This makes it possible to distinguish different molecular motions at temperatures near a miscibility critical point, for motions with distinct temperature-dependent correlation times. In this way one finds that NMR line broadening due to critical point composition fluctuations can be distinguished from broadening due to the formation and dissociation of complexes.

Original languageEnglish (US)
Pages (from-to)L22-L24
JournalBiophysical journal
Issue number2
StatePublished - Jul 15 2008

ASJC Scopus subject areas

  • Biophysics


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