Abstract
The production of dendritic cells, both in-vivo and in-vitro, has become the intense focus of research activities. Common to many of these production protocols is the use of cytokines, typically granulocyte-monocyte colony stimulating factor and either interleukin 4 or tumor necrosis factor alpha or a combination of all three. Herein, we report our findings that a proprietary pinecone extract is capable of in a dose-dependent manner, and in the absence of exogenous cytokines, the rapid differentiation from peripheral blood mononuclear cells of mature CD1a-negative dendritic cells.
Original language | English (US) |
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Pages (from-to) | 209-223 |
Number of pages | 15 |
Journal | International Immunopharmacology |
Volume | 3 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2003 |
Externally published | Yes |
Keywords
- Dendritic cells
- Peripheral blood mononuclear cells
- Pinecone extract
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Pharmacology