The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2

Medicine & Life Sciences

• palmitoyl-protein thioesterase 100%
• Substrate Specificity 62%
• Palmitoyl Coenzyme A 10%
• Fatty Acids 8%
• Ceroid lipofuscinosis, neuronal 1, infantile 5%
• Neuronal Ceroid-Lipofuscinoses 4%
• Lipids 4%
• Palmitates 4%
• Hydrolases 3%
• Proteins 3%
• Intellectual Disability 3%
• Transgenic Mice 2%
• Head 2%
• Aptitude 2%
• Neurons 2%
• Mutation 1%

Chemical Compounds

• Crystal Structure 27%
• Protein 23%
• Palmitoyl-CoA 9%
• Fatty Acid 5%
• Thioester 3%
• Disorder 2%
• Mutation 2%
• Amorphous Material 2%
• Length 1%