Transposition surgery for internuclear ophthalmoplegia

Niraj R. Nathan, Sean P. Donahue

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Purpose: To report outcomes of an extraocular muscle transposition procedure for surgical correction of internuclear ophthalmoplegia. Methods: Records of patients operated on between January 1999 and May 2011 were reviewed to identify patients treated with an extraocular muscle transposition procedure for internuclear ophthalmoplegia. Indications for this procedure included a known unilateral or bilateral internuclear ophthalmoplegia with a large-angle exotropia, a moderate adduction limitation, and a large-angle exodeviation in primary position. All patients underwent orthoptic evaluation preoperatively and postoperatively. Examination included assessment of subjective complaints, visual acuity, deviation in diagnostic positions of gaze, and limitation of ocular motility. Results: Five patients were identifi ed. The mean reduction in exodeviation at distance after surgery was 59 ± 25 prism diopters, giving a mean percent reduction in exodeviation of 99.6% ± 0.1%. Four of fi ve patients achieved primary position orthotropia at distance; the remaining patient had 2 prism diopters of exodeviation. One patient who had a residual exodeviation after the initial transposition procedure did not have accompanying ipsilateral lateral rectus recession, but achieved orthotropia with a subsequent ipsilateral lateral rectus recession. Conclusion: Transposition surgery is an eff ective option for surgical treatment of patients with internuclear ophthalmoplegia with exodeviation and diplopia when combined with ipsilateral lateral rectus recession.

Original languageEnglish (US)
Pages (from-to)378-381
Number of pages4
JournalJournal of pediatric ophthalmology and strabismus
Issue number6
StatePublished - 2012

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Ophthalmology


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