Variable effects of heart rate on phasic and regional left ventricular muscle blood flow in anaesthetized dogs

Gerald D. Buckberg; David E Fixler; Joseph P. Archie; R. Peter Henney; Julien I E Hoffman

doi:10.1093/cvr/9.1.1

Variable effects of heart rate on phasic and regional left ventricular muscle blood flow in anaesthetized dogs

Gerald D. Buckberg, David E Fixler, Joseph P. Archie, R. Peter Henney, Julien I E Hoffman

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Abstract

AUTHORS' SYNOPSIS: Tachycardia to 240 beats/min in anaesthetized dogs increases coronary blood flow while flow in the left ventricular wall remains homogeneous. An arteriovenous fistula causes subendocardial ischaemia at 120 beats/min but pacing to 180 to 210 beats/min increases subendocardial blood flow by increasing diastolic coronary driving pressure per minute.

Original language	English (US)
Pages (from-to)	1-11
Number of pages	11
Journal	Cardiovascular Research
Volume	9
Issue number	1
DOIs	https://doi.org/10.1093/cvr/9.1.1
State	Published - Jan 1975

ASJC Scopus subject areas

Physiology
Cardiology and Cardiovascular Medicine
Physiology (medical)

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10.1093/cvr/9.1.1

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abstract = "AUTHORS' SYNOPSIS: Tachycardia to 240 beats/min in anaesthetized dogs increases coronary blood flow while flow in the left ventricular wall remains homogeneous. An arteriovenous fistula causes subendocardial ischaemia at 120 beats/min but pacing to 180 to 210 beats/min increases subendocardial blood flow by increasing diastolic coronary driving pressure per minute.",

author = "Buckberg, {Gerald D.} and Fixler, {David E} and Archie, {Joseph P.} and Henney, {R. Peter} and Hoffman, {Julien I E}",

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N2 - AUTHORS' SYNOPSIS: Tachycardia to 240 beats/min in anaesthetized dogs increases coronary blood flow while flow in the left ventricular wall remains homogeneous. An arteriovenous fistula causes subendocardial ischaemia at 120 beats/min but pacing to 180 to 210 beats/min increases subendocardial blood flow by increasing diastolic coronary driving pressure per minute.

AB - AUTHORS' SYNOPSIS: Tachycardia to 240 beats/min in anaesthetized dogs increases coronary blood flow while flow in the left ventricular wall remains homogeneous. An arteriovenous fistula causes subendocardial ischaemia at 120 beats/min but pacing to 180 to 210 beats/min increases subendocardial blood flow by increasing diastolic coronary driving pressure per minute.

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Variable effects of heart rate on phasic and regional left ventricular muscle blood flow in anaesthetized dogs

Abstract

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