Abstract
(Figure Presented) An efficient two-component palladium-catalyzed arylation/cyclization cascade approach toward a variety of N-fused pyrroloheterocycles has been developed. This transformation proceeds via the palladium-catalyzed coupling of aryl halides with propargylic esters or ethers followed by the 5-endo-dig cyclization leading to highly functionalized pyrroloheterocycles in good to excellent yield.
Original language | English (US) |
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Pages (from-to) | 3242-3245 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 12 |
Issue number | 14 |
DOIs | |
State | Published - Jul 16 2010 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry