Abstract
The histories of tumor necrosis factor (TNF) and cachectin have recently converged, with the recognition that they are one and the same molecule. Cachectin/TNF appears to be a major factor in the pathology that accompanies invasion by a foreign organism - the host mounts an exagerated response that is itself debilatory. Here, Bruce Beutler and Anthony Cerami review the involvement of cachectin/TNF in wasting and shock, as well as its more beneficial influences.
Original language | English (US) |
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Pages (from-to) | 28-31 |
Number of pages | 4 |
Journal | Trends in Immunology |
Volume | 9 |
Issue number | 1-12 |
State | Published - 1988 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology