The Columnar Epithelial Cell of the Small Intestine: Digestion and Transport

Jerry D. Gardner, Michael S. Brown, Leonard Laster

Research output: Contribution to journalReview articlepeer-review


Cellular Digestion Carbohydrates In the western diet, carbohydrates are ingested almost entirely in the form of starch and the disaccharides, sucrose and lactose; free glucose accounts for less than 3 per cent of ingested carbohydrate.204 Pancreatic amylase initially attacks α-1,4 glycosidic bonds in the interior of starch molecules, producing oligosaccharides, which it hydrolyzes slowly to maltose and maltotriose.205 The α-1,6 branch points are not attacked, and “limit dextrins” of various sizes, containing glucose molecules surrounding α-1,6 branch points, remain. Pancreatic amylase is found not only in the intestinal lumen but also adsorbed to the lining epithelium,206,207 and under some conditions.

Original languageEnglish (US)
Pages (from-to)1317-1324
Number of pages8
JournalNew England Journal of Medicine
Issue number24
StatePublished - Dec 10 1970
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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