TY - JOUR
T1 - Use of the Indigo CAT RX aspiration system during percutaneous coronary intervention
AU - Peng, Sydney
AU - Rempakos, Athanasios
AU - Mastrodemos, Olga C.
AU - Rangan, Bavana V.
AU - Alexandrou, Michaella
AU - Allana, Salman
AU - Al-Ogaili, Ahmed
AU - Mutlu, Deniz
AU - Karacsonyi, Judit
AU - Bergstedt, Seth
AU - Khalid, Muhmmad S.
AU - Stanberry, Larissa
AU - Brilakis, Emmanouil S.
N1 - Publisher Copyright:
© 2024 Wiley Periodicals LLC.
PY - 2024/4/1
Y1 - 2024/4/1
N2 - Background: The use of the Indigo CAT RX Aspiration System (Penumbra Inc.) during percutaneous coronary intervention has received limited study. Methods: We retrospectively examined the clinical, angiographic, and procedural characteristics, outcomes, and follow-up of patients who underwent mechanical aspiration thrombectomy with the Indigo CAT RX system (Penumbra Inc.) at a large tertiary care hospital between January 2019 and April 2023. Results: During the study period, 83 patients (85 lesions) underwent thrombectomy with the Indigo CAT RX. Mean patient age was 64.9 ± 14.48 years and 31.2% were women. The most common presentations were ST-segment elevation myocardial infarction (MI) (66.2%) and non-ST-segment elevation MI (26.5%). A final thrombolysis in MI flow grade of 3 and final myocardial blush grade of 3 were achieved in 76% and 46% of the cases, respectively. Technical success was achieved in 88.9% of the cases that included Indigo CAT RX treatment only, compared with 57.1% of the cases that also included manual aspiration. There were no device-related serious adverse events. At 30-day postprocedure, the incidence of major adverse cardiac events (composite of cardiovascular death, recurrent MI, cardiogenic shock, new or worsening New York Heart Association Class IV heart failure, stroke) was 8.5%: 1.3% stroke (postprocedure, in-hospital), 1.3% MI, 6.1% cardiac death, and 7.5% developed cardiogenic shock. Conclusions: Use of the Indigo CAT RX system is associated with high technical success and acceptable risk of complications, including stroke.
AB - Background: The use of the Indigo CAT RX Aspiration System (Penumbra Inc.) during percutaneous coronary intervention has received limited study. Methods: We retrospectively examined the clinical, angiographic, and procedural characteristics, outcomes, and follow-up of patients who underwent mechanical aspiration thrombectomy with the Indigo CAT RX system (Penumbra Inc.) at a large tertiary care hospital between January 2019 and April 2023. Results: During the study period, 83 patients (85 lesions) underwent thrombectomy with the Indigo CAT RX. Mean patient age was 64.9 ± 14.48 years and 31.2% were women. The most common presentations were ST-segment elevation myocardial infarction (MI) (66.2%) and non-ST-segment elevation MI (26.5%). A final thrombolysis in MI flow grade of 3 and final myocardial blush grade of 3 were achieved in 76% and 46% of the cases, respectively. Technical success was achieved in 88.9% of the cases that included Indigo CAT RX treatment only, compared with 57.1% of the cases that also included manual aspiration. There were no device-related serious adverse events. At 30-day postprocedure, the incidence of major adverse cardiac events (composite of cardiovascular death, recurrent MI, cardiogenic shock, new or worsening New York Heart Association Class IV heart failure, stroke) was 8.5%: 1.3% stroke (postprocedure, in-hospital), 1.3% MI, 6.1% cardiac death, and 7.5% developed cardiogenic shock. Conclusions: Use of the Indigo CAT RX system is associated with high technical success and acceptable risk of complications, including stroke.
KW - aspiration thrombectomy
KW - penumbra
KW - percutaneous coronary intervention
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U2 - 10.1002/ccd.30994
DO - 10.1002/ccd.30994
M3 - Article
C2 - 38419416
AN - SCOPUS:85186552307
SN - 1522-1946
VL - 103
SP - 695
EP - 702
JO - Catheterization and Cardiovascular Interventions
JF - Catheterization and Cardiovascular Interventions
IS - 5
ER -