TY - JOUR
T1 - Trisomy 2, trisomy 20, and del(17p) as sole chromosomal abnormalities in three cases of hepatoblastoma
AU - Tonk, V. S.
AU - Wilson, K. S.
AU - Timmons, C. F.
AU - Schneider, N. R.
PY - 1994/11
Y1 - 1994/11
N2 - Short‐term cultures of three hepatoblastomas were analyzed cytogenetically. Trisomy 2, trisomy 20, and a deletion of 17p were found as the sole abnormalities, yielding the karyotypes 47,XY, + 2; 47,XX, + 20; and 46,XX,del(17)(p12)/46,XX. This is the first reported case of deletion of 17p as the sole chromosomal abnormality in a hepatoblastoma and the first reported case of trisomy 20 without double minute chromosomes as a sole chromosomal abnormality in hepatoblastoma.
AB - Short‐term cultures of three hepatoblastomas were analyzed cytogenetically. Trisomy 2, trisomy 20, and a deletion of 17p were found as the sole abnormalities, yielding the karyotypes 47,XY, + 2; 47,XX, + 20; and 46,XX,del(17)(p12)/46,XX. This is the first reported case of deletion of 17p as the sole chromosomal abnormality in a hepatoblastoma and the first reported case of trisomy 20 without double minute chromosomes as a sole chromosomal abnormality in hepatoblastoma.
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U2 - 10.1002/gcc.2870110309
DO - 10.1002/gcc.2870110309
M3 - Article
C2 - 7530489
AN - SCOPUS:0028132075
SN - 1045-2257
VL - 11
SP - 199
EP - 202
JO - Genes, Chromosomes and Cancer
JF - Genes, Chromosomes and Cancer
IS - 3
ER -