Year in Review 2020: Multisystemic impact of cystic fibrosis

Preeti B. Sharma, Meghana Sathe, Adrienne P. Savant

Research output: Contribution to journalReview articlepeer-review


Clinical care in cystic fibrosis (CF) has continued to advance over the last several years, particularly with the widespread eligibility and use of highly effective modulator therapy. Improved outcomes and longevity of persons with CF (PwCF) have increased recognition of the multisystem impact of the disease on the daily lives of PwCF. This review will cover a broad array of topics, from diagnosis to multisystem effects related to mental health, endocrine, palliative care, reproductive health, otolaryngology, and cardiac issues. Additionally, worldwide care delivery will be reviewed, demonstrating variation in outcomes based on resources and populations served. This review is part of the CF Year in Review 2020 series, focusing on the multi-system effects of CF. This review focuses on articles from Pediatric Pulmonology but also includes articles published in 2020 from other journals that are of particular interest to clinicians.

Original languageEnglish (US)
Pages (from-to)3110-3119
Number of pages10
JournalPediatric pulmonology
Issue number10
StatePublished - Oct 2021


  • International Health
  • cystic fibrosis
  • epidemiology

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine


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