Vanadium-catalyzed C(sp3)-H fluorination reactions

Ji Bao Xia, Yuyong Ma, Chuo Chen

Research output: Contribution to journalArticlepeer-review

74 Scopus citations


Vanadium(iii) oxide catalyzes the direct fluorination of C(sp3)-H groups with Selectfluor. This reaction is operationally simple. The catalyst and the reaction by-product can be removed easily by filtration. Using this method, a fluorine atom can be introduced to the tertiary position of 1,4-cineole and l-menthone selectively.

Original languageEnglish (US)
Pages (from-to)468-472
Number of pages5
JournalOrganic Chemistry Frontiers
Issue number5
StatePublished - Jul 1 2014

ASJC Scopus subject areas

  • Organic Chemistry


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