TY - JOUR
T1 - The use of botulinum toxin type A in children with cerebral palsy
T2 - A retrospective study
AU - Delgado, Mauricio R.
PY - 1999
Y1 - 1999
N2 - The dosage and safety of botulinum toxin type A (BTX-A) treatments in 104 children with cerebral palsy were examined in a retrospective chart review of a 2-year period at Texas Scottish Rite Hospital for Children. Almost all of the BTX-A injections were to the muscles of the lower limbs. The average dose of BTX-A was 8-9 U/kg body weight and the interval between injections averaged 3-5 months. The average total amount of BTX-A injected at a single visit ranged from 146 to 186 U. The safety record for these treatments was excellent, with only 14 adverse events reported in 257 patient injection visits. The most commonly reported adverse event was muscle weakness, which is related to the pharmacology of BTX-A treatment.
AB - The dosage and safety of botulinum toxin type A (BTX-A) treatments in 104 children with cerebral palsy were examined in a retrospective chart review of a 2-year period at Texas Scottish Rite Hospital for Children. Almost all of the BTX-A injections were to the muscles of the lower limbs. The average dose of BTX-A was 8-9 U/kg body weight and the interval between injections averaged 3-5 months. The average total amount of BTX-A injected at a single visit ranged from 146 to 186 U. The safety record for these treatments was excellent, with only 14 adverse events reported in 257 patient injection visits. The most commonly reported adverse event was muscle weakness, which is related to the pharmacology of BTX-A treatment.
KW - Botulinum toxin type A
KW - Cerebral palsy
KW - Retrospective analysis
KW - Safety
UR - http://www.scopus.com/inward/record.url?scp=0033386127&partnerID=8YFLogxK
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U2 - 10.1111/j.1468-1331.1999.tb00026.x
DO - 10.1111/j.1468-1331.1999.tb00026.x
M3 - Article
AN - SCOPUS:0033386127
SN - 1351-5101
VL - 6
SP - s11-s18
JO - European Journal of Neurology
JF - European Journal of Neurology
IS - SUPPL. 4
ER -