Endometriozis varligi ve evresinin intrasitoplazmik sperm injeksiyonu ve embriyo transferi uygulanan olgularda klinik gebelik ve bireysel implantasyon hizlarina etkisi

Objective: There is controversy on the detrimental effects of endometriosis on ICSI outcome. The aim of this study is to evaluate the impact of presence and extent of endometriosis on ICSI outcome. Study design: Of 662 consecutive ICSI-ET cycles, 71 had endometriosis. Endometriosis was staged according to the revised American Fertility Society classification at a recent (within one year of ICSI cycle) laparoscopy. Patients were divided into three groups: patients without endometriosis, patients with stage 1-2 endometriosis (minimal-mild disease) and stage 3-4 (moderate-severe disease) endometriosis. Chi-square and one way Anova with Tukey as a post-hoc test were used for statistical analyses. Results: There was no difference in the number of oocytes retrived, fertilization rate, cleavage rate, number of transferred embryos and implantation rates between the three groups. The overall clinical pregnancy rate was 26.1% per transfer and it was similar in women with and without endometriosis (23.9%-26.4%, respectively). Take home baby rates were comparable between the groups as well.