TY - JOUR
T1 - The new seventh edition American joint committee on cancer staging of cutaneous non-melanoma skin cancer
T2 - A critical review
AU - Warner, Christina L.
AU - Cockerell, Clay J.
PY - 2011/4/13
Y1 - 2011/4/13
N2 - The seventh edition of the American Joint Committee on Cancer (AJCC) Cancer Staging Manual includes a major revision of the staging protocol for cutaneous carcinomas. There are several significant improvements to the Tumor, Nodes, and Metastases (TNM) staging system, including consideration of high-risk factors within the primary T grade, a decrease in the tumor size threshold from 5cm to 2cm, improved stratification of patient lymph node status, as well as exclusion of Merkel cell carcinomas from the staging system for squamous cell carcinoma (SCC) and other cutaneous carcinomas. However, some important variables in cutaneous SCC were excluded from consideration. In addition, the AJCC Cancer Staging Manual makes some recommendations that will likely prove difficult to apply in clinical practice, particularly that Clark level, depth of invasion, and presence or absence of perineural invasion should be recorded for each peripheral SCC. In this review, we examine the new recommendations with an emphasis on their utility and practicality.
AB - The seventh edition of the American Joint Committee on Cancer (AJCC) Cancer Staging Manual includes a major revision of the staging protocol for cutaneous carcinomas. There are several significant improvements to the Tumor, Nodes, and Metastases (TNM) staging system, including consideration of high-risk factors within the primary T grade, a decrease in the tumor size threshold from 5cm to 2cm, improved stratification of patient lymph node status, as well as exclusion of Merkel cell carcinomas from the staging system for squamous cell carcinoma (SCC) and other cutaneous carcinomas. However, some important variables in cutaneous SCC were excluded from consideration. In addition, the AJCC Cancer Staging Manual makes some recommendations that will likely prove difficult to apply in clinical practice, particularly that Clark level, depth of invasion, and presence or absence of perineural invasion should be recorded for each peripheral SCC. In this review, we examine the new recommendations with an emphasis on their utility and practicality.
KW - Basal-cell-cancer
KW - Keratoacanthoma
KW - Skin-cancer
KW - Squamous-cell-cancer
UR - http://www.scopus.com/inward/record.url?scp=79953802502&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79953802502&partnerID=8YFLogxK
U2 - 10.2165/11539420-000000000-00000
DO - 10.2165/11539420-000000000-00000
M3 - Review article
C2 - 21469759
AN - SCOPUS:79953802502
SN - 1175-0561
VL - 12
SP - 147
EP - 154
JO - American Journal of Clinical Dermatology
JF - American Journal of Clinical Dermatology
IS - 3
ER -