The feasibility of endorectal MR elastography for prostate cancer localization

Arvin Arani, Donald Plewes, Axel Krieger, Rajiv Chopra

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


The objectives of this study were to evaluate the feasibility of using a rigid radio-frequency receiver endorectal coil for intracavitary prostate magnetic resonance elastography (MRE) and to demonstrate the capability of this technique for generating stiffness maps over a typical prostate volume. An endorectal coil is currently used to help improve the signal-to-noise ratio of images acquired with multiparametric magnetic resonance imaging. We propose that this same coil could also serve to generate shear waves in the prostate gland during imaging, opening up the possibility of incorporating prostate stiffness characterization into multiparametric magnetic resonance imaging. Prostate cancer has been shown to change the elasticity of tissue, suggesting that stiffness imaging (elastography) may provide supplementary diagnostic information. A rigid endorectal coil was mechanically coupled to a piezoceramic actuator and used to investigate full volume (27 slices, 2-mm thick) endorectal MRE in a prostate mimicking phantom. The low-amplitude vibrations (±8-38 μm displacements) necessary to perform endorectal MRE did not affect the signal-to noise ratio of the coil and endorectal MRE was capable of resolving 0.1cc (0.6 cm diameter) spherical inclusion volumes. Therefore, the results of this study, in combination with current clinical practice, motivate clinical evaluation of endorectal MRE in patients.

Original languageEnglish (US)
Pages (from-to)1649-1657
Number of pages9
JournalMagnetic resonance in medicine
Issue number6
StatePublished - Dec 2011


  • MR elastography
  • cancer
  • endorectal
  • prostate imaging
  • tissue stiffness

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'The feasibility of endorectal MR elastography for prostate cancer localization'. Together they form a unique fingerprint.

Cite this