TY - JOUR
T1 - The effect of elevations in internal temperature on event-related potentials during a simple cognitive task in humans
AU - Shibasaki, Manabu
AU - Namba, Mari
AU - Oshiro, Misaki
AU - Crandall, Craig G.
AU - Nakata, Hiroki
N1 - Funding Information:
M. Shibasaki is currently receiving a grant from the Descente and Ishimoto memorial foundation for the promotion of sports science, and H. Nakata from 15H05361 JSPS KAKENHI Grant-in-Aid for young Scientists
Publisher Copyright:
© 2016 the American Physiological Society.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2016/7
Y1 - 2016/7
N2 - The effect of hyperthermia on cognitive function remains equivocal, perhaps because of methodological discrepancy. Using electroencephalographic eventrelated potentials (ERPs), we tested the hypothesis that a passive heat stress impairs cognitive processing. Thirteen volunteers performed repeated auditory oddball paradigms under two thermal conditions, normothermic time control and heat stress, on different days. For the heat stress trial, these paradigms were performed at preheat stress (i.e., normothermic) baseline, when esophageal temperature had increased by ~0.8°C, when esophageal temperature had increased by ~2.0°C, and during cooling following the heat stress. The reaction time and ERPs were recorded in each session. For the time control trial, subjects performed the auditory oddball paradigms at approximately the same time interval as they did in the heat stress trial. The peak latency and amplitude of an indicator of auditory processing (N100) were not altered regardless of thermal conditions. An indicator of stimulus classification/evaluation time (latency of P300) and the reaction time were shortened during heat stress; moreover an indicator of cognitive processing (the amplitude of P300) was significantly reduced during severe heat stress (8.3 ± 1.3 μV) relative to the baseline (12.2 ± 1.0 μV, P < 0.01). No changes in these indexes occurred during the time control trial. During subsequent whole body cooling, the amplitude of P300 remained reduced, and the reaction time and latency of P300 remained shortened. These results suggest that excessive elevations in internal temperature reduce cognitive processing but promote classification time.
AB - The effect of hyperthermia on cognitive function remains equivocal, perhaps because of methodological discrepancy. Using electroencephalographic eventrelated potentials (ERPs), we tested the hypothesis that a passive heat stress impairs cognitive processing. Thirteen volunteers performed repeated auditory oddball paradigms under two thermal conditions, normothermic time control and heat stress, on different days. For the heat stress trial, these paradigms were performed at preheat stress (i.e., normothermic) baseline, when esophageal temperature had increased by ~0.8°C, when esophageal temperature had increased by ~2.0°C, and during cooling following the heat stress. The reaction time and ERPs were recorded in each session. For the time control trial, subjects performed the auditory oddball paradigms at approximately the same time interval as they did in the heat stress trial. The peak latency and amplitude of an indicator of auditory processing (N100) were not altered regardless of thermal conditions. An indicator of stimulus classification/evaluation time (latency of P300) and the reaction time were shortened during heat stress; moreover an indicator of cognitive processing (the amplitude of P300) was significantly reduced during severe heat stress (8.3 ± 1.3 μV) relative to the baseline (12.2 ± 1.0 μV, P < 0.01). No changes in these indexes occurred during the time control trial. During subsequent whole body cooling, the amplitude of P300 remained reduced, and the reaction time and latency of P300 remained shortened. These results suggest that excessive elevations in internal temperature reduce cognitive processing but promote classification time.
KW - Auditory oddball paradigm
KW - Cognitive function
KW - Hyperthermia
KW - Reaction time
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U2 - 10.1152/ajpregu.00086.2016
DO - 10.1152/ajpregu.00086.2016
M3 - Article
C2 - 27101295
AN - SCOPUS:84984633105
SN - 0363-6119
VL - 311
SP - R33-R38
JO - American Journal of Physiology - Regulatory Integrative and Comparative Physiology
JF - American Journal of Physiology - Regulatory Integrative and Comparative Physiology
IS - 1
ER -