The role of dopamine and norepinephrine in depression and antidepressant treatment

David J. Nutt, David S. Baldwin, Anita H. Clayton, Rodney Elgie, Yves Lecrubier, Angel L. Montejo, George I. Papakostas, Daniel Souery, Madhukar H. Trivedi, Andre Tylee

Research output: Contribution to journalReview articlepeer-review

35 Scopus citations

Abstract

During a special session, the faculty identified several specific areas related to the role of dopamine and norepinephrine in depression and antidepressant treatment that either warrant the clinician's attention or are in need of more research. Areas of interest include fatigue and lethargy in depression, treatment strategies for treatment-resistant depression, the somatic presentation of depression, neurobiology of fatigue and its role in determining treatment, symptom rating scales, and sexual side effects. In addition, the faculty discussed the importance of patient psychoeducation and self-management as well as the ways in which disease models of depression affect treatment.

Original languageEnglish (US)
Pages (from-to)46-49
Number of pages4
JournalJournal of Clinical Psychiatry
Volume67
Issue numberSUPPL. 6
StatePublished - 2006

ASJC Scopus subject areas

  • Psychiatry and Mental health

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