The Metabolic Derangements and Treatment of Diabetic Ketoacidosis

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252 Scopus citations


Diabetic ketoacidosis is a common illness among patients with diabetes. The exact prevalence is unknown, but in one community the rate was estimated to be 13.4 episodes per 1000 patient-years in young persons with diabetes.1 It remains a serious event, with mortality rates as high as 6 to 10 per cent.2, 3 In children under 10 years of age, diabetic ketoacidosis accounts for 70 per cent of diabetes-related deaths.4 Death may be due to derangements that are directly attributable to ketoacidosis, to complications associated with the illness itself, or to abnormalities induced by treatment. Because a substantial percentage of deaths is.

Original languageEnglish (US)
Pages (from-to)159-169
Number of pages11
JournalNew England Journal of Medicine
Issue number3
StatePublished - Jul 21 1983

ASJC Scopus subject areas

  • General Medicine


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