Update in the Percutaneous Management of Coronary Chronic Total Occlusions

Peter Tajti, M. Nicholas Burke, Dimitri Karmpaliotis, Khaldoon Alaswad, Gerald S. Werner, Lorenzo Azzalini, Mauro Carlino, Mitul Patel, Kambis Mashayekhi, Mohaned Egred, Oleg Krestyaninov, Dmitrii Khelimskii, William J. Nicholson, Imre Ungi, Alfredo R. Galassi, Subhash Banerjee, Emmanouil S. Brilakis

Research output: Contribution to journalReview articlepeer-review

81 Scopus citations


Percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs) has been rapidly evolving during recent years. With improvement in equipment and techniques, high success rates can be achieved at experienced centers, although overall success rates remain low. Prospective, randomized-controlled data regarding optimal use and indications for CTO PCI remain limited. CTO PCI should be performed when the anticipated benefit exceeds the potential risk. New high-quality studies of the clinical outcomes and techniques of CTO PCI are needed, as is the expansion of expert centers and operators that can achieve excellent clinical outcomes in this challenging patient and lesion subgroup. In the current review the authors summarize the latest publications in CTO PCI and provide an overview of the current state of the field.

Original languageEnglish (US)
Pages (from-to)615-625
Number of pages11
JournalJACC: Cardiovascular Interventions
Issue number7
StatePublished - Apr 9 2018


  • chronic total occlusion
  • percutaneous coronary intervention
  • stable coronary artery disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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