The luxS gene is not required for Borrelia burgdorferi tick colonization, transmission to a mammalian host, or induction of disease

Jon S. Blevins; Andrew T. Revel; Melissa J. Caimano; Xiaofeng F. Yang; James A. Richardson; Kayla E. Hagman; Michael V. Norgard

doi:10.1128/IAI.72.8.4864-4867.2004

The luxS gene is not required for Borrelia burgdorferi tick colonization, transmission to a mammalian host, or induction of disease

Jon S. Blevins, Andrew T. Revel, Melissa J. Caimano, Xiaofeng F. Yang, James A. Richardson, Kayla E. Hagman, Michael V. Norgard

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

luxS mutants of Borrelia burgdorferi strain 297 naturally colonized their arthropod (Ixodes scapularis) vector, were maintained in ticks throughout the molting process (larvae to nymphs), were tick transmitted to uninfected mice, and elicited histopathology in mice indistinguishable from that induced by wild-type B. burgdorferi.

Original language	English (US)
Pages (from-to)	4864-4867
Number of pages	4
Journal	Infection and immunity
Volume	72
Issue number	8
DOIs	https://doi.org/10.1128/IAI.72.8.4864-4867.2004
State	Published - Aug 2004

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

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10.1128/IAI.72.8.4864-4867.2004

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title = "The luxS gene is not required for Borrelia burgdorferi tick colonization, transmission to a mammalian host, or induction of disease",

abstract = "luxS mutants of Borrelia burgdorferi strain 297 naturally colonized their arthropod (Ixodes scapularis) vector, were maintained in ticks throughout the molting process (larvae to nymphs), were tick transmitted to uninfected mice, and elicited histopathology in mice indistinguishable from that induced by wild-type B. burgdorferi.",

author = "Blevins, {Jon S.} and Revel, {Andrew T.} and Caimano, {Melissa J.} and Yang, {Xiaofeng F.} and Richardson, {James A.} and Hagman, {Kayla E.} and Norgard, {Michael V.}",

year = "2004",

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language = "English (US)",

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T1 - The luxS gene is not required for Borrelia burgdorferi tick colonization, transmission to a mammalian host, or induction of disease

AU - Blevins, Jon S.

AU - Revel, Andrew T.

AU - Caimano, Melissa J.

AU - Yang, Xiaofeng F.

AU - Richardson, James A.

AU - Hagman, Kayla E.

AU - Norgard, Michael V.

PY - 2004/8

Y1 - 2004/8

N2 - luxS mutants of Borrelia burgdorferi strain 297 naturally colonized their arthropod (Ixodes scapularis) vector, were maintained in ticks throughout the molting process (larvae to nymphs), were tick transmitted to uninfected mice, and elicited histopathology in mice indistinguishable from that induced by wild-type B. burgdorferi.

AB - luxS mutants of Borrelia burgdorferi strain 297 naturally colonized their arthropod (Ixodes scapularis) vector, were maintained in ticks throughout the molting process (larvae to nymphs), were tick transmitted to uninfected mice, and elicited histopathology in mice indistinguishable from that induced by wild-type B. burgdorferi.

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DO - 10.1128/IAI.72.8.4864-4867.2004

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JO - Infection and immunity

JF - Infection and immunity

IS - 8

ER -

The luxS gene is not required for Borrelia burgdorferi tick colonization, transmission to a mammalian host, or induction of disease

Abstract

ASJC Scopus subject areas

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