TY - JOUR
T1 - Unexplained Vision Loss Associated With Intraocular Silicone Oil Tamponade in Rhegmatogenous Retinal Detachment Repair
AU - Pakravan, Parastou
AU - Shaheen, Abdulla
AU - Patel, Veshesh
AU - Villalba, Maria F.
AU - Dib, Bernard
AU - Lai, James
AU - Rohowetz, Landon
AU - Chau, Viet
AU - Patel, Nimesh A.
AU - Tzu, Jonathan H.
AU - Wang, Angeline L.
AU - Alhoyek, Sandra
AU - Scott, Nathan
AU - Samara, Wasim A.
AU - Goduni, Lediana
AU - Jung, Jesse J.
AU - Russell, Jonathan F.
AU - Mantopoulos, Dimosthenis
AU - Hajrasouliha, Amir R.
AU - Savoie, Brian T.
AU - Haddock, Luis J.
AU - Berrocal, Audina M.
AU - Sridhar, Jayanth
AU - West, Matthew R.
AU - Yannuzzi, Nicolas A.
N1 - Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Bascom Palmer Eye Institute received funding from the NIH Core Grant P30EY014801, Department of Defense Grant #W81XWH-13-1-0048, and a Research to Prevent Blindness Unrestricted Grant. Parastou Pakravan and Abdulla Shaheen received funding from the Macula Foundation. The sponsors or funding organizations had no role in the design or conduct of this research.
Publisher Copyright:
© The Author(s) 2023.
PY - 2023/7/1
Y1 - 2023/7/1
N2 - Purpose: To evaluate the visual outcomes with unexplained vision loss during or after silicone oil (SO) tamponade. Methods: This multicenter retrospective case series comprised patients with unexplained vision loss associated with SO tamponade or its removal. Eyes with other clear secondary identifiable causes of vision loss were excluded. Results: Twenty-nine eyes of 28 patients (64% male) were identified. The mean age was 50 ± 13 years (range, 13-78 years). The mean duration of SO tamponade was 148 ± 38 days. Eighteen eyes (62%) developed unexplained vision loss while under SO; 11 (38%) had vision loss after SO removal. The most common optical coherence tomography (OCT) finding was ganglion cell layer (GCL) thinning (55%). Eyes with vision loss after SO removal had a mean logMAR best-corrected visual acuity (BCVA) of 0.6 ± 0.7 (Snellen 20/85) before SO tamponade and 1.2 ± 0.4 (20/340) before SO removal. By the last follow-up after SO removal, the BCVA had improved to 1.1 ± 0.4 (20/235). In eyes with vision loss after SO removal, the BCVA before SO removal was 0.7 ± 0.7 (20/104), which deteriorated to 1.4 ± 0.4 (20/458) 1 month after SO removal. By the last follow-up, the BCVA had improved to 1.0 ± 0.5 (20/219). Conclusions: Unexplained vision loss can occur during SO tamponade or after SO removal. Vision loss was associated with 1000-centistoke and 5000-centistoke oil and occurred in macula-off and macula-on retinal detachments. The duration of tamponade was 3 months or longer in the majority of eyes. Most eyes had GCL thinning on OCT. Gradual visual recovery can occur yet is often incomplete.
AB - Purpose: To evaluate the visual outcomes with unexplained vision loss during or after silicone oil (SO) tamponade. Methods: This multicenter retrospective case series comprised patients with unexplained vision loss associated with SO tamponade or its removal. Eyes with other clear secondary identifiable causes of vision loss were excluded. Results: Twenty-nine eyes of 28 patients (64% male) were identified. The mean age was 50 ± 13 years (range, 13-78 years). The mean duration of SO tamponade was 148 ± 38 days. Eighteen eyes (62%) developed unexplained vision loss while under SO; 11 (38%) had vision loss after SO removal. The most common optical coherence tomography (OCT) finding was ganglion cell layer (GCL) thinning (55%). Eyes with vision loss after SO removal had a mean logMAR best-corrected visual acuity (BCVA) of 0.6 ± 0.7 (Snellen 20/85) before SO tamponade and 1.2 ± 0.4 (20/340) before SO removal. By the last follow-up after SO removal, the BCVA had improved to 1.1 ± 0.4 (20/235). In eyes with vision loss after SO removal, the BCVA before SO removal was 0.7 ± 0.7 (20/104), which deteriorated to 1.4 ± 0.4 (20/458) 1 month after SO removal. By the last follow-up, the BCVA had improved to 1.0 ± 0.5 (20/219). Conclusions: Unexplained vision loss can occur during SO tamponade or after SO removal. Vision loss was associated with 1000-centistoke and 5000-centistoke oil and occurred in macula-off and macula-on retinal detachments. The duration of tamponade was 3 months or longer in the majority of eyes. Most eyes had GCL thinning on OCT. Gradual visual recovery can occur yet is often incomplete.
KW - intraocular silicone oil tamponade
KW - rhegmatogenous retinal detachment repair
KW - unexplained vision loss
UR - http://www.scopus.com/inward/record.url?scp=85162705716&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85162705716&partnerID=8YFLogxK
U2 - 10.1177/24741264231161121
DO - 10.1177/24741264231161121
M3 - Article
C2 - 37927311
AN - SCOPUS:85162705716
SN - 2474-1264
VL - 7
SP - 299
EP - 304
JO - Journal of VitreoRetinal Diseases
JF - Journal of VitreoRetinal Diseases
IS - 4
ER -