Visualization and quantification of renal R2* changes during water diuresis

Chun S. Zuo, Neil M. Rofsky, Houman Mahallati, Jeongsik Yu, Ming Zhang, Scott Gilbert, Franklin H. Epstein

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Purpose: To refine and evaluate methods for analysis of renal blood oxygenation level dependent (BOLD) MRI data. Materials and Methods: Color R2* maps and regions-of-interest (ROIs) on the borderline between cortex and medulla were applied to renal BOLD MRI data of a group of 13 young female subjects. Results: The distribution of R2* within the kidneys was heterogeneous and the response of human kidneys to water diuresis was patchy. R2* values at the cortico-medullary border region have a smaller variation than in wider cortical or medullary regions and are sensitive to physiological changes produced by water diuresis. Conclusion: These methods provide improved visualization of the regional distribution of R2* and its variations and more precise quantification of the changes in renal R2* produced by water diuresis.

Original languageEnglish (US)
Pages (from-to)676-682
Number of pages7
JournalJournal of Magnetic Resonance Imaging
Issue number6
StatePublished - Jun 1 2003


  • Cortico-medullary borderline
  • Map
  • R2*
  • ROI
  • Tenal oxygenation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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