Vitreoretinal lymphoma followed by systemic diffuse large B cell lymphoma

Kenneth C. Fan, Kimberly D. Tran, J. William Harbour, Sander A. Dubovy, Nimesh A. Patel, Thomas A. Albini

Research output: Contribution to journalLetterpeer-review

3 Scopus citations


Vitreoretinal lymphoma as the presenting diagnosis in association with a systemic lymphoma without central nervous system involvement is exceedingly rare, and the classification of this condition is not well-established. Here, we describe a patient with intermittent blurry vision in the left eye for 2 years in the setting of a recent incidental diagnosis of diffuse large B cell lymphoma from an axillary lymph node biopsy. The diagnosis of panuveitis with an extensive exudative retinal detachment was made. The patient was treated with pars plana vitrectomy as well as systemic chemotherapy, intrathecal methotrexate, intravitreal methotrexate, and intravitreal rituximab with good post-operative outcomes.

Original languageEnglish (US)
Article number11
JournalJournal of Ophthalmic Inflammation and Infection
Issue number1
StatePublished - Dec 1 2019
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology
  • Infectious Diseases


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