Uveitis and desquamating rash of the palms and soles

Roselynn H. Nguyen, Anthony A. Nuara, Pitiporn Suwattee, Clay J. Cockerell, Amit G. Pandya

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Syphilis, a sexually transmitted disease caused by the spirochete Treponema pallidum, can affect nearly every organ system in the body. In particular, skin manifestations of secondary syphilis are common but nonspecific and can be a true masquerader of other skin disorders. Concomitant infection with HIV has been increasing and may cause even more unusual skin presentations. We present a patient with the atypical combination of palmoplantar keratoderma and ocular symptoms that closely resembled reactive arthritis (or ReiterE's syndrome). When evaluating patients with HIV infection, clinicians should maintain a high level of suspicion for syphilis to accurately diagnose and treat this curable but potentially fatal disease.

Original languageEnglish (US)
Pages (from-to)494-495
Number of pages2
JournalAmerican Journal of Dermatopathology
Issue number4
StatePublished - Jun 18 2013


  • Reiter's syndrome
  • human immunodeficiency virus
  • keratoderma
  • reactive arthritis
  • syphilis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dermatology


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