The tumor necrosis factors: Cachectin and lymphotoxin

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


The extensive tissue damage associated with endotoxemia and the phenomenon of tumor necrosis are both triggered by cachectin and lymphotoxin - two leukocyte products with potentially toxic effects on virtually every organ system. Understanding the role of these cytokines in the pathogenesis of inflammation may lead to effective therapy for a wide range of diseases.

Original languageEnglish (US)
Pages (from-to)45-56
Number of pages12
JournalHospital Practice
Issue number2
StatePublished - Jan 1 1990

ASJC Scopus subject areas

  • Medicine(all)


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