TY - JOUR
T1 - Usefulness of serial radionuclide angiography in predicting cardiac death after coronary artery bypass grafting and comparison with clinical and cardiac catheterization data
AU - Borges-Neto, Salvador
AU - Shaw, Leslee J.
AU - Kesler, Karen
AU - Sell, Timothy
AU - Peterson, Eric D.
AU - Coleman, R. Edward
AU - Jones, Robert H.
PY - 1997/4/1
Y1 - 1997/4/1
N2 - This investigation assesses the prognostic value of radionuclide measurements of cardiac function in patients undergoing coronary artery bypass grafting (CABG). Radionuclide angiograms during exercise and at rest were obtained in 182 patients before (≤30 days), early (≤3 months), and late (≤3 years) after CABG. Cox proportional hazard regression analysis was used to identify independent predictors of 44 cardiac deaths that occurred a median 12 years after bypass. Although the exercise ejection fractions before and early after CABG were significantly related to subsequent cardiac death (chi-square = 10.84, p = 0.001, and chi-square = 7.4, p = 0.006, respectively), the late postoperative exercise ejection fraction was the strongest predictor (chi-square = 13.9, p = 0.0002), contributing above and beyond clinical and catheterization data. These data document the validity of the exercise ejection fraction as an important predictor of cardiac death after CABG and suggest the potential clinical application of serial measurements of the exercise ejection fraction as an important noninvasive adjunct to postoperative evaluation of these patients.
AB - This investigation assesses the prognostic value of radionuclide measurements of cardiac function in patients undergoing coronary artery bypass grafting (CABG). Radionuclide angiograms during exercise and at rest were obtained in 182 patients before (≤30 days), early (≤3 months), and late (≤3 years) after CABG. Cox proportional hazard regression analysis was used to identify independent predictors of 44 cardiac deaths that occurred a median 12 years after bypass. Although the exercise ejection fractions before and early after CABG were significantly related to subsequent cardiac death (chi-square = 10.84, p = 0.001, and chi-square = 7.4, p = 0.006, respectively), the late postoperative exercise ejection fraction was the strongest predictor (chi-square = 13.9, p = 0.0002), contributing above and beyond clinical and catheterization data. These data document the validity of the exercise ejection fraction as an important predictor of cardiac death after CABG and suggest the potential clinical application of serial measurements of the exercise ejection fraction as an important noninvasive adjunct to postoperative evaluation of these patients.
UR - http://www.scopus.com/inward/record.url?scp=0030898307&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030898307&partnerID=8YFLogxK
U2 - 10.1016/S0002-9149(97)00002-7
DO - 10.1016/S0002-9149(97)00002-7
M3 - Article
C2 - 9104893
AN - SCOPUS:0030898307
SN - 0002-9149
VL - 79
SP - 851
EP - 855
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 7
ER -