Aaron Jay Yang, Nitin B. Jain

Research output: Chapter in Book/Report/Conference proceedingChapter


Patients with predominantly lower extremity limb pain may have underlying vascular disease from thrombosis or vascular claudication. The axillary, calf, and femoral veins are common sites of thrombosis and it is important to take into consideration a history of clotting disorders such as Factor V Leiden, antiphospholipid syndrome, protein C or S deficiencies, and antithrombin III deficiency. Symptoms related to vascular claudication may first be noticed with exercise or prolonged walking and may mimic musculoskeletal diseases or symptoms closely resembling neurogenic claudication from spinal stenosis. The goals of the physical examination should be to establish quality and presence of pulses and to identify the presence of bruits, venous disease, signs of ischemia, or presence of an aneurysm.

Original languageEnglish (US)
Title of host publicationPain Medicine
Subtitle of host publicationAn Essential Review
PublisherSpringer International Publishing
Number of pages2
ISBN (Electronic)9783319431338
ISBN (Print)9783319431314
StatePublished - Jan 1 2017
Externally publishedYes


  • Aneurysm
  • Ankle brachial index
  • Auscultation
  • Bruits
  • Buerger’s test
  • Ischemia
  • Thrombosis
  • Vascular claudication
  • Venous disease

ASJC Scopus subject areas

  • Medicine(all)


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