TY - JOUR
T1 - The relation of ulcerative colitis to psychiatric factors
T2 - A review of findings and methods
AU - North, Carol S.
AU - Clouse, Ray E.
AU - Spitznagel, Edward L.
AU - Alpers, David H.
PY - 1990/1/1
Y1 - 1990/1/1
N2 - The authors reviewed all known English-language literature on the association between psychiatric factors and ulcerative colitis to ascertain the evidence for such an association and evaluate the methods used in these studies. Most of the 138 studies contained serious flaws in research design, such as lack of control subjects, unspecified manner of data collection, and absence of diagnostic criteria. Analysis revealed that methodological flaws were significantly related to the finding of a positive association between psychiatric factors and ulcerative colitis. Seven studies represented solid systematic investigation, and all seven failed to find such an association.
AB - The authors reviewed all known English-language literature on the association between psychiatric factors and ulcerative colitis to ascertain the evidence for such an association and evaluate the methods used in these studies. Most of the 138 studies contained serious flaws in research design, such as lack of control subjects, unspecified manner of data collection, and absence of diagnostic criteria. Analysis revealed that methodological flaws were significantly related to the finding of a positive association between psychiatric factors and ulcerative colitis. Seven studies represented solid systematic investigation, and all seven failed to find such an association.
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U2 - 10.1176/ajp.147.8.974
DO - 10.1176/ajp.147.8.974
M3 - Article
C2 - 2197886
AN - SCOPUS:0025106361
SN - 0002-953X
VL - 147
SP - 974
EP - 981
JO - American Journal of Psychiatry
JF - American Journal of Psychiatry
IS - 8
ER -