The effect of protease inhibitors and decreased temperature on the degradation of different classes of proteins in cultured hepatocytes

Medicine & Life Sciences

• leupeptin 91%
• chymostatin 89%
• Protease Inhibitors 87%
• Hepatocytes 71%
• Temperature 60%
• Antipain 53%
• Proteolysis 49%
• Lysosomes 32%
• Proteins 31%
• Fetuins 16%
• Amino Acids 14%
• Cathepsin B 13%
• Cell Extracts 11%
• Glucagon 11%
• Peptide Hydrolases 8%
• Peptides 6%
• Membranes 6%
• Enzymes 5%
• Liver 5%
• Serum 4%

Chemical Compounds

• Protease Inhibitor 100%
• Leupeptin 70%
• Chymostatin 64%
• Protein 35%
• Protein Hydrolysis 16%
• Glucagon 10%
• Polypeptide 6%
• Acid 5%
• Reduction 3%
• Amount 3%