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  • 2013

    XEGFR-mediated beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance

    Wei, Y., Zou, Z., Becker, N., Anderson, M., Sumpter, R., Xiao, G., Kinch, L., Koduru, P., Christudass, C. S., Veltri, R. W., Grishin, N. V., Peyton, M., Minna, J., Bhagat, G. & Levine, B., Sep 12 2013, In: Cell. 154, 6, p. 1269 1 p.

    Research output: Contribution to journal › Article › peer-review

    431 Scopus citations

  • XSystematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer

    Kim, H. S., Mendiratta, S., Kim, J., Pecot, C. V., Larsen, J. E., Zubovych, I., Seo, B. Y., Kim, J., Eskiocak, B., Chung, H., McMillan, E., Wu, S., De Brabander, J., Komurov, K., Toombs, J. E., Wei, S., Peyton, M., Williams, N., Gazdar, A. F., Posner, B. A., & 6 othersBrekken, R. A., Sood, A. K., Deberardinis, R. J., Roth, M. G., Minna, J. D. & White, M. A., Oct 24 2013, In: Cell. 155, 3, p. 552 1 p.

    Research output: Contribution to journal › Article › peer-review

    139 Scopus citations
  • 2012

    An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis

    Huang, X., Dong, Y., Bey, E. A., Kilgore, J. A., Bair, J. S., Li, L. S., Patel, M., Parkinson, E. I., Wang, Y., Williams, N. S., Gao, J., Hergenrother, P. J. & Boothman, D. A., Jun 15 2012, In: Cancer research. 72, 12, p. 3038-3047 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    119 Scopus citations

  • Antitumor activity of a novel STAT3 inhibitor and redox modulator in non-small cell lung cancer cells

    Liu, X., Guo, W., Wu, S., Wang, L., Wang, J., Dai, B., Kim, E. S., Heymach, J. V., Wang, M., Girard, L., Minna, J., Roth, J. A., Swisher, S. G. & Fang, B., May 15 2012, In: Biochemical Pharmacology. 83, 10, p. 1456-1464 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    29 Scopus citations

  • Comparing statistical methods for constructing large scale gene networks

    Allen, J. D., Xie, Y., Chen, M., Girard, L. & Xiao, G., Jan 17 2012, In: PloS one. 7, 1, e29348.

    Research output: Contribution to journal › Article › peer-review

    139 Scopus citations

  • Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

    Rudin, C. M., Durinck, S., Stawiski, E. W., Poirier, J. T., Modrusan, Z., Shames, D. S., Bergbower, E. A., Guan, Y., Shin, J., Guillory, J., Rivers, C. S., Foo, C. K., Bhatt, D., Stinson, J., Gnad, F., Haverty, P. M., Gentleman, R., Chaudhuri, S., Janakiraman, V., Jaiswal, B. S., & 17 othersParikh, C., Yuan, W., Zhang, Z., Koeppen, H., Wu, T. D., Stern, H. M., Yauch, R. L., Huffman, K. E., Paskulin, D. D., Illei, P. B., Varella-Garcia, M., Gazdar, A. F., De Sauvage, F. J., Bourgon, R., Minna, J. D., Brock, M. V. & Seshagiri, S., Oct 2012, In: Nature genetics. 44, 10, p. 1111-1116 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    842 Scopus citations

  • Defining molecular and cellular responses after low and high linear energy transfer radiations to develop biomarkers of carcinogenic risk or therapeutic outcome

    Story, M., Ding, L. H., Brock, W. A., Ang, K. K., Alsbeih, G., Minna, J., Park, S. & Das, A., Nov 2012, In: Health Physics. 103, 5, p. 596-606 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • Differential response of cancer cells to HDAC inhibitors trichostatin A and depsipeptide

    Chang, J., Varghese, D. S., Gillam, M. C., Peyton, M., Modi, B., Schiltz, R. L., Girard, L. & Martinez, E. D., Jan 3 2012, In: British journal of cancer. 106, 1, p. 116-125 10 p.

    Research output: Contribution to journal › Article › peer-review

    84 Scopus citations

  • Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development

    Lockwood, W. W., Wilson, I. M., Coe, B. P., Chari, R., Pikor, L. A., Thu, K. L., Solis, L. M., Nunez, M. I., Behrens, C., Yee, J., English, J., Murray, N., Tsao, M. S., Minna, J. D., Gazdar, A. F., Wistuba, I. I., MacAulay, C. E., Lam, S. & Lam, W. L., May 21 2012, In: PloS one. 7, 5, e37775.

    Research output: Contribution to journal › Article › peer-review

    52 Scopus citations

  • Effect of KRAS oncogene substitutions on protein behavior: Implications for signaling and clinical outcome

    Ihle, N. T., Byers, L. A., Kim, E. S., Saintigny, P., Lee, J. J., Blumenschein, G. R., Tsao, A., Liu, S., Larsen, J. E., Wang, J., Diao, L., Coombes, K. R., Chen, L., Zhang, S., Abdelmelek, M. F., Tang, X., Papadimitrakopoulou, V., Minna, J. D., Lippman, S. M., Hong, W. K., & 4 othersHerbst, R. S., Wistuba, I. I., Heymach, J. V. & Powis, G., Feb 8 2012, In: Journal of the National Cancer Institute. 104, 3, p. 228-239 12 p.

    Research output: Contribution to journal › Article › peer-review

    395 Scopus citations

  • Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus

    James, M. A., Wen, W., Wang, Y., Byers, L. A., Heymach, J. V., Coombes, K. R., Girard, L., Minna, J. & You, M., Jun 4 2012, In: PloS one. 7, 6, e36116.

    Research output: Contribution to journal › Article › peer-review

    83 Scopus citations

  • Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events

    Liu, J., Lee, W., Jiang, Z., Chen, Z., Jhunjhunwala, S., Haverty, P. M., Gnad, F., Guan, Y., Gilbert, H. N., Stinson, J., Klijn, C., Guillory, J., Bhatt, D., Vartanian, S., Walter, K., Chan, J., Holcomb, T., Dijkgraaf, P., Johnson, S., Koeman, J., & 14 othersMinna, J. D., Gazdar, A. F., Stern, H. M., Hoeflich, K. P., Wu, T. D., Settleman, J., De Sauvage, F. J., Gentleman, R. C., Neve, R. M., Stokoe, D., Modrusan, Z., Seshagiri, S., Shames, D. S. & Zhang, Z., Dec 2012, In: Genome Research. 22, 12, p. 2315-2327 13 p.

    Research output: Contribution to journal › Article › peer-review

    167 Scopus citations

  • Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression

    Selamat, S. A., Chung, B. S., Girard, L., Zhang, W., Zhang, Y., Campan, M., Siegmund, K. D., Koss, M. N., Hagen, J. A., Lam, W. L., Lam, S., Gazdar, A. F. & Laird-Offringa, I. A., Jul 2012, In: Genome Research. 22, 7, p. 1197-1211 15 p.

    Research output: Contribution to journal › Article › peer-review

    405 Scopus citations

  • Global evaluation of Eph receptors and ephrins in lung adenocarcinomas identifies EphA4 as an inhibitor of cell migration and invasion

    Saintigny, P., Peng, S., Zhang, L., Sen, B., Wistuba, I. I., Lippman, S. M., Girard, L., Minna, J. D., Heymach, J. V. & Johnson, F. M., Sep 2012, In: Molecular Cancer Therapeutics. 11, 9, p. 2021-2032 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    52 Scopus citations

  • miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers

    Du, L., Subauste, M. C., DeSevo, C., Zhao, Z., Baker, M., Borkowski, R., Schageman, J. J., Greer, R., Yang, C. R., Suraokar, M., Wistuba, I. I., Gazdar, A. F., Minna, J. D. & Pertsemlidis, A., Jun 18 2012, In: PloS one. 7, 6, e39167.

    Research output: Contribution to journal › Article › peer-review

    97 Scopus citations

  • Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer

    Sunaga, N., Imai, H., Shimizu, K., Shames, D. S., Kakegawa, S., Girard, L., Sato, M., Kaira, K., Ishizuka, T., Gazdar, A. F., Minna, J. D. & Mori, M., Apr 15 2012, In: International Journal of Cancer. 130, 8, p. 1733-1744 12 p.

    Research output: Contribution to journal › Article › peer-review

    75 Scopus citations

  • Potential application of non-small cell lung cancer-associated autoantibodies to early cancer diagnosis

    Yao, Y., Fan, Y., Wu, J., Wan, H., Wang, J., Lam, S., Lam, W. L., Girard, L., Gazdar, A. F., Wu, Z. & Zhou, Q., Jul 6 2012, In: Biochemical and Biophysical Research Communications. 423, 3, p. 613-619 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    43 Scopus citations

  • Predictors of survival in never-smokers with non-small cell lung cancer: A large-scale, two-phase genetic study

    Pu, X., Ye, Y., Spitz, M. R., Wang, L., Gu, J., Lippman, S. M., Hildebrandt, M. A. T., Hong, W. K., Minna, J. D., Roth, J. A., Yang, P. & Wu, X., Nov 1 2012, In: Clinical Cancer Research. 18, 21, p. 5983-5991 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • Probe mapping across multiple microarray platforms

    Allen, J. D., Wang, S., Chen, M., Girard, L., Minna, J. D., Xie, Y. & Xiao, G., Sep 2012, In: Briefings in Bioinformatics. 13, 5, p. 547-554 8 p., bbr076.

    Research output: Contribution to journal › Article › peer-review

    24 Scopus citations

  • Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1

    Byers, L. A., Wang, J., Nilsson, M. B., Fujimoto, J., Saintigny, P., Yordy, J., Giri, U., Peyton, M., Fan, Y. H., Diao, L., Masrorpour, F., Shen, L., Liu, W., Duchemann, B., Tumula, P., Bhardwaj, V., Welsh, J., Weber, S., Glisson, B. S., Kalhor, N., & 8 othersWistuba, I. I., Girard, L., Lippman, S. M., Mills, G. B., Coombes, K. R., Weinstein, J. N., Minna, J. D. & Heymach, J. V., Sep 2012, In: Cancer discovery. 2, 9, p. 798-811 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    409 Scopus citations

  • Research resource: Diagnostic and therapeutic potential of nuclear receptor expression in lung cancer

    Jeong, Y., Xie, Y., Lee, W., Bookout, A. L., Girard, L., Raso, G., Behrens, C., Wistuba, I. I., Gadzar, A. F., Minna, J. D. & Mangelsdorf, D. J., Aug 1 2012, In: Molecular Endocrinology. 26, 8, p. 1443-1454 12 p.

    Research output: Contribution to journal › Article › peer-review

    39 Scopus citations

  • The circadian clock gene BMAL1 is a novel therapeutic target for malignant pleural mesothelioma

    Elshazley, M., Sato, M., Hase, T., Yamashita, R., Yoshida, K., Toyokuni, S., Ishiguro, F., Osada, H., Sekido, Y., Yokoi, K., Usami, N., Shames, D. S., Kondo, M., Gazdar, A. F., Minna, J. D. & Hasegawa, Y., Dec 15 2012, In: International Journal of Cancer. 131, 12, p. 2820-2831 12 p.

    Research output: Contribution to journal › Article › peer-review

    65 Scopus citations

  • The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA

    Rabellino, A., Carter, B., Konstantinidou, G., Wu, S. Y., Rimessi, A., Byers, L. A., Heymach, J. V., Girard, L., Chiang, C. M., Teruya-Feldstein, J. & Scaglioni, P. P., May 1 2012, In: Cancer research. 72, 9, p. 2275-2284 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    91 Scopus citations

  • Transient but not stable ZEB1 knockdown dramatically inhibits growth of malignant pleural mesothelioma cells

    Horio, M., Sato, M., Takeyama, Y., Elshazley, M., Yamashita, R., Hase, T., Yoshida, K., Usami, N., Yokoi, K., Sekido, Y., Kondo, M., Toyokuni, S., Gazdar, A. F., Minna, J. D. & Hasegawa, Y., Jul 2012, In: Annals of Surgical Oncology. 19, SUPPL. 3, p. S634-S645

    Research output: Contribution to journal › Article › peer-review

    Open Access
    6 Scopus citations
  • 2011

    A five-gene and corresponding protein signature for stage-I lung adenocarcinoma prognosis

    Kadara, H., Behrens, C., Yuan, P., Solis, L., Liu, D., Gu, X., Minna, J. D., Lee, J. J., Kim, E., Hong, W. K., Wistuba, I. I. & Lotan, R., Mar 15 2011, In: Clinical Cancer Research. 17, 6, p. 1490-1501 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    62 Scopus citations

  • A long AAAG repeat allele in the 5′ UTR of the ERR-γ gene is correlated with breast cancer predisposition and drives promoter activity in MCF-7 breast cancer cells

    Galindo, C. L., McCormick, J. F., Bubb, V. J., Abid Alkadem, D. H., Li, L. S., McIver, L. J., George, A. C., Boothman, D. A., Quinn, J. P., Skinner, M. A. & Garner, H. R., Nov 2011, In: Breast Cancer Research and Treatment. 130, 1, p. 41-48 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • Cells lacking IKKα show nuclear cyclin D1 overexpression and a neoplastic phenotype: Role of IKKα as a tumor suppressor

    Kwak, Y. T., Radaideh, S. M., Ding, L., Li, R., Frenkel, E., Story, M. D., Girard, L., Minna, J. & Verma, U. N., Mar 2011, In: Molecular Cancer Research. 9, 3, p. 341-349 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    21 Scopus citations

  • Enhancing the potency of a whole-cell breast cancer vaccine in mice with an antibody-IL-2 immunocytokine that targets exposed phosphatidylserine

    Huang, X., Ye, D. & Thorpe, P. E., Jun 24 2011, In: Vaccine. 29, 29-30, p. 4785-4793 9 p.

    Research output: Contribution to journal › Article › peer-review

    28 Scopus citations

  • Evolving concepts in lung carcinogenesis

    Gomperts, B. N., Spira, A., Massion, P. P., Walser, T. C., Wistuba, I. I., Minna, J. D. & Dubinett, S. M., 2011, In: Seminars in Respiratory and Critical Care Medicine. 32, 1, p. 32-43 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    56 Scopus citations

  • Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts

    Zhang, Y. A., Maitra, A., Hsieh, J. T., Rudin, C. M., Peacock, C. D., Karikari, C., Brekken, R. A., Stastny, V., Gao, B., Girard, L., Wistuba, I., Frenkel, E., Minna, J. D. & Gazdar, A. F., Oct 1 2011, In: Cancer Biology and Therapy. 12, 7, p. 617-628 12 p.

    Research output: Contribution to journal › Article › peer-review

    23 Scopus citations

  • From mice and men to earth and space: Joint NASA-NCI workshop on lung cancer risk resulting from space and terrestrial radiation

    Shay, J. W., Cucinotta, F. A., Sulzman, F. M., Coleman, C. N. & Minna, J. D., Nov 15 2011, In: Cancer research. 71, 22, p. 6926-6929 4 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    24 Scopus citations

  • Genome-wide association study of survival in non-small cell lung cancer patients receiving platinum-based chemotherapy

    Wu, X., Ye, Y., Rosell, R., Amos, C. I., Stewart, D. J., Hildebrandt, M. A. T., Roth, J. A., Minna, J. D., Gu, J., Lin, J., Buch, S. C., Nukui, T., Ramirez Serrano, J. L., Taron, M., Cassidy, A., Lu, C., Chang, J. Y., Lippman, S. M., Hong, W. K., Spitz, M. R., & 2 othersRomkes, M. & Yang, P., May 18 2011, In: Journal of the National Cancer Institute. 103, 10, p. 817-825 9 p.

    Research output: Contribution to journal › Article › peer-review

    83 Scopus citations

  • Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy

    Yang, F., Tang, X., Riquelme, E., Behrens, C., Nilsson, M. B., Giri, U., Varella-Garcia, M., Byers, L. A., Lin, H. Y., Wang, J., Raso, M. G., Girard, L., Coombes, K., Lee, J. J., Herbst, R. S., Minna, J. D., Heymach, J. V. & Wistuba, I. I., Aug 15 2011, In: Cancer research. 71, 16, p. 5512-5521 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    53 Scopus citations

  • Irreparable complex DNA double-strand breaks induce chromosome breakage in organotypic three-dimensional human lung epithelial cell culture

    Asaithamby, A., Hu, B., Delgado, O., Ding, L. H., Story, M. D., Minna, J. D., Shay, J. W. & Chen, D. J., Jul 2011, In: Nucleic acids research. 39, 13, p. 5474-5488 15 p.

    Research output: Contribution to journal › Article › peer-review

    42 Scopus citations

  • Knockdown of oncogenic KRAS in non-small cell lung cancers suppresses tumor growth and sensitizes tumor cells to targeted therapy

    Sunaga, N., Shames, D. S., Girard, L., Peyton, M., Larsen, J. E., Imai, H., Soh, J., Sato, M., Yanagitani, N., Kaira, K., Xie, Y., Gazdar, A. F., Mori, M. & Minna, J. D., Feb 2011, In: Molecular Cancer Therapeutics. 10, 2, p. 336-346 11 p.

    Research output: Contribution to journal › Article › peer-review

    137 Scopus citations

  • Mechanistic contribution of ubiquitous 15-lipoxygenase-1 expression loss in cancer cells to terminal cell differentiation evasion

    Moussalli, M. J., Wu, Y., Zuo, X., Yang, X. L., Wistuba, I. I., Raso, M. G., Morris, J. S., Bowser, J. L., Minna, J. D., Lotan, R. & Shureiqi, I., Dec 2011, In: Cancer Prevention Research. 4, 12, p. 1961-1972 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    35 Scopus citations

  • Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of β-lapachone for pancreatic cancer therapy

    Li, L. S., Bey, E. A., Dong, Y., Meng, J., Patra, B., Yan, J., Xie, X. J., Brekken, R. A., Barnett, C. C., Bornmann, W. G., Gao, J. & Boothman, D. A., Jan 15 2011, In: Clinical Cancer Research. 17, 2, p. 275-285 11 p.

    Research output: Contribution to journal › Article › peer-review

    97 Scopus citations

  • Multipotent capacity of immortalized human bronchial epithelial cells

    Delgado, O., Kaisani, A. A., Spinola, M., Xie, X. J., Batten, K. G., Minna, J. D., Wright, W. E. & Shay, J. W., 2011, In: PloS one. 6, 7, e22023.

    Research output: Contribution to journal › Article › peer-review

    58 Scopus citations

  • Oral iloprost improves endobronchial dysplasia in former smokers

    Keith, R. L., Blatchford, P. J., Kittelson, J., Minna, J. D., Kelly, K., Massion, P. P., Franklin, W. A., Mao, J., Wilson, D. O., Merrick, D. T., Hirsch, F. R., Kennedy, T. C., Bunn, P. A., Geraci, M. W. & Miller, Y. E., Jun 2011, In: Cancer Prevention Research. 4, 6, p. 793-802 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    90 Scopus citations

  • Pivotal role of epithelial cell adhesion molecule in the survival of lung cancer cells

    Hase, T., Sato, M., Yoshida, K., Girard, L., Takeyama, Y., Horio, M., Elshazley, M., Oguri, T., Sekido, Y., Shames, D. S., Gazdar, A. F., Minna, J. D., Kondo, M. & Hasegawa, Y., Aug 2011, In: Cancer Science. 102, 8, p. 1493-1500 8 p.

    Research output: Contribution to journal › Article › peer-review

    24 Scopus citations

  • Robust gene expression signature from formalin-fixed paraffin-embedded samples predicts prognosis of non-small-cell lung cancer patients

    Xie, Y., Xiao, G., Coombes, K. R., Behrens, C., Solis, L. M., Raso, G., Girard, L., Erickson, H. S., Roth, J., Heymach, J. V., Moran, C., Danenberg, K., Minna, J. D. & Wistuba, I. I., Sep 1 2011, In: Clinical Cancer Research. 17, 17, p. 5705-5714 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    128 Scopus citations

  • SMAC mimetic (JP1201) sensitizes non-small cell lung cancers to multiple chemotherapy agents in an IAP-dependent but TNF-α-independent manner

    Greer, R. M., Peyton, M., Larsen, J. E., Girard, L., Xie, Y., Gazdar, A. F., Harran, P., Wang, L., Brekken, R. A., Wang, X. & Minna, J. D., Dec 15 2011, In: Cancer research. 71, 24, p. 7640-7648 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    47 Scopus citations

  • Sporadic breast cancer patients' germline DNA exhibit an AT-rich microsatellite signature

    Galindo, C. L., McIver, L. J., Tae, H., McCormick, J. F., Skinner, M. A., Hoeschele, I., Lewis, C. M., Minna, J. D., Boothman, D. A. & Garner, H. R., Apr 2011, In: Genes Chromosomes and Cancer. 50, 4, p. 275-283 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • STAT3 mediates resistance to MEK inhibitor through microRNA miR-17

    Dai, B., Meng, J., Peyton, M., Girard, L., Bornmann, W. G., Ji, L., Minna, J. D., Fang, B. & Roth, J. A., May 15 2011, In: Cancer research. 71, 10, p. 3658-3668 11 p.

    Research output: Contribution to journal › Article › peer-review

    78 Scopus citations

  • The national lung screening trial: Overview and study design

    Gatsonis, C. A., Aberle, D. R., Berg, C. D., Black, W. C., Church, T. R., Fagerstrom, R. M., Galen, B., Gareen, I. F., Goldin, J., Gohagan, J. K., Hillman, B., Jaffe, C., Kramer, B. S., Lynch, D., Marcus, P. M., Schnall, M., Sullivan, D. C., Sullivan, D., Zylak, C. J., Cagnon, C., & 1,319 othersCody, D., Fletcher, G., Flynn, M. J., Judy, P. F., Kruger, R., Larke, F. J., McNitt-Gray, M., Payne, T., Anthony Seibert, J., Wu, X., Abbott, G., Amorosa, J. K., Barr, R. G., Boiselle, P. M., Chiles, C., Clark, R., Coppage, L., Falk, R., Fishman, E. K., Gemmel, D., Goldin, J. G., Goodman, E., Hart, E. M., Hazelton, T., Johnson, E., Kazerooni, E., McComb, B., McLennan, G., Munden, R. F., Ravenel, J., Sullivan, M., Swensen, S. J., Torigian, D. A., Vydareny, K. H., Worrell, J. A., Balkin, P., Fouad, M., Freedman, M. T., Garg, K., Gelmann, E. P., Gierada, D. S., Hocking, W., Inampudi, S., Isaacs, C., Kvale, P., Mann, H., Manor, W., Nath, H., Reding, D., Spizarny, D. L., Strollo, D. C., Waltz, J., Chen, M. H., Duan, F., Izmirilian, G., Pinsky, P., Prorok, P. C., Miller, A. B., Edelman, M. J., Evans, W. K., Fontana, R. S., Machtay, M., Clark, K. W., Clingan, K. L., Ford, M. B., Márquez, G., Moore, S. M., Ohan, P., Payne, T. J., Peace, S., Rosenbaum, J. L., Barr, R., Black, W., Torigian, D., Vydareny, K., Worrell, J., Young, R. C., Alberts, D., DeMets, D., Greenwald, P., Jacobs, P., McLoud, T. C., Naidich, D. P., Tatum, J., Sausville, E. A., Burke, W., Colice, G., Edwards, B., Emerson, S., Fletcher, J., Green, S., Harris, R., Klein, J. S., Korn, E. L., Mayer, R., Selby, J. V., Sturges, D. W., Turnbull, B. W., Watson, T. J., Baylin, S., Caporaso, N., Dennis, P., Dubinett, S., Franklin, W., Grizzle, W., Hirsch, F., Massion, P., McKeeta-Frobeck, K., Minna, J., Patz, E., Spitz, M., Berg, C. 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    Research output: Contribution to journal › Article › peer-review

    Open Access
    932 Scopus citations
  • 2010

    A catalog of genes homozygously deleted in human lung cancer and the candidacy of PTPRD as a tumor suppressor gene

    Kohno, T., Otsuka, A., Girard, L., Sato, M., Iwakawa, R., Ogiwara, H., Sanchez-Cespedes, M., Minna, J. D. & Yokota, J., Apr 2010, In: Genes Chromosomes and Cancer. 49, 4, p. 342-352 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    70 Scopus citations

  • Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling

    Sullivan, J. P., Spinola, M., Dodge, M., Raso, M. G., Behrens, C., Gao, B., Schuster, K., Shao, C., Larsen, J. E., Sullivan, L. A., Honorio, S., Xie, Y., Scaglioni, P. P., DiMaio, J. M., Gazdar, A. F., Shay, J. W., Wistuba, I. I. & Minna, J. D., Dec 1 2010, In: Cancer research. 70, 23, p. 9937-9948 12 p.

    Research output: Contribution to journal › Article › peer-review

    343 Scopus citations

  • Alternative splicing of caspase 9 is modulated by the phosphoinositide 3-kinase/Akt pathway via phosphorylation of SRp30a

    Shultz, J. C., Goehe, R. W., Wijesinghe, D. S., Murudkar, C., Hawkins, A. J., Shay, J. W., Minna, J. D. & Chalfant, C. E., Nov 15 2010, In: Cancer research. 70, 22, p. 9185-9196 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    114 Scopus citations

  • An orthotopic lung tumor model for image-guided microirradiation in rats

    Saha, D., Watkins, L., Yin, Y., Thorpe, P., Story, M. D., Song, K., Raghavan, P., Timmerman, R., Chen, B., Minna, J. D. & Solberg, T. D., Jul 2010, In: Radiation research. 174, 1, p. 62-71 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations

  • A second genetic variant on chromosome 15q24-25.1 associates with lung cancer

    Liu, P., Yang, P., Wu, X., Vikis, H. G., Lu, Y., Wang, Y., Schwartz, A. G., Pinney, S. M., De Andrade, M., Gazdar, A., Gaba, C., Mandal, D., Lee, J., Kupert, E., Seminara, D., Minna, J., Bailey-Wilson, J. E., Spitz, M., Amos, C. I., Anderson, M. W., & 1 othersYou, M., Apr 15 2010, In: Cancer research. 70, 8, p. 3128-3135 8 p.

    Research output: Contribution to journal › Article › peer-review

    4 Scopus citations