Understanding the transition to acute illness: the promise of perioperative genomics.

Aslan T. Turer, Debra A. Schwinn

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Over the last decades, tremendous advances have been made in understanding the genomic basis of a large number of chronic human diseases. Such advances were made possible by studying large numbers of patients over relatively long periods of time. It is increasingly recognized that acute robust stress stimulates pathways activated in chronic disease, facilitating mechanistic studies in much shorter time frames. A new field of molecular medicine, called perioperative genomics, uses robust surgical stress as a perturbation designed to explore such mechanisms. This new field is described briefly below.

Original languageEnglish (US)
Pages (from-to)171-173
Number of pages3
JournalJournal of cardiovascular translational research
Issue number2
StatePublished - Jun 2008

ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Pharmaceutical Science
  • Cardiology and Cardiovascular Medicine
  • Genetics(clinical)


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