An indexed rotational immobilization system was developed for supine total body irradiation (TBI). Treatment plans had multi-isocentric volumetric modulated arc therapy (VMAT) beams to the upper body and parallelopposed fields to the lower body, with a 12 Gy prescription dose to > 90% of the body and mean lung dose ~8 Gy. In the end-to-end test, point dose measurements had < 10% error. Compared to conventional TBI, the VMAT-based TBI technique increased the mean dose to the body by ~1.0-1.5 Gy and decreased the mean dose to the lung by ~1.0-1.5 Gy. Overall treatment time was ~1.5 h, similar to conventional TBI.
- Immobilization system
- Total body irradiation
- Volumetric modulated arc therapy
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging